scholarly journals Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

The Analyst ◽  
2016 ◽  
Vol 141 (13) ◽  
pp. 3993-3996 ◽  
Author(s):  
Gunnar Dunér ◽  
Henrik Anderson ◽  
Zhichao Pei ◽  
Björn Ingemarsson ◽  
Teodor Aastrup ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Signal Enhancement ◽  
Interaction Studies ◽  
Receptor Interactions ◽  
Poly Acrylic Acid

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment.

Nanoassembled Thin Film Gas Sensors. III. Sensitive Detection of Amine Odors Using TiO2/Poly(acrylic acid) Ultrathin Film Quartz Crystal Microbalance Sensors

2010 ◽  
Vol 82 (6) ◽  
pp. 2228-2236 ◽  
Author(s):  
Seung-Woo Lee ◽  
Naoki Takahara ◽  
Sergiy Korposh ◽  
Do-Hyeon Yang ◽  
Kiyoshi Toko ◽  
...  
Keyword(s):  
Thin Film ◽  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Gas Sensors ◽  
Quartz Crystal ◽  
Ultrathin Film ◽  
Sensitive Detection ◽  
Poly Acrylic Acid

scholarly journals Interaction of Proteins with a Planar Poly(acrylic acid) Brush: Analysis by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D)

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 122
Author(s):  
Jacek Walkowiak ◽  
Michael Gradzielski ◽  
Stefan Zauscher ◽  
Matthias Ballauff
Keyword(s):  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Water Contact ◽  
Strong Adsorption ◽  
Ft Ir ◽  
Calorimetric Studies ◽  
Adsorption Desorption ◽  
Contact Angle Analysis ◽  
Poly Acrylic Acid

We describe the preparation of a poly(acrylic acid) (PAA) brush, polymerized by atom transfer radical polymerization (ATRP) of tert-butyl acrylate (tBA) and subsequent acid hydrolysis, on the flat gold surfaces of quartz-crystal microbalance (QCM) crystals. The PAA brushes were characterized by Fourier transform infrared (FT-IR) spectroscopy, ellipsometry and water contact angle analysis. The interaction of the PAA brushes with human serum albumin (HSA) was studied for a range of ionic strengths and pH conditions by quartz-crystal microbalance with dissipation monitoring (QCM-D). The quantitative analysis showed a strong adsorption of protein molecules onto the PAA brush. By increasing the ionic strength, we were able to release a fraction of the initially bound HSA molecules. This finding highlights the importance of counterions in the polyelectrolyte-mediated protein adsorption/desorption. A comparison with recent calorimetric studies related to the binding of HSA to polyelectrolytes allowed us to fully analyze the QCM data based on the results of the thermodynamic analysis of the binding process.

scholarly journals Hysteretic Swelling/Deswelling of Polyelectrolyte Brushes and Bilayer Films in Response to Changes in pH and Salt Concentration

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 812
Author(s):  
Nisha Hollingsworth ◽  
Ronald G. Larson
Keyword(s):  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Salt Concentration ◽  
Quartz Crystal ◽  
Ethylene Imine ◽  
Polyelectrolyte Brushes ◽  
Bilayer Films ◽  
Poly Ethylene ◽  
Poly Acrylic Acid

Abstract We use a quartz crystal microbalance with dissipation (QCM-D) to investigate the swelling/de-swelling and hysteresis in brushes of weakly ionizable polyanion poly(acrylic acid) (PAA) brushes and bilayers containing a PAA brush and a poly(ethylene imine) (PEI) overlayer [...]

Salt- and pH-induced swelling of a poly(acrylic acid) brush via quartz crystal microbalance w/dissipation (QCM-D)

Soft Matter ◽  
2019 ◽  
Vol 15 (39) ◽  
pp. 7838-7851 ◽  
Author(s):  
Nisha R. Hollingsworth ◽  
Sabina I. Wilkanowicz ◽  
Ronald G. Larson
Keyword(s):  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Swelling Behavior ◽  
Poly Acrylic Acid

Poly(arylic acid) brushes are thoroughly investigated using QCM-D to elucidate their swelling behavior in the presence of salt.

Polyethylene-co-acrylic Acid as Coating for Biosensor Application:  A Quartz Crystal Microbalance Study

Langmuir ◽  
2002 ◽  
Vol 18 (25) ◽  
pp. 9932-9936 ◽  
Author(s):  
Kok Ting Chong ◽  
Xiaodi Su ◽  
Edmund J. D. Lee ◽  
S. J. O'Shea
Keyword(s):  
Acrylic Acid ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Biosensor Application

A combined reflectometry and quartz crystal microbalance with dissipation setup for surface interaction studies

2008 ◽  
Vol 79 (7) ◽  
pp. 075107 ◽  
Author(s):  
Guoliang Wang ◽  
Michael Rodahl ◽  
Malin Edvardsson ◽  
Sofia Svedhem ◽  
Gabriel Ohlsson ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Surface Interaction ◽  
Interaction Studies
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