Thienoisoindigo (TIIG)-based small molecules for the understanding of structure–property–device performance correlations

2015 ◽  
Vol 3 (18) ◽  
pp. 9899-9908 ◽  
Author(s):  
Hyojin Kang ◽  
Su Yeon An ◽  
Bright Walker ◽  
Seyeong Song ◽  
Taehyo Kim ◽  
...  
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Organic Photovoltaics ◽  
Device Performance ◽  
Structure Property ◽  
End Capping

A series of small molecule semiconductors based on the recently conceived thienoisoindigo (TIIG) moiety and three end-capping moieties with varied electron-donating strength and conformations has been synthesized and utilized for organic photovoltaics (OPVs).

Control of the molecular orientation in small molecule-based organic photovoltaics

2020 ◽  
Vol 4 (10) ◽  
pp. 4934-4955
Author(s):  
Liang Wang ◽  
Shengwei Guo ◽  
Ke Zhou ◽  
Wei Ma
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Organic Photovoltaics ◽  
Molecular Orientation ◽  
Key Factors ◽  
Photovoltaic Properties ◽  
Orientation Control

Key factors that affect the orientation control of small molecules, as well as their effects on the photovoltaic properties, are discussed.

Side chain engineering in DTBDT-based small molecules for efficient organic photovoltaics

Nanoscale ◽  
2019 ◽  
Vol 11 (29) ◽  
pp. 13845-13852 ◽  
Author(s):  
Jisu Hong ◽  
Ji Young Choi ◽  
Kyunghun Kim ◽  
Nam-Suk Lee ◽  
Jiqiang Li ◽  
...  
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Organic Photovoltaics ◽  
Side Chain ◽  
Solvent Vapor ◽  
Vapor Annealing ◽  
Solvent Vapor Annealing

A new small-molecule donor with a DTBDT core exhibits apposite blend morphologies and a maximum PCE of 9.18% by side chain engineering and solvent vapor annealing.

scholarly journals Aromatic imide/amide-based organic small-molecule emitters for organic light-emitting diodes

2020 ◽  
Vol 4 (6) ◽  
pp. 1554-1568 ◽  
Author(s):  
Yuanyuan Qin ◽  
Guoping Li ◽  
Ting Qi ◽  
Hui Huang
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Light Emitting Diodes ◽  
Molecular Design ◽  
Organic Light Emitting Diodes ◽  
Device Performance ◽  
Design Rules ◽  
Light Emitting ◽  
The Past ◽  
Organic Light

Aromatic imide/amide-based organic small molecules as emitters in organic light-emitting diodes have caught increasing attention. This study summarized their advances in terms of device performance and molecular design rules over the past 20 years.

scholarly journals New cyclopentadithiophene (CDT) linked porphyrin donors with different end-capping acceptors for efficient small molecule organic solar cells

2017 ◽  
Vol 5 (19) ◽  
pp. 4742-4751 ◽  
Author(s):  
Susana Arrechea ◽  
Ana Aljarilla ◽  
Pilar de la Cruz ◽  
Manish Kumar Singh ◽  
Ganesh D. Sharma ◽  
...  
Keyword(s):  
Solar Cells ◽  
Small Molecules ◽  
Small Molecule ◽  
Organic Solar Cells ◽  
End Capping

Using cyclopentadithiophene as bridge in A–D–A porphyrin-based small molecules, and PC71BM as acceptor in BHJ solar cells PCE of 7.93%, is achieved after SVA.

Toward high performance indacenodithiophene-based small-molecule organic solar cells: investigation of the effect of fused aromatic bridges on the device performance

2016 ◽  
Vol 4 (6) ◽  
pp. 2252-2262 ◽  
Author(s):  
Jin-Liang Wang ◽  
Fei Xiao ◽  
Jun Yan ◽  
Kai-Kai Liu ◽  
Zheng-Feng Chang ◽  
...  
Keyword(s):  
Solar Cells ◽  
Small Molecules ◽  
Small Molecule ◽  
Organic Solar Cells ◽  
High Performance ◽  
Device Performance ◽  
Photovoltaic Properties

Here we report the synthesis of a pair of D1–A-bridge–D2-bridge–A–D1 type small molecules, which have different π-conjugated bridges and investigated the effects on their photovoltaic properties.

A privileged ternary blend enabling non-fullerene organic photovoltaics with over 14% efficiency

2020 ◽  
Vol 8 (43) ◽  
pp. 15135-15141
Author(s):  
Jing Yan ◽  
Yuan-Qiu-Qiang Yi ◽  
Jianqi Zhang ◽  
Huanran Feng ◽  
Yanfeng Ma ◽  
...  
Keyword(s):  
Small Molecule ◽  
Organic Photovoltaics ◽  
Power Conversion ◽  
Ternary Blend ◽  
Conversion Efficiencies

Two non-fullerene small molecule acceptors, NT-4F and NT-4Cl, were designed and synthesized. Power conversion efficiencies of 11.44% and 14.55% were achieved for NT-4Cl-based binary and ternary devices, respectively.

Copolymerization of urea and murexide for efficient photocatalytic hydrogen evolution and tetracycline degradation

2021 ◽  
Author(s):  
Zhilu Du ◽  
Xinyu Zhao ◽  
Yingnan Zhao ◽  
Huiying Sun ◽  
Yingqi Li ◽  
...  
Keyword(s):  
Small Molecules ◽  
Hydrogen Evolution ◽  
Effective Strategy ◽  
Structure Property ◽  
Photocatalytic Hydrogen Evolution ◽  
Property Relationship ◽  
Structure Property Relationship ◽  
Tetracycline Degradation ◽  
Depth Study

Copolymerization of urea and small molecules is an effective strategy to modify g-C3N4. To in-depth study the important effects of the introduction of small molecular moiety on the structure-property relationship...

scholarly journals STEM-20. A CANCER STEM CELL-SELECTIVE APOPTOSIS-INDUCING SMALL MOLECULE FOR THE TREATMENT OF GBM

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii200-ii200
Author(s):  
Stephen Skirboll ◽  
Natasha Lucki ◽  
Genaro Villa ◽  
Naja Vergani ◽  
Michael Bollong ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Small Molecules ◽  
Small Molecule ◽  
Large Scale ◽  
Critical Role ◽  
Tumor Formation ◽  
Cell Type ◽  
Caspase 1 ◽  
Activation Assay

Abstract INTRODUCTION Glioblastoma multiforme (GBM) is the most aggressive form of primary brain cancer. A subpopulation of multipotent cells termed GBM cancer stem cells (CSCs) play a critical role in tumor initiation and maintenance, drug resistance, and recurrence following surgery. New therapeutic strategies for the treatment of GBM have recently focused on targeting CSCs. Here we have used an unbiased large-scale screening approach to identify drug-like small molecules that induce apoptosis in GBM CSCs in a cell type-selective manner. METHODS A luciferase-based survival assay of patient-derived GBM CSC lines was established to perform a large-scale screen of ∼one million drug-like small molecules with the goal of identifying novel compounds that are selectively toxic to chemoresistant GBM CSCs. Compounds found to kill GBM CSC lines as compared to control cell types were further characterized. A caspase activation assay was used to evaluate the mechanism of induced cell death. A xenograft animal model using patient-derived GBM CSCs was employed to test the leading candidate for suppression of in vivo tumor formation. RESULTS We identified a small molecule, termed RIPGBM, from the cell-based chemical screen that induces apoptosis in primary patient-derived GBM CSC cultures. The cell type-dependent selectivity of RIPGBM appears to arise at least in part from redox-dependent formation of a proapoptotic derivative, termed cRIPGBM, in GBM CSCs. cRIPGBM induces caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex. In an intracranial GBM xenograft mouse model, RIPGBM was found to significantly suppress tumor formation. CONCLUSIONS Our chemical genetics-based approach has identified a small molecule drug candidate and a potential drug target that selectively targets cancer stem cells and provides an approach for the treatment of GBMs.

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