scholarly journals G-Quadruplex formation using fluorescent oligonucleotides as a detection method for discriminating AGG trinucleotide repeats

2016 ◽  
Vol 52 (86) ◽  
pp. 12757-12760 ◽  
Author(s):  
Yoojin Park ◽  
Ki Tae Kim ◽  
Byeang Hyean Kim
Keyword(s):  
Detection Method ◽  
Oligonucleotide Probe ◽  
Trinucleotide Repeats ◽  
Enhanced Fluorescence ◽  
Background Signal ◽  
Low Background ◽  
G Quadruplex ◽  
Quadruplex Formation

A fluorescent oligonucleotide probe induces the formation of intermolecular G-quadruplexes with AGG trinucleotide repeats. The probe also exhibits 35.0- and 44.7-fold enhanced fluorescence signals for DNA AGG and RNA agg repeat oligonucleotides with respect to the low background signal.

Target-controlled gating liposome “off–on” cascade amplification for sensitive and accurate detection of phospholipase D in breast cancer cells with a low-background signal

2016 ◽  
Vol 52 (70) ◽  
pp. 10660-10663 ◽  
Author(s):  
Qingwang Xue ◽  
Wei Jiang ◽  
Lei Wang
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Phospholipase D ◽  
Breast Cancer Cells ◽  
Detection Method ◽  
Background Signal ◽  
Low Background ◽  
Accurate Detection ◽  
Cascade Amplification

Here we developed a simple, sensitive and accurate PLD detection method based on a target-controlled gating liposome (TCGL) “off–on” cascade amplified strategy and personal glucose meters (PGMs).

Label-free and sensitive detection of coralyne and heparin based on target-induced G-quadruplex formation

2019 ◽  
Vol 11 (10) ◽  
pp. 1331-1337 ◽  
Author(s):  
Mingjian Chen ◽  
Changbei Ma ◽  
Han Zhao ◽  
Kemin Wang
Keyword(s):  
Detection Method ◽  
Sensitive Detection ◽  
Label Free ◽  
G Quadruplex ◽  
Quadruplex Formation

Herein we propose a label-free and sensitive detection method for coralyne and heparin, based on utilizing the complex of adenosine16 (A16) and coralyne to induce the formation of a G-quadruplex scaffold.

Turn-on and label-free fluorescence detection of lead ions based on target-induced G-quadruplex formation

2015 ◽  
Vol 51 (38) ◽  
pp. 8165-8168 ◽  
Author(s):  
Lijun Xu ◽  
Xiaoqiang Shen ◽  
Shanni Hong ◽  
Jine Wang ◽  
Yuanyuan Zhang ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
High Sensitivity ◽  
Lead Ions ◽  
Label Free ◽  
Low Background ◽  
Background Fluorescence ◽  
Turn On ◽  
Sensing Systems ◽  
G Quadruplex ◽  
Quadruplex Formation

Using a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX (NMM), a turn-on and label-free fluorescent Pb2+ sensor with high sensitivity and low background fluorescence was presented as a representative of five turn-on sensing systems.

scholarly journals DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation

2013 ◽  
Vol 41 (22) ◽  
pp. 10323-10333 ◽  
Author(s):  
Justin D. Lormand ◽  
Noah Buncher ◽  
Connor T. Murphy ◽  
Parminder Kaur ◽  
Marietta Y. Lee ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Dna Polymerase Δ ◽  
G Quadruplex ◽  
Quadruplex Formation ◽  
Lagging Strand

scholarly journals TGF‐β‐induced fibrotic stress increases G‐quadruplex formation in human fibroblasts

FEBS Letters ◽  
2019 ◽  
Vol 593 (22) ◽  
pp. 3149-3161 ◽  
Author(s):  
Priyanka Toshniwal ◽  
Michelle Nguyen ◽  
Aurore Guédin ◽  
Helena Viola ◽  
Diwei Ho ◽  
...  
Keyword(s):  
Human Fibroblasts ◽  
G Quadruplex ◽  
Quadruplex Formation

Sensitive mutant DNA biomarker detection based on magnetic nanoparticles and nicking endonuclease assisted fluorescence signal amplification

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20020-20024 ◽  
Author(s):  
Na Li ◽  
Zhong Feng Gao ◽  
Bei Hua Kang ◽  
Nian Bing Li ◽  
Hong Qun Luo
Keyword(s):  
Magnetic Nanoparticles ◽  
Signal Amplification ◽  
Fluorescence Signal ◽  
Biomarker Detection ◽  
Background Signal ◽  
Sensitive Mutant ◽  
Nicking Endonuclease ◽  
Low Background ◽  
Target Dna ◽  
Fluorescence Signal Amplification

Amplified fluorescence target DNA detection was developed combining nicking endonuclease assisted target recycling and magnetic nanoparticles with low background signal.

Enzyme-Free Unlabeled DNA Logic Circuits Based on Toehold-Mediated Strand Displacement and Split G-Quadruplex Enhanced Fluorescence

2013 ◽  
Vol 25 (17) ◽  
pp. 2440-2444 ◽  
Author(s):  
Jinbo Zhu ◽  
Libing Zhang ◽  
Tao Li ◽  
Shaojun Dong ◽  
Erkang Wang
Keyword(s):  
Logic Circuits ◽  
Strand Displacement ◽  
Enhanced Fluorescence ◽  
G Quadruplex
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