scholarly journals Hybrid elastin-like recombinamer-fibrin gels: physical characterization and in vitro evaluation for cardiovascular tissue engineering applications

2016 ◽  
Vol 4 (9) ◽  
pp. 1361-1370 ◽  
Author(s):  
Israel Gonzalez de Torre ◽  
Miriam Weber ◽  
Luis Quintanilla ◽  
Matilde Alonso ◽  
Stefan Jockenhoevel ◽  
...  

In the field of tissue engineering, the properties of the scaffolds are of crucial importance for the success of the application.

Author(s):  
Jan-Eric W. Ahlfors ◽  
Kristen L. Billiar

Cell-seeded collagen and fibrin gels have been used extensively as in vitro wound healing models and for studying tissue remodeling. The have also been utilized as replacements for lost or damaged connective tissue [1]. The major drawback of these gel-based living tissue equivalents (LTEs) for tissue engineering applications is that they are not completely synthesized and arranged by the cells themselves, thus they are weak relative to native connective tissue.


F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 1045 ◽  
Author(s):  
George A. Truskey

Cardiovascular tissue engineering offers the promise of biologically based repair of injured and damaged blood vessels, valves, and cardiac tissue. Major advances in cardiovascular tissue engineering over the past few years involve improved methods to promote the establishment and differentiation of induced pluripotent stem cells (iPSCs), scaffolds from decellularized tissue that may produce more highly differentiated tissues and advance clinical translation, improved methods to promote vascularization, and novel in vitro microphysiological systems to model normal and diseased tissue function. iPSC technology holds great promise, but robust methods are needed to further promote differentiation. Differentiation can be further enhanced with chemical, electrical, or mechanical stimuli.


2013 ◽  
Vol 19 (4) ◽  
pp. 368-379 ◽  
Author(s):  
Jennifer Petsche Connell ◽  
Gulden Camci-Unal ◽  
Ali Khademhosseini ◽  
Jeffrey G. Jacot

ASAIO Journal ◽  
2002 ◽  
Vol 48 (1) ◽  
pp. 8-11 ◽  
Author(s):  
Stefan Jockenhoevel ◽  
Gregor Zund ◽  
Simon P. Hoerstrup ◽  
Andrea Schnell ◽  
Marco Turina

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