Oxidative decarbonylative coupling of aliphatic aldehydes with methacryloyl benzamides to generate isoquinoline-1,3(2H,4H)-diones

2017 ◽  
Vol 15 (5) ◽  
pp. 1096-1099 ◽  
Author(s):  
Changduo Pan ◽  
Chaoyue Chen ◽  
Jin-Tao Yu
Keyword(s):  
Radical Addition ◽  
Aliphatic Aldehydes

Alkyl-substituted isoquinoline-1,3(2H,4H)-diones were prepared by coupling of N-alkyl-N-methacryloylbenzamides and aliphatic aldehydes through subsequent decarbonylation, radical addition and cyclization processes.

Co-Catalyzed decarbonylative alkylative esterification of styrenes with aliphatic aldehydes and hypervalent iodine(iii) reagents

2019 ◽  
Vol 6 (17) ◽  
pp. 3065-3070 ◽  
Author(s):  
Yong Peng ◽  
Yuan-Yuan Jiang ◽  
Xue-Jiao Du ◽  
Da-You Ma ◽  
Luo Yang
Keyword(s):  
Radical Addition ◽  
Hypervalent Iodine ◽  
Aliphatic Aldehydes ◽  
Alkyl Radicals

Decarbonylation of aliphatic aldehydes into 1°, 2° and 3° alkyl radicals to construct C(sp3)–C(sp3) bond via radical addition and C(sp3)–O bond via the interconversion of CoII–CoIII–CoI.

A new chemical modification of liquid polybutadienes: Radical addition of aliphatic aldehydes onto pending vinyl groups

2008 ◽  
Vol 46 (12) ◽  
pp. 3919-3925 ◽  
Author(s):  
Jiří Podešva ◽  
Martin Hrubý ◽  
Jiří Spěváček ◽  
Miluše Hrdličková ◽  
Miloš Netopilík
Keyword(s):  
Chemical Modification ◽  
Radical Addition ◽  
Aliphatic Aldehydes

scholarly journals Fe-catalyzed Decarbonylative Alkylative Spirocyclization of N-Arylcinnamamides: Access to Alkylated 1-Azaspirocyclohexadienones

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 432
Author(s):  
Xiang Peng ◽  
Ren-Xiang Liu ◽  
Xiang-Yan Xiao ◽  
Luo Yang
Keyword(s):  
Radical Addition ◽  
Aliphatic Aldehydes ◽  
Alkyl Radicals ◽  
Alkyl Groups ◽  
Tertiary Alkyl

For the convenient introduction of simple linear/branched alkyl groups into biologically important azaspirocyclohexadienones, a practical Fe-catalyzed decarbonylative cascade spiro-cyclization of N-aryl cinnamamides with aliphatic aldehydes to provide alkylated 1-azaspiro-cyclohexadienones was developed. Aliphatic aldehydes were oxidative decarbonylated into primary, secondary and tertiary alkyl radicals conveniently and allows for the subsequent cascade construction of dual C(sp3)-C(sp3) and C=O bonds via radical addition, spirocyclization and oxidation sequence.

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