Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry

2016 ◽  
Vol 14 (32) ◽  
pp. 7777-7791 ◽  
Author(s):  
Antoine Lizzul-Jurse ◽  
Laetitia Bailly ◽  
Marie Hubert-Roux ◽  
Carlos Afonso ◽  
Pierre-Yves Renard ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Ionization Efficiency

A family of readily functionalizable phosphonium-tagged fluorescent coumarins is reported. Their utility was illustrated through the preparation of a FRET-based protease-sensitive probe which exhibited increased electrospray ionization efficiency.

Ultra-Low Flow Electrospray Ionization-Mass Spectrometry for Improved Ionization Efficiency in Phosphoproteomics

2012 ◽  
Vol 84 (10) ◽  
pp. 4552-4559 ◽  
Author(s):  
Anthonius A. M. Heemskerk ◽  
Jean-Marc Busnel ◽  
Bart Schoenmaker ◽  
Rico J. E. Derks ◽  
Oleg Klychnikov ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Ionization Efficiency ◽  
Ionization Mass Spectrometry ◽  
Low Flow ◽  
Ionization Mass
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