scholarly journals Novel fluorinated ligands for gold nanoparticle labelling with applications in 19F-MRI

2017 ◽  
Vol 53 (16) ◽  
pp. 2447-2450 ◽  
Author(s):  
Olatz Michelena ◽  
Daniel Padro ◽  
Carolina Carrillo-Carrión ◽  
Pablo del Pino ◽  
Jorge Blanco ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Fluorinated Ligands ◽  
19F Mri ◽  
Potential Applications

Novel fluorinated ligands for gold nanoparticle labelling and with potential applications in 19F-MRI have been designed and synthesised.

scholarly journals Gold Nanoparticle-Induced Cell Death and Potential Applications in Nanomedicine

2018 ◽  
Vol 19 (3) ◽  
pp. 754 ◽  
Author(s):  
Hainan Sun ◽  
Jianbo Jia ◽  
Cuijuan Jiang ◽  
Shumei Zhai
Keyword(s):  
Cell Death ◽  
Gold Nanoparticle ◽  
Potential Applications

scholarly journals Gold nanoparticle-doped silk film as biocompatible SERS substrate

RSC Advances ◽  
2015 ◽  
Vol 5 (3) ◽  
pp. 1937-1942 ◽  
Author(s):  
Chengchen Guo ◽  
Genevieve N. Hall ◽  
John B. Addison ◽  
Jeffery L. Yarger
Keyword(s):  
Gold Nanoparticle ◽  
Rapid Method ◽  
Biomedical Research ◽  
Sers Substrate ◽  
Potential Applications ◽  
Silk Films ◽  
Silk Film

In this work, we present a novel rapid method for fabricating biocompatible, biodegradable gold nanoparticle-embedded silk films (AuNP–silk films) that have potential applications in bioengineering and biomedical research.

Single Molecular Magnet - Gold Nanoparticle Composites

2009 ◽  
Vol 1198 ◽  
Author(s):  
Gopalan Balaji ◽  
Gudrun Bovenkamp ◽  
Vadim Palshin ◽  
Challa Kumar
Keyword(s):  
Gold Nanoparticle ◽  
Data Storage ◽  
Single Molecule ◽  
Composite Structures ◽  
Blocking Temperature ◽  
Molecular Magnet ◽  
Transition Elements ◽  
Single Molecule Magnets ◽  
Potential Applications ◽  
Ultrahigh Density

AbstractThe past decade has witnessed a great interest in single molecule magnets (SMM) especially those based on manganese such as Mn12-acetate due to their potential applications in ultrahigh density data storage and quantum computing devices. The focus so far has been in finding different derivatives of Mn or other complexes based on transition elements in order to raise the blocking temperature of single-molecule magnets (SMMs). Herein we propose a fundamentally new approach of generating new category of SMMs through formation of composite structures by binding SMMs on to nanoparticles. In this report, we present the synthesis and characterization of single molecular magnet - gold nanoparticle composite- Mn12-cysteinate functionalized gold nanoparticles.

scholarly journals Air-Filled Bubbles Stabilized by Gold Nanoparticle/Photodynamic Dye Hybrid Structures for Theranostics

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 415
Author(s):  
Roman Barmin ◽  
Polina Rudakovskaya ◽  
Olga Gusliakova ◽  
Olga Sindeeva ◽  
Ekaterina Prikhozhdenko ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Photoacoustic Imaging ◽  
Ultrasound Contrast Agents ◽  
Zinc Phthalocyanine ◽  
Hybrid Structures ◽  
Potential Applications ◽  
Average Size ◽  
The Impact ◽  
Potential Use

Microbubbles have already reached clinical practice as ultrasound contrast agents for angiography. However, modification of the bubbles’ shell is needed to produce probes for ultrasound and multimodal (fluorescence/photoacoustic) imaging methods in combination with theranostics (diagnostics and therapeutics). In the present work, hybrid structures based on microbubbles with an air core and a shell composed of bovine serum albumin, albumin-coated gold nanoparticles, and clinically available photodynamic dyes (zinc phthalocyanine, indocyanine green) were shown to achieve multimodal imaging for potential applications in photodynamic therapy. Microbubbles with an average size of 1.5 ± 0.3 μm and concentration up to 1.2 × 109 microbubbles/mL were obtained and characterized. The introduction of the dye into the system reduced the solution’s surface tension, leading to an increase in the concentration and stability of bubbles. The combination of gold nanoparticles and photodynamic dyes’ influence on the fluorescent signal and probes’ stability is described. The potential use of the obtained probes in biomedical applications was evaluated using fluorescence tomography, raster-scanning optoacoustic microscopy and ultrasound response measurements using a medical ultrasound device at the frequency of 33 MHz. The results demonstrate the impact of microbubbles’ stabilization using gold nanoparticle/photodynamic dye hybrid structures to achieve probe applications in theranostics.

scholarly journals Preparation of diamond-based AuNP-modified nanocomposites with elevated catalytic performances

RSC Advances ◽  
2017 ◽  
Vol 7 (79) ◽  
pp. 49923-49930 ◽  
Author(s):  
Xinna Zhao ◽  
Tifeng Jiao ◽  
Ruirui Xing ◽  
Hao Huang ◽  
Jie Hu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Catalytic Activity ◽  
Gold Nanoparticle ◽  
Nanocomposite Materials ◽  
Catalytic Material ◽  
Potential Applications ◽  
Catalytic Performances

Diamond@graphene oxide@gold nanoparticle (D@GO@AuNP) nanocomposite materials with excellent catalytic activity and high recyclability were prepared, demonstrating potential applications as a composite catalytic material.

Gold nanoparticles protected by fluorinated ligands for 19F MRI

2013 ◽  
Vol 49 (78) ◽  
pp. 8794 ◽  
Author(s):  
Mariangela Boccalon ◽  
Paola Franchi ◽  
Marco Lucarini ◽  
Juan José Delgado ◽  
Fernanda Sousa ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Fluorinated Ligands ◽  
19F Mri

scholarly journals Assessment of Altered Fucosylation of Serum α-1-Acid Glycoprotein in Hepatocellular Carcinoma Patients by Gold-Nanoparticle Aggregation Immunoassay

2018 ◽  
Vol 15 (3) ◽  
pp. 263-271
Author(s):  
Partha Pratim Bose ◽  
Urmimala Chatterjee ◽  
Bishnu Pada Chatterjee
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Plasmon Band ◽  
Acid Glycoprotein ◽  
Aleuria Aurantia Lectin ◽  
Gold Nanoparticle Aggregation ◽  
Potential Applications ◽  
Visual Assay ◽  
Protein Serum

Gold nanoparticles have attracted considerable attention due to their unique properties and potential applications as optical probes. When proteins that are adsorbed on gold nanoparticles subsequently get cross-linked by any interaction specific to that protein, the size of the aggregates increases and this enhancement of size have been used for sensitive, convenient and powerful tool to monitor the presence of the specific cross-linkers. Dynamic light scattering (DLS) is a technique that is routinely used for detecting aggregation in macromolecular solutions. In this work, we first applied DLS to identify specific glycoprotein–lectin interactions exclusively present in the serum of hepatocellular carcinoma patients compared to healthy controls that showed the altered fucosylation of a serum protein, Serum α-1-Acid glycoprotein. Further, based on the DLS data a simple, rapid, serological assay was developed based on antibody coated gold nanoparticle and fucose binding lectin (Aleuria aurantia lectin) as linker to asses the level of fucosylation of α-1-acid glycoprotein. As a consequence of the triggered aggregation of the GNP probes in presence of lectin, plasmon band was shifted from red to blue, which colorimetrically reported the enhanced fucosylation of α-1-acid glycoprotein and formed the basis of a rapid visual assay for hepatocellular carcinoma.

An in situ and ex situ TEM study of the formation of thin cobalt silicide films by molecular beam epitaxy on the silicon (100) surface

1988 ◽  
Vol 46 ◽  
pp. 884-885
Author(s):  
D. Loretto ◽  
J. M. Gibson ◽  
S. M. Yalisove ◽  
R. T. Tung
Keyword(s):  
Molecular Beam Epitaxy ◽  
Molecular Beam ◽  
Defect Density ◽  
High Vacuum ◽  
Ultra High Vacuum ◽  
Ex Situ ◽  
Metal Base ◽  
In Situ Experiments ◽  
Potential Applications

The cobalt disilicide/silicon system has potential applications as a metal-base and as a permeable-base transistor. Although thin, low defect density, films of CoSi2 on Si(111) have been successfully grown, there are reasons to believe that Si(100)/CoSi2 may be better suited to the transmission of electrons at the silicon/silicide interface than Si(111)/CoSi2. A TEM study of the formation of CoSi2 on Si(100) is therefore being conducted. We have previously reported TEM observations on Si(111)/CoSi2 grown both in situ, in an ultra high vacuum (UHV) TEM and ex situ, in a conventional Molecular Beam Epitaxy system.The procedures used for the MBE growth have been described elsewhere. In situ experiments were performed in a JEOL 200CX electron microscope, extensively modified to give a vacuum of better than 10-9 T in the specimen region and the capacity to do in situ sample heating and deposition. Cobalt was deposited onto clean Si(100) samples by thermal evaporation from cobalt-coated Ta filaments.

Microstructure of laser-irradiated, conducting Kapton polyimide

1995 ◽  
Vol 53 ◽  
pp. 502-503
Author(s):  
D. L. Callahan ◽  
Z. Ball ◽  
H. M. Phillips ◽  
R. Sauerbrey
Keyword(s):  
Electron Microscopy ◽  
Phase Transition ◽  
Transmission Electron Microscopy ◽  
Cross Section ◽  
Film Surface ◽  
Cross Sectional ◽  
General Utility ◽  
Transmission Electron ◽  
Considerable Debate ◽  
Potential Applications

Ultraviolet laser-irradiation can be used to induce an insulator-to-conductor phase transition on the surface of Kapton polyimide. Such structures have potential applications as resistors or conductors for VLSI applications as well as general utility electrodes. Although the percolative nature of the phase transformation has been well-established, there has been little definitive work on the mechanism or extent of transformation. In particular, there has been considerable debate about whether or not the transition is primarily photothermal in nature, as we propose, or photochemical. In this study, cross-sectional optical microscopy and transmission electron microscopy are utilized to characterize the nature of microstructural changes associated with the laser-induced pyrolysis of polyimide.Laser-modified polyimide samples initially 12 μm thick were prepared in cross-section by standard ultramicrotomy. Resulting contraction in parallel to the film surface has led to distortions in apparent magnification. The scale bars shown are calibrated for the direction normal to the film surface only.

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