Ionic liquid prolongs DNA translocation through graphene nanopores

RSC Advances ◽  
2016 ◽  
Vol 6 (51) ◽  
pp. 46019-46029 ◽  
Author(s):  
Mandar Kulkarni ◽  
Arnab Mukherjee
Keyword(s):  
Ionic Liquid ◽  
Dna Translocation ◽  
Translocation Speed ◽  
Graphene Nanopore

Ionic liquid molecules interact strongly with DNA and effectively reduce its translocation speed via graphene nanopore.

Molecular Insights into Geometric and Electrophoretic Effects on DNA Translocation Speed Through Graphene Nanoslit Sensor

2021 ◽  
Author(s):  
Changxiong Huang ◽  
Xiaohong Zhu ◽  
Zhen Li ◽  
Xinyao Ma ◽  
Na Li ◽  
...  
Keyword(s):  
Dna Translocation ◽  
Translocation Speed

scholarly journals Osmotically Driven and Detected DNA Translocations

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Angus McMullen ◽  
George Araujo ◽  
Michele Winter ◽  
Derek Stein
Keyword(s):  
Solid State ◽  
Salinity Gradient ◽  
Ionic Current ◽  
Dna Translocation ◽  
Dna Molecule ◽  
Salinity Gradients ◽  
Current Change ◽  
Theoretical Analyses ◽  
Translocation Speed

Abstract A salinity gradient propels a DNA molecule through a solid-state nanopore and generates an ionic current whose change allows for the detection of the translocation. Measurements and theoretical analyses reveal the role of diffusio-osmosis in driving these phenomena: After accounting for known salinity-dependent electrode effects, the measured current change caused by the presence of a DNA molecule inside the nanopore and the DNA translocation speed through it both increase with the magnitude of the applied salinity gradients. The effects are consistent with the theory of diffuisio-osmosis and strong enough to enable DNA translocations to overcome an applied retarding potential of tens of millivolts. This work illustrates how salinity gradients can be used to power and operate a nanopore sensor.

Theoretical studies on the dynamics of DNA fragment translocation through multilayer graphene nanopores

RSC Advances ◽  
2014 ◽  
Vol 4 (92) ◽  
pp. 50494-50502 ◽  
Author(s):  
Lijun Liang ◽  
Zhisen Zhang ◽  
Jiawei Shen ◽  
Kong Zhe ◽  
Qi Wang ◽  
...  
Keyword(s):  
Multilayer Graphene ◽  
Theoretical Studies ◽  
Dna Translocation ◽  
Dna Fragment ◽  
Graphene Nanopore

DNA translocation through multilayer graphene nanopore with a change of current.

Molecular Dynamics Study of DNA Translocation Through Graphene Nanopores With Controllable Speed

2015 ◽  
Author(s):  
Kun Li ◽  
Wei Si ◽  
Jingjie Sha ◽  
Yunfei Chen
Keyword(s):  
Molecular Dynamics ◽  
Ionic Current ◽  
Ionic Currents ◽  
Dna Bases ◽  
Dna Translocation ◽  
Dna Molecule ◽  
Long Time ◽  
Pulling Force ◽  
Current Blockage ◽  
Translocation Speed

All-atom steered molecular dynamics (SMD) simulations provide the means to study the single-stranded DNA (ssDNA) translocation through graphene nanopores at a controllable speed. The ssDNA is pulled by an elastic force similar to the manipulation by an AFM tip. At the same time, an electric field is applied across the reservoir along the direction of the pulling force, in order to hold the ssDNA strand taut and drive the ions in the solutions through the nanopore. By monitoring and analyzing the average ionic current blockage of poly(dA)10, poly(dC)10, poly(dG)10 and poly(dT)10, it is found that one can indeed discriminate the different DNA bases from each other by holding each nucleotide in the pore for sufficiently long time. It is obtained the average blocked ionic currents can be listed, in a increasing order, as IG<IA<IT, which is almost in agreement with the order of sizes of the four nucleotides (VG>VA>VT>VC), apart from C. The results indicate that physical occupancy of the nucleotide plays the major role in affecting average blocked ionic current when the DNA translocation speed is effectively slowed down. This work provides a clue for the further investigation to realize the discrimination of the four nucleotides by the method of actively controlling DNA molecule translocation speed through the nanopores.

scholarly journals The impact of the number of layers of a graphene nanopore on DNA translocation

Soft Matter ◽  
2013 ◽  
Vol 9 (3) ◽  
pp. 960-966 ◽  
Author(s):  
Wenping Lv ◽  
Maodu Chen ◽  
Ren'an Wu
Keyword(s):  
Dna Translocation ◽  
Number Of Layers ◽  
The Impact ◽  
Graphene Nanopore

scholarly journals Slowing Down DNA Translocation Speed thorough a Nanopore by a Nanofibre Meshed Layer

2018 ◽  
Vol 114 (3) ◽  
pp. 180a
Author(s):  
Daming Zhou ◽  
Yue Zhao ◽  
Enling Tian ◽  
Deqiang Wang
Keyword(s):  
Dna Translocation ◽  
Slowing Down ◽  
Translocation Speed

Soft ionic liquid based resistive memory characteristics in a two terminal discrete polydimethylsiloxane cylindrical microchannel

2020 ◽  
Vol 8 (38) ◽  
pp. 13368-13374
Author(s):  
Muhammad Umair Khan ◽  
Gul Hassan ◽  
Jinho Bae
Keyword(s):  
Ionic Liquid ◽  
Acrylic Acid ◽  
Sodium Hydroxide ◽  
Sodium Salt ◽  
Resistive Memory ◽  
Cylindrical Microchannel ◽  
Memory Characteristics ◽  
Poly Acrylic Acid

This paper proposes a novel soft ionic liquid (IL) electrically functional device that displays resistive memory characteristics using poly(acrylic acid) partial sodium salt (PAA-Na+:H2O) solution gel and sodium hydroxide (NaOH) in a thin polydimethylsiloxane (PDMS) cylindrical microchannel.

Sign in / Sign up

Export Citation Format

Share Document