A fluorescent light-up probe based on AIE and ESIPT processes for β-galactosidase activity detection and visualization in living cells

2015 ◽  
Vol 3 (47) ◽  
pp. 9168-9172 ◽  
Author(s):  
Lu Peng ◽  
Meng Gao ◽  
Xiaolei Cai ◽  
Ruoyu Zhang ◽  
Kai Li ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Fluorescent Light ◽  
Galactosidase Activity ◽  
Activity Detection

A fluorescent probe with both AIE and ESIPT characteristics is developed for a β-galactosidase activity study in solution and living cells.

A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative

2017 ◽  
Vol 53 (32) ◽  
pp. 4505-4508 ◽  
Author(s):  
Guoyu Jiang ◽  
Guanjie Zeng ◽  
Wenping Zhu ◽  
Yongdong Li ◽  
Xiaobiao Dong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Detection ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Activity Detection

An AIE based tetraphenylethylene derivative (TPE-Gal) was designed for light-up fluorescence detection and imaging of β-galactosidase activity in living cells.

Hydroxyphenylquinazolinone-based turn-on fluorescent probe for β-galactosidase activity detection and application in living cells

2018 ◽  
Vol 156 ◽  
pp. 100-107 ◽  
Author(s):  
Wenge Yang ◽  
Xinxin Zhao ◽  
Jian Zhang ◽  
Yi Zhou ◽  
Shimin Fan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Activity Detection ◽  
Turn On

A hemicyanine-based colorimetric turn-on fluorescent probe for β-galactosidase activity detection and application in living cells

2019 ◽  
Vol 205 ◽  
pp. 310-317 ◽  
Author(s):  
Xinxin Zhao ◽  
Wenge Yang ◽  
Shimin Fan ◽  
Yi Zhou ◽  
Huace Sheng ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Activity Detection ◽  
Turn On

A sensitive two-photon ratiometric fluorescent probe for γ-glutamyltranspeptidase activity detection and imaging in living cells and cancer tissues

2018 ◽  
Vol 42 (7) ◽  
pp. 5403-5407 ◽  
Author(s):  
Wei Liu ◽  
Bo Huang ◽  
Zong-Xuan Tong ◽  
Shuanglong Wang ◽  
Yi-Jin Li ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Selective Detection ◽  
Activity Detection ◽  
Two Photon ◽  
Highly Sensitive ◽  
Cancer Tissues ◽  
Ratiometric Fluorescent Probe

We develop a novel ratiometric two-photon fluorescent probe that allows highly sensitive and selective detection and imaging of γ-glutamyltranspeptidase activities.

A universal fluorometric assay strategy for glycosidases based on functional carbon quantum dots: β-galactosidase activity detection in vitro and in living cells

2017 ◽  
Vol 5 (10) ◽  
pp. 1971-1979 ◽  
Author(s):  
Cong Tang ◽  
Jin Zhou ◽  
Zhaosheng Qian ◽  
Yanyan Ma ◽  
Yuanyuan Huang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Quantum Dots ◽  
Living Cells ◽  
Fluorometric Assay ◽  
Analytical Performance ◽  
Galactosidase Activity ◽  
Activity Detection ◽  
In Cells

A general assay strategy for glycosidase was developed based on functional CQDs, and the assay shows a good analytical performance in vitro and in cells.

A sensitive fluorescent probe for β-galactosidase activity detection and application in ovarian tumor imaging

2021 ◽  
Vol 9 (1) ◽  
pp. 170-175
Author(s):  
Fang Fan ◽  
Li Zhang ◽  
Xinguang Zhou ◽  
Fangya Mu ◽  
Guoyue Shi
Keyword(s):  
Fluorescent Probe ◽  
Ovarian Tumor ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Tumor Imaging ◽  
Ovarian Tumors ◽  
Galactosidase Activity ◽  
Activity Detection ◽  
Near Infrared Imaging

A sensitive fluorescent probe for β-galactosidase activity detection in vivo and near-infrared imaging of ovarian tumors by detecting β-gal.

Visualization of endogenous β-galactosidase activity in living cells and zebrafish with a turn-on near-infrared fluorescent probe

Talanta ◽  
2020 ◽  
Vol 217 ◽  
pp. 121098 ◽  
Author(s):  
Xiao Pang ◽  
Yaqian Li ◽  
Zile Zhou ◽  
Qiujun Lu ◽  
Ruihua Xie ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Turn On

In vivo ratiometric tracking of endogenous β-galactosidase activity using an activatable near-infrared fluorescent probe

2019 ◽  
Vol 55 (82) ◽  
pp. 12308-12311 ◽  
Author(s):  
Limin Shi ◽  
Chenxu Yan ◽  
Yiyu Ma ◽  
Ting Wang ◽  
Zhiqian Guo ◽  
...  
Keyword(s):  
Real Time ◽  
Fluorescent Probe ◽  
Nude Mice ◽  
Near Infrared ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Tumor Bearing ◽  
Real Time Tracking

Herein, we exemplify BODIPY-βgal as a ratiometric light-up NIR probe for the quantitative sensing of endogenous β-gal distribution in living cells, and real-time tracking of β-gal activity in tumor-bearing nude mice.

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