scholarly journals High density 3D printed microfluidic valves, pumps, and multiplexers

Lab on a Chip ◽  
2016 ◽  
Vol 16 (13) ◽  
pp. 2450-2458 ◽  
Author(s):  
Hua Gong ◽  
Adam T. Woolley ◽  
Gregory P. Nordin
Keyword(s):  
Optical Properties ◽  
Microfluidic Devices ◽  
High Density ◽  
3D Printer ◽  
Active Elements ◽  
3D Printed ◽  
3D Layout ◽  
The Right ◽  
Microfluidic Valves

We demonstrate that a custom resin with the right optical properties enables a digital light processor stereolithographic (DLP-SLA) 3D printer to fabricate microfluidic devices with densely integrated active elements in a 3D layout.

scholarly journals Gold nanoparticles embedded in a polymer as a 3D-printable dichroic nanocomposite material

2019 ◽  
Vol 10 ◽  
pp. 442-447 ◽  
Author(s):  
Lars Kool ◽  
Anton Bunschoten ◽  
Aldrik H Velders ◽  
Vittorio Saggiomo
Keyword(s):  
Mechanical Properties ◽  
Gold Nanoparticles ◽  
Optical Properties ◽  
3D Printing ◽  
Optical Filters ◽  
Manufacturing Processes ◽  
3D Printer ◽  
Minute Amount ◽  
3D Objects ◽  
3D Printed

Background: Nanotechnology, even if unknowingly, has been used for millennia. The occurrence of shiny colors in pottery and glass made hundreds and thousand of years ago is due to the presence of nanoparticles in the fabrication of such ornaments. In the last decade, 3D printing has revolutionized fabrication and manufacturing processes, making it easier to produce, in a simple and fast way, 3D objects. Results: In this paper we show how to fabricate a 3D-printable nanocomposite composed of dichroic gold nanoparticles and a 3D-printable polymer. The minute amount of gold nanoparticles used for obtaining the dichroic effect does not influence the mechanical properties of the polymer nor its printability. Thus, the nanocomposite can be easily 3D-printed using a standard 3D printer and shows a purple color in transmission and a brownish color in reflection. Conclusion: This methodology can be used not only by artists, but also for studying the optical properties of nanoparticles or, for example, for the 3D fabrication of optical filters.

scholarly journals 3D-Printed Autonomous Capillaric Circuits†

2016 ◽  
Author(s):  
A. O. Olanrewaju ◽  
A. Robillard ◽  
M. Dagher ◽  
D. Juncker
Keyword(s):  
3D Printing ◽  
Circuit Design ◽  
Microfluidic Devices ◽  
Electrical Circuit ◽  
3D Printer ◽  
Design Rules ◽  
Micro Scale ◽  
Potential Applications ◽  
3D Printed ◽  
Research And Education

AbstractCapillaric circuits (CCs) are advanced capillary microfluidic devices that move liquids in complex pre-programmed sequences without external pumps and valves-relying instead on microfluidic control elements powered by capillary forces. CCs were thought to require high-precision micro-scale features manufactured by photolithography in a cleanroom, which is slow and expensive. Here we present rapidly and inexpensively 3D-printed autonomous CCs. Molds for CCs were fabricated with a benchtop 3D-printer, Poly(dimethylsiloxane) replicas were made, and fluidic functionality was verified with aqueous solutions. We established design rules for 3D-printed CCs by a combination of modelling and experimentation. The functionality and reliability of 3D-printed trigger valves-an essential fluidic element that stops one liquid until flow is triggered by a second liquid-was tested for different geometries and different solutions. Trigger valves with geometries up to 80-fold larger than cleanroom-fabricated ones were found to function reliably. We designed 3D-printed retention burst valves that encode sequential liquid drainage and delivery using capillary pressure differences encoded by varying valve height and width. Using an electrical circuit analogue of the CC, we established circuit design rules for ensuring strictly sequential liquid delivery. We realized a 3D-printed CC with reservoir volumes 60 times larger than cleanroom-fabricated circuits and autonomously delivered eight liquids in a pre-determined sequence in < 7 min, exceeding the number of sequentially-encoded, self-regulated fluidic delivery events apreviously reported. Taken together, our results demonstrate that 3D-printing enables rapid prototyping of reliable CCs with improved functionality and potential applications in diagnostics, research and education.

On the Application of Biomimicked Composites in 3D Printed Artifacts

2017 ◽  
Author(s):  
Seyed M. Allameh ◽  
Roger Miller
Keyword(s):  
3D Printing ◽  
Fracture Energy ◽  
3D Printer ◽  
Works Of Art ◽  
3D Printers ◽  
3D Printed ◽  
Series Of Experiments ◽  
Architectural Structures ◽  
Soft Polymer ◽  
The Right

Application of 3D printing to works of art is not new. However, with the advent of larger and more affordable 3D printers, it is possible to fabricate works of art including statues, sculptures, and architectural structures from biomimicked composites. Made of hard ceramic and soft polymer with or without reinforcement, these composites have shown to be much tougher than their monolithic counterparts. The use of biomimicking will increase the durability and strength of such artifacts. In this study, a newly developed architectural 3D printer is used to create works of art using concrete, with and without reinforcement fibers. The challenge that face creating tough artistic display structures include durability, hardness and resistance to impact. To determine the right combination of hard ceramic and soft polymer, a series of experiments were conducted. These included the fabrication of biomimicked composites with different materials and testing them for fracture energy as well as maximum strength. Earlier published works demonstrate the effect of various parameters such as type of ceramic layer, layering, fiber reinforcement type, fiber length, and fiber loading. In this paper, the effect of hard layer thickness and the type of polymer on the mechanical properties of the biomimicked composites was investigated. Preliminary results show the highest fracture energy for composites made with concrete bonding adhesive (CBA) and Quikrete™ concrete, with a spacing of 5mm. The application of 3D printing to the educational activities of a museum in Newport KY will be explained and its implication in relation with civic engagement activities of Northern Kentucky University will be elucidated.

scholarly journals Author Correction: Crystal structure and optical properties of a high-density InGaN nanoumbrella array as a white light source without phosphors

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Tetsuya Kouno ◽  
Masaru Sakai ◽  
Katsumi Kishino ◽  
Akihiko Kikuchi ◽  
Naoki Umehara ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Optical Properties ◽  
Light Source ◽  
White Light ◽  
High Density ◽  
White Light Source

A Correction to this paper has been published: https://doi.org/10.1038/s41427-021-00298-9

scholarly journals Design and characterization of 3D printed, neomycin-eluting poly-L-lactide mats for wound-healing applications

2021 ◽  
Vol 32 (4) ◽  
Author(s):  
Mahima Singh ◽  
Sriramakamal Jonnalagadda
Keyword(s):  
Release Kinetics ◽  
Biological Properties ◽  
In Vitro Dissolution ◽  
3D Printer ◽  
Topical Antibiotic ◽  
Young’S Moduli ◽  
Base Polymer ◽  
Potential Applications ◽  
3D Printed

AbstractThis study evaluates the suitability of 3D printed biodegradable mats to load and deliver the topical antibiotic, neomycin, for up to 3 weeks in vitro. A 3D printer equipped with a hot melt extruder was used to print bandage-like wound coverings with porous sizes appropriate for cellular attachment and viability. The semicrystalline polyester, poly-l-lactic acid (PLLA) was used as the base polymer, coated (post-printing) with polyethylene glycols (PEGs) of MWs 400 Da, 6 kDa, or 20 kDa to enable manipulation of physicochemical and biological properties to suit intended applications. The mats were further loaded with a topical antibiotic (neomycin sulfate), and cumulative drug-release monitored for 3 weeks in vitro. Microscopic imaging as well as Scanning Electron Microscopy (SEM) studies showed pore dimensions of 100 × 400 µm. These pore dimensions were achieved without compromising mechanical strength; because of the “tough” individual fibers constituting the mat (Young’s Moduli of 50 ± 20 MPa and Elastic Elongation of 10 ± 5%). The in vitro dissolution study showed first-order release kinetics for neomycin during the first 20 h, followed by diffusion-controlled (Fickian) release for the remaining duration of the study. The release of neomycin suggested that the ability to load neomycin on to PLLA mats increases threefold, as the MW of the applied PEG coating is lowered from 20 kDa to 400 Da. Overall, this study demonstrates a successful approach to using a 3D printer to prepare porous degradable mats for antibiotic delivery with potential applications to dermal regeneration and tissue engineering.

Automated calibration of 3D-printed microfluidic devices based on computer vision

2021 ◽  
Vol 15 (2) ◽  
pp. 024102
Author(s):  
Junchao Wang ◽  
Kaicong Liang ◽  
Naiyin Zhang ◽  
Hailong Yao ◽  
Tsung-Yi Ho ◽  
...  
Keyword(s):  
Computer Vision ◽  
Microfluidic Devices ◽  
Automated Calibration ◽  
3D Printed

P957Characteristics of atrial tachycardia after mitral surgey via biatrial trans-septal approach using high density mapping system

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
C Cataldi ◽  
M Andronache ◽  
R Eschalier ◽  
F Jean ◽  
R Bosle ◽  
...  
Keyword(s):  
Atrial Tachycardia ◽  
Sinus Node ◽  
Pulmonary Veins ◽  
High Density ◽  
Congenital Defects ◽  
Density Mapping ◽  
Mapping System ◽  
Oblique Incision ◽  
Pace Maker ◽  
The Right

Abstract Background The biatrial trans-septal approach (BTSa) ameliorates mitral valve (MV) exposure in difficult cases when routine left atriotomy doesnt"t allow it. Main steps are an oblique incision on the right atrium (RA), reaching medially the right pulmonary veins (PV), a septal incision from the fossa ovalis, extended up to reach the first incision, then on the left atrium (LA). Purpose We aim to study the arrhythmic burden in this post-surgical context, focusing on atrial tachycardia (AT), to investigate the complexity of several possible circuits. Methods All patients (&gt;18yo) with previous MV surgery via BTSa for MV repair or replacement, who underwent ablation of AT from January 2017 to September 2019, were enrolled. Patients ablated for persistent or paroxysmal AF, or with AF during the index procedure were excluded. Patients with associated surgery on other valves or congenital defects, coronary, surgical or percutaneous rhythm interventions weren’t excluded. Electroanatomical mapping was created using 2 different high-density mapping system. Substrate and activation map and radio-frequency (RF) ablation (25-50W, Ablation Index target 400) were realized. Cartographies were analysed to evaluate AT re-entry circuit, critical isthmus (CI) location and characterization, atrial vulnerability. Procedural outcomes (AT termination, sinus rhythm (SR) restoration, anti-arrhythmic drugs (AAD) withdrawal), and peri-procedural complications were also evaluated. Results We enrolled 49 patients (median age 57 ± 15), finding a maximum of 5 AT per procedure (2 ± 1). A total of 112 AT were mapped: the majority (72%) were persistent AT, 8,2% common atrial flutter. Cycle length was 314 ± 74 msec, with proximal-distal activation of coronary sinus (78%). A multiple re-entry circuit was observed in 70% of index AT. We identified 152 critical isthmus (maximum 5 per procedure). Only 27,9% of our patients had a single CI; CTI was the most frequent one (n = 37), envolved in 33% of all AT, while BTS scars altogether were envolved in 65% AT. A complete AT circuit was mapped in the RA, the LA and both atria in respectively 49%, 11,5% and 39%AT. The distribution of CIs is shown in figure 1. Biatrial and left AT leads to superior procedure, RF and fluoroscopy duration (p &lt;0,05). SR was restored in 93,4%of patients, requiring a DC shock in 4 cases. Immediate AAD withdrawal was achieved after 41%procedures. No pericardial, oesophageal, vascular or phrenic complication occurred. 4 pace-maker implantations were realized because of 3 interatrial, 2 AV block and a sinus node dysfunction. Conclusions AT occurring after a BTSa have a high prevalence of multiple re-entry circuits with multiple critical isthmus. Ablation in this context is feasible and safe but often requires a left atrial access. Mapping of both atria should be considered to identify critical isthmus and tailored ablation strategy. Abstract Figure 1. Critical Isthmus Distribution

Mechatronic Design of ARC Humanoid Robot Open Platform: First Fully 3D Printed Kid-Sized Robot

2020 ◽  
Vol 17 (03) ◽  
pp. 2050010
Author(s):  
Saeed Saeedvand ◽  
Hadi S. Aghdasi ◽  
Jacky Baltes
Keyword(s):  
Humanoid Robot ◽  
Size Range ◽  
Robot Design ◽  
3D Printer ◽  
Wide Angle ◽  
Open Platform ◽  
3D Printed ◽  
Wide Angle Camera ◽  
Computational Resources ◽  
User Friendly

Although there are several popular and capable humanoid robot designs available in the kid-size range, they lack some important characteristics: affordability, being user-friendly, using a wide-angle camera, sufficient computational resources for advanced AI algorithms, and mechanical robustness and stability are the most important ones. Recent advances in 3D printer technology enables researchers to move from model to physical implementation relatively easy. Therefore, we introduce a novel fully 3D printed open platform humanoid robot design named ARC. In this paper, we discuss the mechanical structure and software architecture. We show the capabilities of the ARC design in a series of experimental evaluations.

Preliminary Study of Alginates Extracted from Brown Algae (Sargassum sp.) Available in Madura Island as Composite Based Hydrogel Materials

2019 ◽  
Vol 964 ◽  
pp. 240-245 ◽  
Author(s):  
Amaliya Rasyida ◽  
Thalyta Rizkha Pradipta ◽  
Sigit Tri Wicaksono ◽  
Vania Mitha Pratiwi ◽  
Yeny Widya Rakhmawati
Keyword(s):  
Sodium Alginate ◽  
Brown Algae ◽  
Extraction Process ◽  
Composition Analysis ◽  
3D Printer ◽  
X Ray Diffraction ◽  
X Ray ◽  
3D Printed ◽  
Preliminary Study

Utilization of brown algae especially in Madura, where it’s close to Surabaya, only limited for food. This become a reference for developing and increasing the potential of this algae by extracting one of the ingredients, namely alginate. This paper deals with the characterization of sodium alginate extracted from sargassum sp. using modified-purified calcium routes. The extracted sodium alginate will be further used as composite hydrogel materials and compared with commercial sodium alginate. Hereafter, the synthesized composite is expected to be bio-ink for 3d printer. Chemical composition analysis were analyzed using X-Ray Fluorosense (XRF) followed by Fourier-transform infrared spectroscopy (FTIR) analysis to identify the functional group of composite and X-Ray Diffraction (XRD). Furthermore, viscosity bath is performed to compare the viscosity of extracted and commercial one. The result shows that modified-purified calcium routes in the extraction process of sodium alginate is desirable for improving their properties. Interestingly enough, with the goal of using it as bio-ink in 3d printed fabrication, the synthesized composite shows viscosity, 300 cSt, which meets the criteria for bio-ink in 3d printer.

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