Synthesis and characterization of an enzyme-degradable zwitterionic dextran hydrogel

RSC Advances ◽  
2016 ◽  
Vol 6 (37) ◽  
pp. 30862-30866 ◽  
Author(s):  
Haiyan Wu ◽  
Huifeng Wang ◽  
Fang Cheng ◽  
Fujian Xu ◽  
Gang Cheng
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Matrix Metalloproteinase ◽  
Protein Adsorption ◽  
Cell Attachment ◽  
Synthesis And Characterization ◽  
Engineering Applications ◽  
Soft Tissue Engineering ◽  
Nonspecific Protein Adsorption

A matrix metalloproteinase peptide cross-linked dextran hydrogel was synthesized. Dextran was modified with carboxybetaine to resist nonspecific protein adsorption and cell attachment. The degradable hydrogel is a good candidate for soft tissue engineering applications.

Synthesis and characterization of biodegradable lysine-based waterborne polyurethane for soft tissue engineering applications

2016 ◽  
Vol 4 (11) ◽  
pp. 1682-1690 ◽  
Author(s):  
Hongye Hao ◽  
Jingyu Shao ◽  
Ya Deng ◽  
Shan He ◽  
Feng Luo ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Soft Tissue ◽  
Tissue Repair ◽  
Waterborne Polyurethane ◽  
Synthesis And Characterization ◽  
Soft Tissue Repair ◽  
Waterborne Polyurethanes ◽  
Soft Tissue Engineering

Light-crosslinking waterborne polyurethanes (LWPUs) based on lysine possess appropriate elasticity for soft tissue repair, and can induce macrophages into a wound healing phenotype.

Synthesis and characterization of poly(glycerol sebacate)-based elastomeric copolyesters for tissue engineering applications

2016 ◽  
Vol 7 (14) ◽  
pp. 2553-2564 ◽  
Author(s):  
Yating Jia ◽  
Weizhong Wang ◽  
Xiaojun Zhou ◽  
Wei Nie ◽  
Liang Chen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Water Uptake ◽  
Synthesis And Characterization ◽  
Uptake Capacity ◽  
Engineering Applications ◽  
Water Uptake Capacity

A poly(glycerol sebacate)-based elastomeric copolyesters with improved mechanical properties and higher water uptake capacity.

scholarly journals Development of Photocrosslinkable Urethane-Doped Polyester Elastomers for Soft Tissue Engineering

2011 ◽  
Vol 1 (1) ◽  
pp. 18-31 ◽  
Author(s):  
Yi Zhang ◽  
Richard T. Tran ◽  
Dipendra Gyawali ◽  
Jian Yang
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Soft Tissue ◽  
Hexamethylene Diisocyanate ◽  
Elongation At Break ◽  
Thermally Induced ◽  
Molar Ratios ◽  
3D Network ◽  
Soft Tissue Engineering

Finding an ideal biomaterial with the proper mechanical properties and biocompatibility has been of intense focus in the field of soft tissue engineering. This paper reports on the synthesis and characterization of a novel crosslinked urethane-doped polyester elastomer (CUPOMC), which was synthesized by reacting a previously developed photocrosslinkable poly (octamethylene maleate citrate) (POMC) prepolymers (pre-POMC) with 1,6-hexamethylene diisocyanate (HDI) followed by thermo- or photo-crosslinking polymerization. The mechanical properties of the CUPOMCs can be tuned by controlling the molar ratios of pre-POMC monomers, and the ratio between the prepolymer and HDI. CUPOMCs can be crosslinked into a 3D network through polycondensation or free radical polymerization reactions. The tensile strength and elongation at break of CUPOMC synthesized under the known conditions range from 0.73±0.12MPa to 10.91±0.64MPa and from 72.91±9.09% to 300.41±21.99% respectively. Preliminary biocompatibility tests demonstrated that CUPOMCs support cell adhesion and proliferation. Unlike the pre-polymers of other crosslinked elastomers, CUPOMC pre-polymers possess great processability demonstrated by scaffold fabrication via a thermally induced phase separation method. The dual crosslinking methods for CUPOMC pre-polymers should enhance the versatile processability of the CUPOMC used in various conditions. Development of CUPOMC should expand the choices of available biodegradable elastomers for various biomedical applications such as soft tissue engineering.

Synthesis and characterization of novel mesoporous strontium-modified bioactive glass nanospheres for bone tissue engineering applications

2020 ◽  
Vol 294 ◽  
pp. 109889 ◽  
Author(s):  
Amir Hossein Taghvaei ◽  
Forough Danaeifar ◽  
Christoph Gammer ◽  
Jürgen Eckert ◽  
Sadjad Khosravimelal ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Synthesis And Characterization ◽  
Engineering Applications

Synthesis and Characterization of Electroactive Gellan Gum Spongy-Like Hydrogels for Skeletal Muscle Tissue Engineering Applications

2017 ◽  
Vol 23 (17-18) ◽  
pp. 968-979 ◽  
Author(s):  
Fernanda V. Berti ◽  
Pathomthat Srisuk ◽  
Lucília P. da Silva ◽  
Alexandra P. Marques ◽  
Rui L. Reis ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Tissue Engineering ◽  
Muscle Tissue ◽  
Gellan Gum ◽  
Skeletal Muscle Tissue ◽  
Synthesis And Characterization ◽  
Engineering Applications

Synthesis and characterization of a photocrosslinkable chitosan–gelatin hydrogel aimed for tissue regeneration

RSC Advances ◽  
2015 ◽  
Vol 5 (78) ◽  
pp. 63478-63488 ◽  
Author(s):  
Sofia M. Saraiva ◽  
Sónia P. Miguel ◽  
Maximiano P. Ribeiro ◽  
Paula Coutinho ◽  
Ilídio J. Correia
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Tissue Regeneration ◽  
Synthesis And Characterization ◽  
Native Structure ◽  
Engineering Applications ◽  
Gelatin Hydrogel

In the area of regenerative medicine different approaches have been studied to restore the native structure of damaged tissues. Herein, the suitability of a photocrosslinkable hydrogel for tissue engineering applications was studied.

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