Synthesis and biological properties of water-soluble polyphenylthiophene brushes with poly(ethylene glycol)/polyzwitterion side chains

2017 ◽  
Vol 8 (10) ◽  
pp. 1672-1679 ◽  
Author(s):  
Yajun Zhang ◽  
Zhengkui Zhang ◽  
Changren Liu ◽  
Weizhi Chen ◽  
Cheng Li ◽  
...  

Two types of water-soluble polyphenylthiophene brushes with poly(ethylene glycol) and polyzwitterion side chains were synthesized and studied as bioprobes.

2007 ◽  
Vol 43 (4) ◽  
pp. 1288-1301 ◽  
Author(s):  
Fabienne Barroso-Bujans ◽  
Ricardo Martínez ◽  
Mehrdad Yazdani-Pedram ◽  
Pedro Ortiz ◽  
Holger Frey

2007 ◽  
Vol 342-343 ◽  
pp. 425-428 ◽  
Author(s):  
Dhananjay Jere ◽  
Tae Hee Kim ◽  
Rohidas B. Arote ◽  
Hu Lin Jiang ◽  
Myung Haing Cho ◽  
...  

Vectors are vital aspect of gene delivery system which decides the success of gene therapy. Efficient transfection with minimum or no toxicity, are two principal aims of any gene delivery system. In this our study, we rationally developed biodegradable water soluble poly(ßamino ester) (PAE) based on spermine (SPR) and poly (ethylene glycol) (PEG), by Michael-type addition reaction and further studied for its potential as a gene carrier. Confirmation of synthesized PAE was done by proton NMR spectroscopy. In gel retardation assay, the PAEs have shown good DNA binding ability over wide range of polyplexes. The addition of PEG over SPR resulted in a novel PAE with higher degree of safety and transfection efficiency as compared with polyethylenimine 25K (PEI) when studied in 293T human kidney carcinoma cells.


1999 ◽  
Vol 61 (3) ◽  
pp. 281-294 ◽  
Author(s):  
Richard B Greenwald ◽  
Charles D Conover ◽  
Annapurna Pendri ◽  
Yun H Choe ◽  
Anthony Martinez ◽  
...  

2012 ◽  
Vol 126 (4) ◽  
pp. 1359-1368 ◽  
Author(s):  
Placido Mineo ◽  
Rossana Alicata ◽  
Norberto Micali ◽  
Valentina Villari ◽  
Emilio Scamporrino

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