scholarly journals The role of alternative testing strategies in environmental risk assessment of engineered nanomaterials

2017 ◽  
Vol 4 (2) ◽  
pp. 292-301 ◽  
Author(s):  
Rune Hjorth ◽  
Patricia A. Holden ◽  
Steffen Foss Hansen ◽  
Benjamin P. Colman ◽  
Khara Grieger ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Animal Testing ◽  
Test Systems ◽  
Testing Strategies ◽  
Alternative Testing ◽  
Alternative Testing Strategies

Within toxicology there is a pressure to find new test systems to replace, reduce and refine animal testing. In nanoecotoxicology this raises a number of questions.

Probabilistic modelling of engineered nanomaterial emissions to the environment: a spatio-temporal approach

2015 ◽  
Vol 2 (4) ◽  
pp. 340-351 ◽  
Author(s):  
Tian Yin Sun ◽  
Gulliver Conroy ◽  
Erica Donner ◽  
Konrad Hungerbühler ◽  
Enzo Lombi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Probabilistic Modelling ◽  
Environmental Concentrations ◽  
Engineered Nanomaterial ◽  
Spatio Temporal

For the environmental risk assessment of engineered nanomaterials (ENM) knowledge about environmental concentrations is crucial.

Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

2018 ◽  
Vol 5 (5) ◽  
pp. 1150-1160 ◽  
Author(s):  
Alicja Mikolajczyk ◽  
Agnieszka Gajewicz ◽  
Ewa Mulkiewicz ◽  
Bakhtiyor Rasulev ◽  
Martyna Marchelek ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Qsar Modeling ◽  
High Interest

The human health and environmental risk assessment of engineered nanomaterials (NPs) is nowadays of high interest.

scholarly journals Contribution of mesocosm testing to a single-step and exposure-driven environmental risk assessment of engineered nanomaterials

NanoImpact ◽  
2019 ◽  
Vol 13 ◽  
pp. 66-69 ◽  
Author(s):  
Mélanie Auffan ◽  
Armand Masion ◽  
Catherine Mouneyrac ◽  
Camille de Garidel-Thoron ◽  
Christine Ogilvie Hendren ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Single Step ◽  
Engineered Nanomaterials

scholarly journals Addressing a bottle neck for regulation of nanomaterials: quantitative read-across (Nano-QRA) algorithm for cases when only limited data is available

2017 ◽  
Vol 4 (2) ◽  
pp. 346-358 ◽  
Author(s):  
A. Gajewicz ◽  
K. Jagiello ◽  
M. T. D. Cronin ◽  
J. Leszczynski ◽  
T. Puzyn
Keyword(s):  
Experimental Data ◽  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
In Silico ◽  
Engineered Nanomaterials ◽  
Limited Data ◽  
Data Gaps ◽  
Bottle Neck

The development ofin silicomethods that support human health and environmental risk assessment of engineered nanomaterials is nowadays of high interest, because the application of those methods enables to fill the existing experimental data gaps.

scholarly journals Characterisation of Engineered Nanomaterials in Nano-Enabled Products Exhibiting Priority Environmental Exposure

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1370
Author(s):  
Raisibe Florence Lehutso ◽  
Yolanda Tancu ◽  
Arjun Maity ◽  
Melusi Thwala
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Real World ◽  
Environmental Risk Assessment ◽  
Total Concentration ◽  
Accurate Determination ◽  
Environmental Safety ◽  
Engineered Nanomaterials ◽  
Safety Guidelines

Analytical limitations have constrained the determination of nanopollution character from real-world sources such as nano-enabled products (NEPs), thus hindering the development of environmental safety guidelines for engineered nanomaterials (ENMs). This study examined the properties of ENMs in 18 commercial products: sunscreens, personal care products, clothing, and paints—products exhibiting medium to a high potential for environmental nanopollution. It was found that 17 of the products contained ENMs; 9, 3, 3, and 2 were incorporated with nTiO2, nAg, binaries of nZnO + nTiO2, and nTiO2 + nAg, respectively. Commonly, the nTiO2 were elongated or angular, whereas nAg and nZnO were near-spherical and angular in morphology, respectively. The size ranges (width × length) were 7–48 × 14–200, 34–35 × 37–38, and 18–28 nm for nTiO2, nZnO, and nAg respectively. All ENMs were negatively charged. The total concentration of Ti, Zn, and Ag in the NEPs were 2.3 × 10−4–4.3%, 3.4–4.3%, and 1.0 × 10−4–11.3 × 10−3%, respectively. The study determined some key ENM characteristics required for environmental risk assessment; however, challenges persist regarding the accurate determination of the concentration in NEPs. Overall, the study confirmed NEPs as actual sources of nanopollution; hence, scenario-specific efforts are recommended to quantify their loads into water resources.

Ecotoxicity Testing: Science, Politics and Ethics

2008 ◽  
Vol 36 (1) ◽  
pp. 103-112 ◽  
Author(s):  
Colin H. Walker
Keyword(s):  
Risk Assessment ◽  
European Union ◽  
Animal Welfare ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Assessment Procedure ◽  
The European Union ◽  
Testing Methods ◽  
Ecotoxicity Testing ◽  
Alternative Testing

Animal welfare organisations have long been concerned about the use of animals for ecotoxicity testing. Ecotoxicity testing is a necessary part of the statutory risk assessment of chemicals that may be released into the environment. It is sometimes also carried out during the development of new chemicals and in the investigation of pollution in the field. This review considers the existing requirements for ecotoxicity testing, with particular reference to practices in the European Union, including the recent REACH system proposals, before discussing criticisms that have been made of existing practices for environmental risk assessment. These criticisms have been made on scientific and ethical grounds, as well as on questions of cost. A case is made for greater investment in the development of alternative testing methods, which could improve the science, as well as serving the cause of animal welfare. It has frequently been suggested that the statutory requirements for environmental risk assessment are too rigid and bureaucratic. A case is made for flexibility and the greater involvement of scientists in the risk assessment procedure, in the interests of both improved science and improved animal welfare.

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