scholarly journals Recent developments in reversible photoregulation of oligonucleotide structure and function

2017 ◽  
Vol 46 (4) ◽  
pp. 1052-1079 ◽  
Author(s):  
Anouk S. Lubbe ◽  
Wiktor Szymanski ◽  
Ben L. Feringa
Keyword(s):  
Rna Structure ◽  
Structure And Function ◽  
Dna And Rna ◽  
Recent Developments ◽  
And Function ◽  
Critical Overview

A critical overview is given of recent applications of molecular photoswitches to modulate DNA and RNA structure and function.

Applications of synthetic oligoribonucleotide analogues in studies of RNA structure and function

1994 ◽  
Vol 106 (5) ◽  
pp. 1003-1022
Author(s):  
Jane A. Grasby ◽  
Clare E. Pritchard ◽  
Michael J. Gait
Keyword(s):  
Rna Structure ◽  
Structure And Function ◽  
And Function

Insights into RNA structure and function from genome-wide studies

2014 ◽  
Vol 15 (7) ◽  
pp. 469-479 ◽  
Author(s):  
Stefanie A. Mortimer ◽  
Mary Anne Kidwell ◽  
Jennifer A. Doudna
Keyword(s):  
Rna Structure ◽  
Structure And Function ◽  
Genome Wide ◽  
And Function

The Molecular Mechanism of Photoinhibition — Facts and Fiction

1988 ◽  
Vol 15 (2) ◽  
pp. 27 ◽  
Author(s):  
C Critchley
Keyword(s):  
Photosystem Ii ◽  
Molecular Mechanism ◽  
Functional Group ◽  
Structure And Function ◽  
The Other ◽  
Proteolytic Degradation ◽  
Reaction Centre ◽  
Herbicide Binding ◽  
Recent Developments ◽  
And Function

In this paper, the evidence supporting two different models for the molecular mechanism of photoinhibition is discussed. One hypothesis centres around the suggestion that photoinhibition is due to the loss of the herbicide-binding Dl polypeptide of photosystem II. The other model suggests that damage to a functional group in the reaction centre is the primary cause of photoinhibition. In order to put the apparent controversy into context, recent developments in our understanding of the structure and function of the photosystem II reaction centre are described. Interpretation and judgement of all available evidence suggest primary photoinhibitory damage to be incurred by the reaction-centre chlorophyll P680 destabilising the apoprotein(s) and eventually resulting in their proteolytic degradation and removal from the photosystem II complex and the thylakoid membrane.

scholarly journals Computational design of three-dimensional RNA structure and function

2019 ◽  
Vol 14 (9) ◽  
pp. 866-873 ◽  
Author(s):  
Joseph D. Yesselman ◽  
Daniel Eiler ◽  
Erik D. Carlson ◽  
Michael R. Gotrik ◽  
Anne E. d’Aquino ◽  
...  
Keyword(s):  
Rna Structure ◽  
Three Dimensional ◽  
Computational Design ◽  
Structure And Function ◽  
And Function

scholarly journals Evidence for Hidden Involvement of N3-Protonated Guanine in RNA Structure and Function

ACS Omega ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 699-709 ◽  
Author(s):  
Antarip Halder ◽  
Saurabh Vemuri ◽  
Rohit Roy ◽  
Jayanth Katuri ◽  
Dhananjay Bhattacharyya ◽  
...  
Keyword(s):  
Rna Structure ◽  
Structure And Function ◽  
And Function

Neuroimaging: Clinical Applications

1998 ◽  
Vol 4 (6) ◽  
pp. 689-690
Author(s):  
Jarl Risberg
Keyword(s):  
Human Brain ◽  
Popular Literature ◽  
Clinical Applications ◽  
Structure And Function ◽  
Science Volume ◽  
Measurement Technology ◽  
Recent Developments ◽  
And Function ◽  
Further Development ◽  
The Brain

Imaging of the structure and function of the human brain has grown to an area with increasing impact on neuropsychological research as well as on the routine clinical evaluation of brain damaged patients. The scientific and popular literature is now flooded by increasingly more spectacular pictures of the brain. The images no longer only illustrate what is well known from earlier research but they do also sometimes provide information of importance for the further development of neuropsychological theories. The two volumes edited by Erin D. Bigler, Neuroimaging I and II, offer a possibility for neuropsychologists and other interested readers to get acquainted with the more recent developments in measurement technology and applications in basic science (Volume I) as well as in the clinic (Volume II). The authors of the 24 chapters are generally outstanding researchers, with impressive expertise within their fields of specialization.

Expanding the genetic code of mammalian cells

2017 ◽  
Vol 45 (2) ◽  
pp. 555-562 ◽  
Author(s):  
James S. Italia ◽  
Yunan Zheng ◽  
Rachel E. Kelemen ◽  
Sarah B. Erickson ◽  
Partha S. Addy ◽  
...  
Keyword(s):  
Protein Structure ◽  
Amino Acid ◽  
Mammalian Cells ◽  
Living Cells ◽  
Structure And Function ◽  
Unnatural Amino Acid ◽  
Full Potential ◽  
Recent Developments ◽  
Small Footprint ◽  
And Function

In the last two decades, unnatural amino acid (UAA) mutagenesis has emerged as a powerful new method to probe and engineer protein structure and function. This technology enables precise incorporation of a rapidly expanding repertoire of UAAs into predefined sites of a target protein expressed in living cells. Owing to the small footprint of these genetically encoded UAAs and the large variety of enabling functionalities they offer, this technology has tremendous potential for deciphering the delicate and complex biology of the mammalian cells. Over the last few years, exciting progress has been made toward expanding the toolbox of genetically encoded UAAs in mammalian cells, improving the efficiency of their incorporation and developing innovative applications. Here, we provide our perspective on these recent developments and highlight the current challenges that must be overcome to realize the full potential of this technology.

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