A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C–O and C–N bond formation approach

RSC Advances ◽  
2016 ◽  
Vol 6 (46) ◽  
pp. 39563-39567 ◽  
Author(s):  
Pengfeng Guo ◽  
Changcheng Wang ◽  
Ya Chen ◽  
Caijun Ou ◽  
Hangqi Jiang ◽  
...  
Keyword(s):  
Aromatic Amine ◽  
Bond Formation ◽  
Domino Reaction ◽  
Aliphatic Acid ◽  
One Pot ◽  
Furan Derivatives ◽  
Dicarbonyl Compounds ◽  
Metal Free

A novel one pot, metal-free, three-component domino reaction for the formation of furan derivatives has been developed from 3-phenylpropiolaldehyde, 1,3-dicarbonyl compounds and aromatic amine or aliphatic acid.

One-pot synthesis of α,β-epoxy ketones through domino reaction between alkenes and aldehydes catalyzed by proline based chiral organocatalysts

2017 ◽  
Vol 15 (12) ◽  
pp. 2551-2561 ◽  
Author(s):  
Veeramanoharan Ashokkumar ◽  
Ayyanar Siva
Keyword(s):  
Good Yield ◽  
Bond Formation ◽  
Direct Access ◽  
Domino Reaction ◽  
One Pot ◽  
New Approach ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Epoxy Ketones

A proline based metal free organocatalysts developed by new approach for the synthesis of epoxide derivatives through domino reaction. This domino reaction allows the direct access to epoxide from various alkene and aldehyde through C–H functionalization and C–C/C–O bond formation. The catalytic efficiencies of organocatalysts were also determined by domino reaction with very good yield (up to 95 %) and ee's (up to 99 %).

Transition-Metal-Free Catalysis for the Reductive ­Functionalization of CO2 with Amines

Synlett ◽  
2018 ◽  
Vol 29 (05) ◽  
pp. 548-555 ◽  
Author(s):  
Liang-Nian He ◽  
Xiao-Fang Liu ◽  
Xiao-Ya Li ◽  
Chang Qiao
Keyword(s):  
Transition Metal ◽  
Energy Content ◽  
Bond Formation ◽  
Energy Storage Materials ◽  
One Pot ◽  
Metal Free ◽  
Recent Developments ◽  
Electron Reduction ◽  
Reduction Of Co2 ◽  
Hierarchical Reduction

Reductive functionalization of CO2 with amines and a reductant, which combines both reduction of CO2 and C–N bond formation in one pot to produce versatile chemicals and energy-storage materials such as formamides, aminals, and methylamines that are usually derived from petroleum feedstock, would be appealing and promising. Herein, we give a brief review on recent developments in the titled CO2 chemistry by employing transition-metal-free catalysis, which can be catalogued as below according to the diversified energy content of the products, that is formamides, aminals, and methylamines being consistent with 2-, 4-, and 6-electron reduction of CO2, respectively. Notably, hierarchical reduction of CO2 with amines to afford at least two products, for example, formamides and methylamines, could be realized with the same catalyst through tuning the hydrosilane type, reaction temperature, or CO2 pressure. Finally, the opportunities and challenges of the reductive functionalization of CO2 with amines are also highlighted.1 Introduction2 2-Electron Reduction of CO2 to Formamide3 6-Electron Reduction of CO2 to Methylamine4 4-Electron Reduction of CO2 to Aminal5 Hierarchical Reduction of CO2 with Amines6 Conclusion

A facile and highly convergent approach to thiazolo[3,2-a]pyridines via one-pot multicomponent domino reaction under metal-free and solvent-free conditions

Tetrahedron ◽  
2015 ◽  
Vol 71 (21) ◽  
pp. 3422-3427 ◽  
Author(s):  
Anugula Nagaraju ◽  
B. Janaki Ramulu ◽  
Gaurav Shukla ◽  
Abhijeet Srivastava ◽  
Girijesh Kumar Verma ◽  
...  
Keyword(s):  
Solvent Free ◽  
Domino Reaction ◽  
One Pot ◽  
Metal Free ◽  
Solvent Free Conditions ◽  
Convergent Approach

B2(OH)4-mediated one-pot synthesis of tetrahydroquinoxalines from 2-amino(nitro)anilines and 1,2-dicarbonyl compounds in water

2017 ◽  
Vol 4 (11) ◽  
pp. 2175-2178 ◽  
Author(s):  
Sensheng Liu ◽  
Yanmei Zhou ◽  
Yuebo Sui ◽  
Huan Liu ◽  
Haifeng Zhou
Keyword(s):  
Hydrogen Donor ◽  
One Pot ◽  
Dicarbonyl Compounds ◽  
Metal Free ◽  
One Pot Synthesis

A practical one-pot synthesis of tetrahydroquinoxalines from readily available 2-amino(nitro)anilines and 1,2-dicarbonyl compounds mediated by diboronic acid with water as both a solvent and a hydrogen donor under metal-free conditions has been discovered.

A New Multicomponent Domino Reaction of 1,3-Dicarbonyl Compounds:  One-Pot Access to PolycyclicN/O-,N/S-, andN/N-Aminals

2001 ◽  
Vol 3 (14) ◽  
pp. 2145-2148 ◽  
Author(s):  
Céline Simon ◽  
Jean-François Peyronel ◽  
Jean Rodriguez
Keyword(s):  
Domino Reaction ◽  
One Pot ◽  
Dicarbonyl Compounds

Metal-Free CN- and NN-Bond Formation: Synthesis of 1,2,3-Triazoles from Ketones,N-Tosylhydrazines, and Amines in One Pot

2014 ◽  
Vol 20 (52) ◽  
pp. 17635-17639 ◽  
Author(s):  
Zhengkai Chen ◽  
Qiangqiang Yan ◽  
Zhanxiang Liu ◽  
Yuhong Zhang
Keyword(s):  
Bond Formation ◽  
One Pot ◽  
Metal Free

ChemInform Abstract: Metal-Free One-Pot Domino Reaction: Chemoselective Synthesis of Polyarylated Oxazoles.

ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Hua Meng ◽  
You Zi ◽  
Xiao-Ping Xu ◽  
Shun-Jun Ji
Keyword(s):  
Domino Reaction ◽  
One Pot ◽  
Metal Free ◽  
Chemoselective Synthesis

ChemInform Abstract: Metal-Free One-Pot Synthesis of 1,3-Diazaheterocyclic Compounds via I2-Mediated Oxidative C-N Bond Formation.

ChemInform ◽  
2015 ◽  
Vol 46 (48) ◽  
pp. no-no
Author(s):  
Xianhai Tian ◽  
Lina Song ◽  
Ertong Li ◽  
Qiang Wang ◽  
Wenquan Yu ◽  
...  
Keyword(s):  
Bond Formation ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis

ChemInform Abstract: Metal-Free C-N- and N-N-Bond Formation: Synthesis of 1,2,3-Triazoles from Ketones, N-Tosylhydrazines, and Amines in One Pot.

ChemInform ◽  
2015 ◽  
Vol 46 (21) ◽  
pp. no-no
Author(s):  
Zhengkai Chen ◽  
Qiangqiang Yan ◽  
Zhanxiang Liu ◽  
Yuhong Zhang
Keyword(s):  
Bond Formation ◽  
One Pot ◽  
Metal Free
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