scholarly journals Targeted metabolomics of nonhuman primate serum after exposure to ionizing radiation: potential tools for high-throughput biodosimetry

RSC Advances ◽  
2016 ◽  
Vol 6 (56) ◽  
pp. 51192-51202 ◽  
Author(s):  
Evan L. Pannkuk ◽  
Evagelia C. Laiakis ◽  
Simon Authier ◽  
Karen Wong ◽  
Albert J. Fornace
Keyword(s):  
Ionizing Radiation ◽  
Health Effects ◽  
High Throughput ◽  
Nonhuman Primate ◽  
Absorbed Dose ◽  
Targeted Metabolomics ◽  
Potential Health ◽  
Nuclear Event

There is a need for research to rapidly determine an individual's absorbed dose and its potential health effects after a potential radiological or nuclear event that could expose large portions of a population to ionizing radiation (IR).

Radiation Biomarkers : Applications in Triage Management of Radiation Victims

2017 ◽  
Vol 2 (3) ◽  
pp. 270
Author(s):  
Saurabh Mishra ◽  
Raj Kumar
Keyword(s):  
Ionizing Radiation ◽  
Absorbed Dose ◽  
Physiological Status ◽  
Scenario Development ◽  
Potential Health ◽  
Biological Responses ◽  
Gene And Protein Expression ◽  
Genetic Perturbations ◽  
Biologic Response ◽  
Radiation Induced

Human exposure to ionizing radiation disrupts normal metabolic processes in cells and organs by inducing complex biological responses that interfere with gene and protein expression. Conventional dosimetry, monitoring of prodromal symptoms and peripheral lymphocyte counts are of limited value as organ- and tissue-specific biomarkers for personnel exposed to radiation, particularly, weeks or months after exposure. Analysis of metabolites generated in known stress-responsive pathways by molecular profiling helps to predict the physiological status of an individual in response to environmental or genetic perturbations. There is a need for research to rapidly determine an individual’s absorbed dose and its potential health effects after a potential radiological or nuclear event that could expose large portions of a population to ionizing radiation. Studies on biomarker identification after radiation exposure could contribute in biodosimetry, identifying individual dose absorbed, as well as biologic response, and administering immediate and proper medical care. In the recent scenario development of biomarker is major thrust area. In the present review paper articles related to gene biomarker, protein biomarker and metabolic biomarker are reviewed in order to sketch an overview on the recent advances related to developing an biomarker to assess the radiation induced toxicity.

Effect of ionizing radiation on the kinetics of hydrogenation on the Ni-MgO mixed catalyst

1982 ◽  
Vol 47 (7) ◽  
pp. 1780-1786 ◽  
Author(s):  
Rostislav Kudláček ◽  
Jan Lokoč
Keyword(s):  
Experimental Data ◽  
Activation Energy ◽  
Liquid Phase ◽  
Ionizing Radiation ◽  
Oxide Catalyst ◽  
Absorbed Dose ◽  
Hydrogenation Rate ◽  
Solution Composition ◽  
Mixed Catalyst ◽  
Kinetics Of

The effect of gamma pre-irradiation of the mixed nickel-magnesium oxide catalyst on the kinetics of hydrogenation of maleic acid in the liquid phase has been studied. The changes of the hydrogenation rate are compared with the changes of the adsorbed amount of the acid and with the changes of the solution composition, activation energy, and absorbed dose of the ionizing radiation. From this comparison and from the interpretation of the experimental data it can be deduced that two types of centers can be distinguished on the surface of the catalyst under study, namely the sorption centres for the acid and hydrogen and the reaction centres.

Accumulation and potential health effects of organohalogenated compounds in the arctic fox (Vulpes lagopus)—a review

2015 ◽  
Vol 502 ◽  
pp. 510-516 ◽  
Author(s):  
Kathrine Eggers Pedersen ◽  
Bjarne Styrishave ◽  
Christian Sonne ◽  
Rune Dietz ◽  
Bjørn Munro Jenssen
Keyword(s):  
Health Effects ◽  
The Arctic ◽  
Arctic Fox ◽  
Vulpes Lagopus ◽  
Potential Health

scholarly journals Review of the potential health effects of light and environmental exposures in underground workplaces

2019 ◽  
Vol 84 ◽  
pp. 201-209 ◽  
Author(s):  
Ei Ei Khaing Nang ◽  
Gulifeiya Abuduxike ◽  
Pawel Posadzki ◽  
Ushashree Divakar ◽  
Nanthini Visvalingam ◽  
...  
Keyword(s):  
Health Effects ◽  
Environmental Exposures ◽  
Potential Health
Sign in / Sign up

Export Citation Format

Share Document