scholarly journals Addressing a bottle neck for regulation of nanomaterials: quantitative read-across (Nano-QRA) algorithm for cases when only limited data is available

2017 ◽  
Vol 4 (2) ◽  
pp. 346-358 ◽  
Author(s):  
A. Gajewicz ◽  
K. Jagiello ◽  
M. T. D. Cronin ◽  
J. Leszczynski ◽  
T. Puzyn
Keyword(s):  
Experimental Data ◽  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
In Silico ◽  
Engineered Nanomaterials ◽  
Limited Data ◽  
Data Gaps ◽  
Bottle Neck

The development ofin silicomethods that support human health and environmental risk assessment of engineered nanomaterials is nowadays of high interest, because the application of those methods enables to fill the existing experimental data gaps.

Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

2018 ◽  
Vol 5 (5) ◽  
pp. 1150-1160 ◽  
Author(s):  
Alicja Mikolajczyk ◽  
Agnieszka Gajewicz ◽  
Ewa Mulkiewicz ◽  
Bakhtiyor Rasulev ◽  
Martyna Marchelek ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Qsar Modeling ◽  
High Interest

The human health and environmental risk assessment of engineered nanomaterials (NPs) is nowadays of high interest.

scholarly journals The role of alternative testing strategies in environmental risk assessment of engineered nanomaterials

2017 ◽  
Vol 4 (2) ◽  
pp. 292-301 ◽  
Author(s):  
Rune Hjorth ◽  
Patricia A. Holden ◽  
Steffen Foss Hansen ◽  
Benjamin P. Colman ◽  
Khara Grieger ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Animal Testing ◽  
Test Systems ◽  
Testing Strategies ◽  
Alternative Testing ◽  
Alternative Testing Strategies

Within toxicology there is a pressure to find new test systems to replace, reduce and refine animal testing. In nanoecotoxicology this raises a number of questions.

scholarly journals Problem formulation for gene drive mosquitoes designed to reduce malaria transmission in Africa: results from four regional consultations 2016–2018

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
John L. Teem ◽  
Aggrey Ambali ◽  
Barbara Glover ◽  
Jeremy Ouedraogo ◽  
Diran Makinde ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Early Stage ◽  
Problem Formulation ◽  
Risk Assessments ◽  
Gene Drive ◽  
Starting Point ◽  
Protection Goals

Abstract Background Gene drive mosquitoes have been proposed as a possible means to reduce the transmission of malaria in Africa. Because this technology has no prior use-history at this time, environmental risk assessments for gene drive mosquitoes will benefit from problem formulation—an organized and ordered process to identify protection goals and potential pathways to harm to the environment, or animal or human health. Recognizing this need, the New Partnership for Africa’s Development (NEPAD), with support from African and international partners, organized four regional consultative workshops in Africa to initiate this process. Methods The workshops were attended by a diverse set of participants and stakeholders, including scientists, ethicists, health professionals, government regulators in the fields of environment health and biosafety as well government policymakers, who met for 4 days to deliberate on protection goals and pathways relevant to the use of gene drive mosquitoes for malaria control. The goal of the workshops was not to produce a comprehensive and detailed environmental risk assessment of gene drive mosquitoes, but rather to introduce problem formulation as a tool to the stakeholder community, and to serve as a starting point for conducting systematic environmental risk assessments in the future, identifying protection goals related to gene drive mosquitoes that are particular to African stakeholders. Results Participants in the workshops frequently identified human health and biodiversity as being relevant broad protection goals. Results of the deliberations provide insight into the concerns of African participants at an early stage in the development of gene drive organism/products that should be instructive to developers using this technology. Conclusions In general, the African participants of the consultations had a precautionary perspective with regard to environmental risk assessment of gene drive technology. As gene drive technology develops, protection goals will become further refined and candidate products will be further defined. These workshops represent only the beginning of a continuing process that will ultimately inform environmental risk assessment for gene drive mosquitoes to control malaria in Africa.

Probabilistic modelling of engineered nanomaterial emissions to the environment: a spatio-temporal approach

2015 ◽  
Vol 2 (4) ◽  
pp. 340-351 ◽  
Author(s):  
Tian Yin Sun ◽  
Gulliver Conroy ◽  
Erica Donner ◽  
Konrad Hungerbühler ◽  
Enzo Lombi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Probabilistic Modelling ◽  
Environmental Concentrations ◽  
Engineered Nanomaterial ◽  
Spatio Temporal

For the environmental risk assessment of engineered nanomaterials (ENM) knowledge about environmental concentrations is crucial.

scholarly journals Contribution of mesocosm testing to a single-step and exposure-driven environmental risk assessment of engineered nanomaterials

NanoImpact ◽  
2019 ◽  
Vol 13 ◽  
pp. 66-69 ◽  
Author(s):  
Mélanie Auffan ◽  
Armand Masion ◽  
Catherine Mouneyrac ◽  
Camille de Garidel-Thoron ◽  
Christine Ogilvie Hendren ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Single Step ◽  
Engineered Nanomaterials

Biomarkers and environmental risk assessment: Guiding principles from the human health field

2008 ◽  
Vol 56 (4) ◽  
pp. 613-619 ◽  
Author(s):  
Richard Owen ◽  
Tamara S. Galloway ◽  
Josephine A. Hagger ◽  
Malcolm B. Jones ◽  
Michael H. Depledge
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Guiding Principles ◽  
Health Field

scholarly journals Characterisation of Engineered Nanomaterials in Nano-Enabled Products Exhibiting Priority Environmental Exposure

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1370
Author(s):  
Raisibe Florence Lehutso ◽  
Yolanda Tancu ◽  
Arjun Maity ◽  
Melusi Thwala
Keyword(s):  
Risk Assessment ◽  
Environmental Risk ◽  
Real World ◽  
Environmental Risk Assessment ◽  
Total Concentration ◽  
Accurate Determination ◽  
Environmental Safety ◽  
Engineered Nanomaterials ◽  
Safety Guidelines

Analytical limitations have constrained the determination of nanopollution character from real-world sources such as nano-enabled products (NEPs), thus hindering the development of environmental safety guidelines for engineered nanomaterials (ENMs). This study examined the properties of ENMs in 18 commercial products: sunscreens, personal care products, clothing, and paints—products exhibiting medium to a high potential for environmental nanopollution. It was found that 17 of the products contained ENMs; 9, 3, 3, and 2 were incorporated with nTiO2, nAg, binaries of nZnO + nTiO2, and nTiO2 + nAg, respectively. Commonly, the nTiO2 were elongated or angular, whereas nAg and nZnO were near-spherical and angular in morphology, respectively. The size ranges (width × length) were 7–48 × 14–200, 34–35 × 37–38, and 18–28 nm for nTiO2, nZnO, and nAg respectively. All ENMs were negatively charged. The total concentration of Ti, Zn, and Ag in the NEPs were 2.3 × 10−4–4.3%, 3.4–4.3%, and 1.0 × 10−4–11.3 × 10−3%, respectively. The study determined some key ENM characteristics required for environmental risk assessment; however, challenges persist regarding the accurate determination of the concentration in NEPs. Overall, the study confirmed NEPs as actual sources of nanopollution; hence, scenario-specific efforts are recommended to quantify their loads into water resources.

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