A continuous roll-pulling approach for the fabrication of magnetic artificial cilia with microfluidic pumping capability

Lab on a Chip ◽  
2016 ◽  
Vol 16 (12) ◽  
pp. 2277-2286 ◽  
Author(s):  
Ye Wang ◽  
Jaap den Toonder ◽  
Ruth Cardinaels ◽  
Patrick Anderson
Keyword(s):  
Large Scale ◽  
Microfluidic Flow ◽  
Flow Generation ◽  
Artificial Cilia ◽  
Microfluidic Pumping

Magnetic artificial cilia capable of microfluidic flow generation fabricated using a novel roll pulling method with the potential for large-scale manufacturing.

scholarly journals Metachronal actuation of microscopic magnetic artificial cilia generates strong microfluidic pumping

Lab on a Chip ◽  
2020 ◽  
Vol 20 (19) ◽  
pp. 3569-3581
Author(s):  
Shuaizhong Zhang ◽  
Zhiwei Cui ◽  
Ye Wang ◽  
Jaap M. J. den Toonder
Keyword(s):  
Microfluidic Flow ◽  
Artificial Cilia ◽  
Microfluidic Pumping

Microscopic magnetic artificial cilia (μMAC) performing metachronal motion are experimentally demonstrated to generate unprecedented strong microfluidic flow.

scholarly journals The JGrass-NewAge system for forecasting and managing the hydrological budgets at the basin scale: models of flow generation and propagation/routing

2011 ◽  
Vol 4 (4) ◽  
pp. 943-955 ◽  
Author(s):  
G. Formetta ◽  
R. Mantilla ◽  
S. Franceschi ◽  
A. Antonello ◽  
R. Rigon
Keyword(s):  
Large Scale ◽  
Goodness Of Fit ◽  
Hydrological Modeling ◽  
Collaborative Work ◽  
Flow Equation ◽  
River Network ◽  
Predictive Capacity ◽  
Flow Generation ◽  
Basin Scale ◽  
Runoff Production

Abstract. This paper presents a discussion of the predictive capacity of the implementation of the semi-distributed hydrological modeling system JGrass-NewAge. This model focuses on the hydrological budgets of medium scale to large scale basins as the product of the processes at the hillslope scale with the interplay of the river network. The part of the modeling system presented here deals with the: (i) estimation of the space-time structure of precipitation, (ii) estimation of runoff production; (iii) aggregation and propagation of flows in channel; (v) estimation of evapotranspiration; (vi) automatic calibration of the discharge with the method of particle swarming. The system is based on a hillslope-link geometrical partition of the landscape, combining raster and vectorial treatment of hillslope data with vector based tracking of flow in channels. Measured precipitation are spatially interpolated with the use of kriging. Runoff production at each channel link is estimated through a peculiar application of the Hymod model. Routing in channels uses an integrated flow equation and produces discharges at any link end, for any link in the river network. Evapotranspiration is estimated with an implementation of the Priestley-Taylor equation. The model system assembly is calibrated using the particle swarming algorithm. A two year simulation of hourly discharge of the Little Washita (OK, USA) basin is presented and discussed with the support of some classical indices of goodness of fit, and analysis of the residuals. A novelty with respect to traditional hydrological modeling is that each of the elements above, including the preprocessing and the analysis tools, is implemented as a software component, built upon Object Modelling System v3 and jgrasstools prescriptions, that can be cleanly switched in and out at run-time, rather than at compiling time. The possibility of creating different modeling products by the connection of modules with or without the calibration tool, as for instance the case of the present modeling chain, reduces redundancy in programming, promotes collaborative work, enhances the productivity of researchers, and facilitates the search for the optimal modeling solution.

scholarly journals WAVE-GENERATED FLOWS ON THE WATER SURFACE

2016 ◽  
Vol 42 ◽  
pp. 1660179
Author(s):  
MICHAEL SHATS ◽  
HORST PUNZMANN ◽  
NICOLAS FRANCOIS ◽  
HUA XIA
Keyword(s):  
Water Surface ◽  
Large Scale ◽  
Three Dimensional ◽  
Surface Flow ◽  
Theoretical Problem ◽  
Complex Flows ◽  
Localized Source ◽  
New Methods ◽  
Flow Generation ◽  
Surface Jets

Predicting trajectories of fluid parcels on the water surface perturbed by waves is a difficult mathematical and theoretical problem. It is even harder to model flows generated on the water surface due to complex three-dimensional wave fields, which commonly result from the modulation instability of planar waves. We have recently shown that quasi-standing, or Faraday, waves are capable of generating horizontal fluid motions on the water surface whose statistical properties are very close to those in two-dimensional turbulence. This occurs due to the generation of horizontal vortices. Here we show that progressing waves generated by a localized source are also capable of creating horizontal vortices. The interaction between such vortices can be controlled and used to create stationary surface flows of desired topology. These results offer new methods of surface flow generation, which allow engineering inward and outward surface jets, large-scale vortices and other complex flows. The new principles can be also be used to manipulate floaters on the water surface and to form well-controlled Lagrangian coherent structures on the surface. The resulting flows are localized in a narrow layer near the surface, whose thickness is less than one wavelength.

Influence of non-monochromaticity on zonal-flow generation by magnetized Rossby waves in the ionospheric E-layer

2009 ◽  
Vol 75 (3) ◽  
pp. 345-357 ◽  
Author(s):  
T. D. KALADZE ◽  
H. A. SHAH ◽  
G. MURTAZA ◽  
L. V. TSAMALASHVILI ◽  
M. SHAD ◽  
...  
Keyword(s):  
Large Scale ◽  
Laboratory Experiments ◽  
Low Frequency ◽  
Zonal Flow ◽  
Present Theory ◽  
Resonant Interaction ◽  
Finite Amplitude ◽  
Small Scale ◽  
Zonal Flows ◽  
Flow Generation

AbstractThe influence of non-monochromaticity on low-frequency, large-scale zonal-flow nonlinear generation by small-scale magnetized Rossby (MR) waves in the Earth's ionospheric E-layer is considered. The modified parametric approach is used with an arbitrary spectrum of primary modes. It is shown that the broadening of the wave packet spectrum of pump MR waves leads to a resonant interaction with a growth rate of the order of the monochromatic case. In the case when zonal-flow generation by MR modes is prohibited by the Lighthill stability criterion, the so-called two-stream-like mechanism for the generation of sheared zonal flows by finite-amplitude MR waves in the ionospheric E-layer is possible. The growth rates of zonal-flow instabilities and the conditions for driving them are determined. The present theory can be used for the interpretation of the observations of Rossby-type waves in the Earth's ionosphere and in laboratory experiments.

scholarly journals Monitoring Serum Spike Protein with Disposable Photonic Biosensors Following SARS-CoV-2 Vaccination

Sensors ◽  
2021 ◽  
Vol 21 (17) ◽  
pp. 5857
Author(s):  
John S. Cognetti ◽  
Benjamin L. Miller
Keyword(s):  
Large Scale ◽  
Spike Protein ◽  
Label Free ◽  
Post Vaccination ◽  
Photonic Sensor ◽  
Microfluidic Flow ◽  
Sensor Platform ◽  
Patient Responses ◽  
Photonic Biosensors

While mRNA vaccines have been well-studied in vitro and in animals prior to their use in the human population during the Covid-19 pandemic, their exact mechanisms of inducing immunity are still being elucidated. The large-scale collection of data necessary to fully understand these mechanisms, and their variability across heterogeneous populations, requires rapid diagnostic tests that accurately measure the various biomarkers involved in the immune response following vaccination. Recently, our lab developed a novel “Disposable Photonics” platform for rapid, label-free, scalable diagnostics that utilizes photonic ring resonator sensor chips combined with plastic micropillar cards able to provide passive microfluidic flow. Here, we demonstrate the utility of this system in confirming the presence of SARS-CoV-2 spike protein in the serum of recently vaccinated subjects, as well as tracking a post-vaccination rise in anti-SARS-CoV-2 antibodies. A maximum concentration in SARS-CoV-2 spike protein was detected one day after vaccination and was reduced below detectable levels within 10 days. This highlights the applicability of our rapid photonic sensor platform for acquiring the data necessary to understand vaccine mechanisms on a large scale, as well as individual patient responses to SARS-CoV-2 mRNA vaccines.

scholarly journals The JGrass-NewAge system for forecasting and managing the hydrological budgets at the basin scale: the models of flow generation, propagation, and aggregation

2011 ◽  
Vol 4 (2) ◽  
pp. 943-969
Author(s):  
G. Formetta ◽  
R. Mantilla ◽  
S. Franceschi ◽  
A. Antonello ◽  
R. Rigon
Keyword(s):  
Large Scale ◽  
Goodness Of Fit ◽  
Hydrological Modeling ◽  
River Network ◽  
Basic Unit ◽  
Predictive Capacity ◽  
Scaling Properties ◽  
Flow Generation ◽  
Basin Scale ◽  
Runoff Production

Abstract. This paper presents a discussion of the predictive capacity of the first implementation of the semi-distributed hydrological modeling system JGrass-NewAge. This model focuses on the hydrological balance of medium scale to large scale basins, and considers statistics of the processes at the hillslope scale. The whole modeling system consists of six main parts: (i) estimation of energy balance; (ii) estimation of evapotranspiration; (iii) snow modelling; (iv) estimation of runoff production; (v) aggregation and propagation of flows in channel, and (vi) description of intakes, out-takes, and reservoirs. This paper details the processes, of runoff production, and aggregation/propagation of flows on a river network. The system is based on a hillslope-link geometrical partition of the landscape, so the basic unit, where the budget is evaluated, consists of hillslopes that drain into a single associated link rather than cells or pixels. To this conceptual partition corresponds an implementation of informatics that uses vectorial features for channels, and raster data for hillslopes. Runoff production at each channel link is estimated through a combination of the Duffy (1996) model and a GIUH model for estimating residence times in hillslope. Routing in channels uses equations integrated for any channels' link, and produces discharges at any link end, for any link in the river network. The model has been tested against measured discharges according to some indexes of goodness of fit such as RMSE and Nash Sutcliffe. The characteristic ability to reproduce discharge in any point of the river network is used to infer some statistics, and notably, the scaling properties of the modeled discharge.

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