scholarly journals Delivering aminopyridine ligands into cancer cells through conjugation to the cell-penetrating peptide BP16

2016 ◽  
Vol 14 (17) ◽  
pp. 4061-4070 ◽  
Author(s):  
M. Soler ◽  
M. González-Bártulos ◽  
E. Figueras ◽  
A. Massaguer ◽  
L. Feliu ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cell Penetrating Peptide ◽  
Peptide Conjugates ◽  
Cell Penetrating ◽  
High Cytotoxicity

Peptide conjugates incorporating a red-ox active aminopyridine ligand bound to the cell-penetrating peptide BP16 display high cytotoxicity.

18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells

2012 ◽  
Vol 39 (8) ◽  
pp. 1202-1212 ◽  
Author(s):  
Susan Richter ◽  
Vincent Bouvet ◽  
Melinda Wuest ◽  
Ralf Bergmann ◽  
Joerg Steinbach ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Cell Uptake ◽  
Cell Penetrating Peptide ◽  
Human Cancer Cells ◽  
Cell Penetrating

scholarly journals Evaluation of cell penetrating peptide coated Mn:ZnS nanoparticles for paclitaxel delivery to cancer cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
N. Sanoj Rejinold ◽  
Yunho Han ◽  
Jisang Yoo ◽  
Hae Yong Seok ◽  
Ji Ho Park ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating

Lipid–Cell-Penetrating-Peptide Conjugates as Effective Delivery Systems

Synlett ◽  
2017 ◽  
Vol 28 (15) ◽  
pp. 1897-1900
Author(s):  
Zi-Gang Li ◽  
Yan-Hong Jiang ◽  
Hui Zhao ◽  
Yuan Tian
Keyword(s):  
Cellular Uptake ◽  
Biological Research ◽  
Cell Penetrating Peptide ◽  
Peptide Conjugates ◽  
Cellular Toxicity ◽  
Wide Range ◽  
Cell Penetrating ◽  
Effective Delivery ◽  
Cellular Permeability ◽  
Small Molecule Therapeutics

A lipid–cell-penetrating-peptide (CPP) conjugate was designed to deliver cargoes with poor cellular permeability, including peptides or small-molecule therapeutics, into cells. The lipid–CPP conjugate facilitated the cellular uptake of cargoes noncovalently through an ATP-dependent micropinocytosis mechanism. This delivery system is simple, efficient, has minimal cellular toxicity, and might be useful in a wide range of biological research.

scholarly journals Novel cell-penetrating-amyloid peptide conjugates preferentially kill cancer cells

MedChemComm ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 121-130 ◽  
Author(s):  
John R. Veloria ◽  
Luxi Chen ◽  
Lin Li ◽  
Gail A. M. Breen ◽  
Jiyong Lee ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Diseases ◽  
Amyloid Peptide ◽  
Toxic Effects ◽  
Peptide Conjugates ◽  
Amyloid A ◽  
Cell Penetrating

The goal of this study was to develop a peptide which could use the toxic effects of amyloid, a substance which is the hallmark of over 25 known human diseases, to selectively kill cancer cells.

Design of Acid-Activated Cell Penetrating Peptide for Delivery of Active Molecules into Cancer Cells

2011 ◽  
Vol 22 (7) ◽  
pp. 1410-1415 ◽  
Author(s):  
Wei Zhang ◽  
Jingjing Song ◽  
Bangzhi Zhang ◽  
Liwei Liu ◽  
Kairong Wang ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating

scholarly journals Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer

Drug Delivery ◽  
2017 ◽  
Vol 24 (1) ◽  
pp. 752-764 ◽  
Author(s):  
Ziqing Duan ◽  
Cuitian Chen ◽  
Jing Qin ◽  
Qi Liu ◽  
Qi Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Antitumor Effect ◽  
Cell Penetrating Peptide ◽  
Drug Resistant ◽  
Peptide Conjugates ◽  
Cell Penetrating

Enzyme-triggered delivery of chlorambucil from conjugates based on the cell-penetrating peptide BP16

2015 ◽  
Vol 13 (5) ◽  
pp. 1470-1480 ◽  
Author(s):  
Marta Soler ◽  
Marta González-Bártulos ◽  
Eduard Figueras ◽  
Xavi Ribas ◽  
Miquel Costas ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Uptake And Release

The combination of the cell-penetrating peptide BP16 with the enzymatic cleavable sequence Gly-Phe-Leu-Gly constitutes a drug delivery system for the effective uptake and release of chlorambucil in cancer cells.

A Cell-Penetrating Peptide Targeting AAC-11 Specifically Induces Cancer Cells Death

2016 ◽  
Vol 76 (18) ◽  
pp. 5479-5490 ◽  
Author(s):  
Léonard Jagot-Lacoussiere ◽  
Ewa Kotula ◽  
Bruno O. Villoutreix ◽  
Heriberto Bruzzoni-Giovanelli ◽  
Jean-Luc Poyet
Keyword(s):  
Cancer Cells ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
A Cell ◽  
Peptide Targeting ◽  
Cells Death
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