Copolymerization of lactones and bioaromatics via concurrent ring-opening polymerization/polycondensation

2017 ◽  
Vol 19 (8) ◽  
pp. 1877-1888 ◽  
Author(s):  
Ha Thi Hoang Nguyen ◽  
Gabriel N. Short ◽  
Pengxu Qi ◽  
Stephen A. Miller
Keyword(s):  
Thermal Properties ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Random Copolymers ◽  
Hydroxy Acids

Concurrent ring-opening polymerization/polycondensation of lactones and bioaromatic hydroxy-acids yields random copolymers with improved and controlled thermal properties.

scholarly journals Controlled Ring-Opening Polymerization of O-Carboxyanhydrides to Synthesize Functionalized Poly(α-Hydroxy Acids)

2021 ◽  
Vol 03 (01) ◽  
pp. 041-050
Author(s):  
Xiaoqian Wang ◽  
Ai Lin Chin ◽  
Rong Tong
Keyword(s):  
Biomedical Engineering ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Metal Catalyst ◽  
Hydroxy Acids ◽  
Controlled Polymerization ◽  
Biodegradable Polyesters ◽  
Recent Advances

Poly(α-hydroxy acids), as a family of biodegradable polyesters, are valuable materials due to their broad applications in packaging, agriculture, and biomedical engineering. Herein we highlight and explore recent advances of catalysts in controlled ring-opening polymerization of O-carboxyanhydrides towards functionalized poly(α-hydroxy acids), especially metal catalyst-mediated controlled polymerization. Limitations of current polymerization strategies of O-carboxyanhydrides are discussed.

Biodegradable Polymers Derived from Amino Acids for Biological Applications

2010 ◽  
Vol 76 ◽  
pp. 30-35 ◽  
Author(s):  
Naomi Cohen-Arazi ◽  
Ilanit Hagag ◽  
Michal Kolitz ◽  
Abraham J. Domb ◽  
Jeoshua Katzhendler
Keyword(s):  
Amino Acids ◽  
Molecular Weight ◽  
Ring Opening ◽  
Building Blocks ◽  
Ring Opening Polymerization ◽  
Microwave Assisted Synthesis ◽  
Hydroxy Acids ◽  
Natural Amino Acids ◽  
Direct Condensation ◽  
Positively Charged

Optically active α-hydroxy acids derived from amino acids have been synthesized and polymerized into new biodegradable polyesters. The variety of functional side chains enables the design of positively charged, negatively charged, hydrophobic and hydrophilic chiral building blocks or any combination of these constituents. Hydroxy acids of 15 natural amino acids were prepared with retention of configuration using a straightforward and reliable method of diazotization of α-amino acids. Polyesters were synthesized from these hydroxy acids by a number of methods: direct condensation in bulk, microwave assisted synthesis and ring opening polymerization. The molecular weight of the prepared polymers ranges between 2000 to 5000Da for the direct condensation and the microwave methods, whereas the ring opening polymerization results in high molecular weight polymers (20000 to 30000Da). The polymers were analyzed for their optical activity (Circular Dichroism Spectroscopy), thermal properties (DSC), solubility, molecular weight and polydispersity (GPC), and aqueous degradation. These polymers were tested for their compatibility to neuronal cells growth and differentiation.

Thermal property of an aggregation-induced emission fluorophore that forms metal–ligand complexes with Zn(ClO4)2 of salicylaldehyde azine-functionalized polybenzoxazine

RSC Advances ◽  
2015 ◽  
Vol 5 (80) ◽  
pp. 65635-65645 ◽  
Author(s):  
Mohamed Gamal Mohamed ◽  
Ruey-Chorng Lin ◽  
Jia-Huei Tu ◽  
Fang-Hsien Lu ◽  
Jin-Long Hong ◽  
...  
Keyword(s):  
Thermal Properties ◽  
Thermal Property ◽  
Ring Opening ◽  
Zinc Ion ◽  
Ring Opening Polymerization ◽  
Aggregation Induced Emission ◽  
Metal Ligand

A salicylaldehyde azine-functionalized benzoxazine monomer formed zinc ion complexes not only improved the thermal properties but also facilitated ring-opening polymerization.

Development of a H3PW12O40/CeO2 catalyst for bulk ring-opening polymerization of a cyclic carbonate

2018 ◽  
Vol 20 (21) ◽  
pp. 4995-5006 ◽  
Author(s):  
Masayoshi Honda ◽  
Hideki Abe
Keyword(s):  
Thermal Properties ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Cyclic Carbonate

Various biomass-derived poly(aliphatic carbonate)s were synthesized by bulk ring-opening polymerization over a heterogeneous H3PW12O40/CeO2 catalyst, and thermal properties were investigated.

scholarly journals Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-l-serine Carboxyanhydrides

2012 ◽  
Vol 1 (4) ◽  
pp. 441-444 ◽  
Author(s):  
Yanbing Lu ◽  
Lichen Yin ◽  
Yanfeng Zhang ◽  
Zhonghai Zhang ◽  
Yunxiang Xu ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Hydroxy Acids ◽  
Soluble Poly

scholarly journals Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone)

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Yixiu Liu ◽  
Xizhuang Bai ◽  
A. Liang
Keyword(s):  
Ring Opening ◽  
Degradation Products ◽  
Hydrolytic Degradation ◽  
Ring Opening Polymerization ◽  
Random Copolymers ◽  
Thermal And Mechanical Properties ◽  
Degradation Rates ◽  
Synthesis Properties ◽  
Acidic Degradation

Random copolymers of poly(d,l-lactide-co-glycolide-co-ε-caprolactone) (PLGC) were synthesized by the ring-opening polymerization of d,l-lactide (DLLA), glycolide (GA), andε-caprolactone (CL). The effects of CL on the copolymers were evaluated to prepare suitable copolymers with controlled properties. Our results showed that the CL content significantly influenced the thermal and mechanical properties of the copolymers and that the CL content in compositions could be altered to control properties of random copolymers. The in vitro hydrolytic degradation of the resulting implants showed that the degradation rate of PLGC was lower than that of PLGA, which could markedly reduce acidic degradation products. Finally, we demonstrated that higher CL contents in compositions slowed degradation rates.

scholarly journals From Anionic Ring-Opening Polymerization of β-Butyrolactone to Biodegradable Poly(hydroxyalkanoate)s: Our Contributions in This Field

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4365
Author(s):  
Grażyna Adamus ◽  
Adrian Domiński ◽  
Marek Kowalczuk ◽  
Piotr Kurcok ◽  
Iza Radecka
Keyword(s):  
Ring Opening ◽  
Polymeric Materials ◽  
Ring Opening Polymerization ◽  
Random Copolymers ◽  
Acid Analogue ◽  
Biodegradable Poly ◽  
Anionic Ring ◽  
Synthetic Approaches ◽  
Hydroxybutanoic Acid ◽  
The Relationship

The feasibility of synthesis of functionalized poly(3-hydroxybutanoic acid) analogue and its copolymers via ring-opening polymerization of β-butyrolactone mediated by activated anionic initiators is presented. Using these new synthetic approaches, polyesters with a defined chemical structure of the end groups, as well as block, graft, and random copolymers, have been obtained and characterized by modern instrumental techniques, with special emphasis on ESI-MS. The relationship between the structure and properties of the prepared polymeric materials is also discussed.

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