Design and synthesis of a novel fluorescent benzo[g]imidazo[4,5-c]quinoline nucleoside for monitoring base-pair-induced protonation with cytosine: distinguishing cytosine via changes in the intensity and wavelength of fluorescence

2016 ◽  
Vol 14 (16) ◽  
pp. 3934-3942 ◽  
Author(s):  
Shogo Siraiwa ◽  
Azusa Suzuki ◽  
Ryuzi Katoh ◽  
Yoshio Saito

A novel fluorescent benzo[g]imidazo[4,5-c]quinoline nucleoside BIQA was developed and used to monitor BIQA–C base-pair formation in ODN duplexes.

2007 ◽  
Vol 36 (3) ◽  
pp. 839-848 ◽  
Author(s):  
Aya Kitamura ◽  
Paul J. Jardine ◽  
Dwight L. Anderson ◽  
Shelley Grimes ◽  
Hiroshi Matsuo

2011 ◽  
Vol 133 (19) ◽  
pp. 7272-7275 ◽  
Author(s):  
Yosuke Taniguchi ◽  
Ryota Kawaguchi ◽  
Shigeki Sasaki
Keyword(s):  

Science ◽  
2014 ◽  
Vol 344 (6179) ◽  
pp. 55-58 ◽  
Author(s):  
Narayana Annaluru ◽  
Héloïse Muller ◽  
Leslie A. Mitchell ◽  
Sivaprakash Ramalingam ◽  
Giovanni Stracquadanio ◽  
...  

Rapid advances in DNA synthesis techniques have made it possible to engineer viruses, biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a functional 272,871–base pair designer eukaryotic chromosome, synIII, which is based on the 316,617–base pair native Saccharomyces cerevisiae chromosome III. Changes to synIII include TAG/TAA stop-codon replacements, deletion of subtelomeric regions, introns, transfer RNAs, transposons, and silent mating loci as well as insertion of loxPsym sites to enable genome scrambling. SynIII is functional in S. cerevisiae. Scrambling of the chromosome in a heterozygous diploid reveals a large increase in a-mater derivatives resulting from loss of the MATα allele on synIII. The complete design and synthesis of synIII establishes S. cerevisiae as the basis for designer eukaryotic genome biology.


ChemInform ◽  
2014 ◽  
Vol 45 (29) ◽  
pp. no-no
Author(s):  
Yun Chai ◽  
Ananya Paul ◽  
Michael Rettig ◽  
W. David Wilson ◽  
David W. Boykin

2018 ◽  
Vol 114 (3) ◽  
pp. 597a-598a
Author(s):  
Marisa Mitchell ◽  
Carolina Dunbar ◽  
Thao Tran ◽  
Brian Cannon

CrystEngComm ◽  
2012 ◽  
Vol 14 (11) ◽  
pp. 3851 ◽  
Author(s):  
Sathyanarayana Reddy Perumalla ◽  
Changquan Calvin Sun

1995 ◽  
Vol 117 (23) ◽  
pp. 6287-6291 ◽  
Author(s):  
Changmoon Park ◽  
Judy L. Campbell ◽  
William A. Goddard

1968 ◽  
Vol 31 (1) ◽  
pp. 91-99 ◽  
Author(s):  
Jesse S. Binford ◽  
Dennis M. Holloway
Keyword(s):  

2012 ◽  
Vol 18 (24) ◽  
pp. 7434-7442 ◽  
Author(s):  
Charlotte S. Madsen ◽  
Sarah Witzke ◽  
Pawan Kumar ◽  
Kushuma Negi ◽  
Pawan K. Sharma ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document