Nanoparticle stability in biologically relevant media: influence of polymer architecture

Soft Matter ◽  
2015 ◽  
Vol 11 (37) ◽  
pp. 7296-7307 ◽  
Author(s):  
Bethsy Adriana Aguilar-Castillo ◽  
Jose Luis Santos ◽  
Hanying Luo ◽  
Yanet E. Aguirre-Chagala ◽  
Teresa Palacios-Hernández ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
The Self ◽  
Media Influence ◽  
Poly Ethylene Glycol ◽  
Polymer Architecture ◽  
Biologically Relevant ◽  
Nanoparticle Stability ◽  
Poly Ethylene ◽  
Bottle Brush

We contrast the behavior of nanoparticles formed by the self-assembly of polymers based on poly(ethylene glycol) (PEG) and poly(d,l-lactide), with linear, linear-dendritic and bottle-brush architectures in biologically relevant media.

Utilization of click chemistry to study the effect of poly(ethylene)glycol molecular weight on the self-assembly of PEGylated gambogic acid nanoparticles for the treatment of rheumatoid arthritis

2020 ◽  
Vol 8 (16) ◽  
pp. 4626-4637 ◽  
Author(s):  
Anne Nguyen ◽  
Hidenori Ando ◽  
Roland Böttger ◽  
K. K. DurgaRao Viswanadham ◽  
Elham Rouhollahi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Molecular Weight ◽  
Ethylene Glycol ◽  
Click Chemistry ◽  
Self Assembly ◽  
The Self ◽  
Gambogic Acid ◽  
Poly Ethylene Glycol ◽  
Molecular Weights ◽  
Poly Ethylene

Click chemistry was used to study the effect of varied PEG molecular weights on the self-assembly of PEG-gambogic acid (GA) conjugates into nanoparticles.

scholarly journals Investigating the self-assembly and shape transformation of poly(ethylene glycol)-b-poly(d,l-lactide) (PEG-PDLLA) polymersomes by tailoring solvent-polymer interactions

2020 ◽  
Vol 11 (2) ◽  
pp. 275-280 ◽  
Author(s):  
Imke A. B. Pijpers ◽  
Fenghua Meng ◽  
Jan C. M. van Hest ◽  
Loai K. E. A. Abdelmohsen
Keyword(s):  
Ethylene Glycol ◽  
Organic Solvent ◽  
Self Assembly ◽  
Shape Change ◽  
Solvent Composition ◽  
The Self ◽  
Poly Ethylene Glycol ◽  
Shape Transformation ◽  
Polymer Interactions ◽  
Poly Ethylene

Different ratios between THF and dioxane were used to study the effect of organic solvent composition on the self-assembly and subsequent shape-change of poly(ethylene glycol)-b-poly(d,l-lactide) (PEG-PDLLA) polymersomes.

Polysarcosine: The Best Alternative of Poly (Ethylene Glycol)

2020 ◽  
Vol 04 ◽  
Author(s):  
Manu Singhai ◽  
Sankha Bhattacharya
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Protein Delivery ◽  
Ring Opening ◽  
Biomedical Applications ◽  
High Vacuum ◽  
Ring Opening Polymerization ◽  
Poly Ethylene Glycol ◽  
Biologically Relevant ◽  
Poly Ethylene

Abstract:: Polysarcosine (psar) is a non-ionic hydrophilic polypeptoid with numerous biologically relevant properties. Polysarcosine is poly (n-methylated glycine) and has been reported first by wesley and co-workers in the 1920s. Polysarcosine was first synthesized via ring-opening polymerization (rop) of sarcosine n-carboxyanhydride, using high-vacuum techniques. Overall, findings highlight the potential of poly(sarcosine) as an alternative corona-forming polymer to poly (ethylene glycol)-based analogues of (polymerization-induced self-assembly) pisa assemblies for use in various pharmaceutical and biomedical applications. Numerous studies suggested that such polypeptoids hold enormous potential for many biomedical applications, including protein delivery, colloidal stabilization, and nanomedicine.

Biodegradable poly(ethylene glycol)–poly(ε-carprolactone) polymeric micelles with different tailored topological amphiphilies for doxorubicin (DOX) drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (63) ◽  
pp. 58160-58172 ◽  
Author(s):  
Y. Chen ◽  
Y. X. Zhang ◽  
Z. F. Wu ◽  
X. Y. Peng ◽  
T. Su ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Polymeric Micelles ◽  
The Self ◽  
Molar Ratio ◽  
Poly Ethylene Glycol ◽  
Biodegradable Poly ◽  
Poly Ethylene

The self-assembly and drug release of the three PEG–PCL copolymers with different topologies but identical molar ratio between PEG to PCL.

Redox-responsive supramolecular amphiphiles constructed via host–guest interactions for photodynamic therapy

2015 ◽  
Vol 3 (8) ◽  
pp. 1218-1227 ◽  
Author(s):  
Feng Liu ◽  
Yufei Ma ◽  
Lei Xu ◽  
Lichao Liu ◽  
Weian Zhang
Keyword(s):  
Photodynamic Therapy ◽  
Ethylene Glycol ◽  
Disulfide Bond ◽  
Self Assembly ◽  
The Self ◽  
Poly Ethylene Glycol ◽  
Porphyrin Derivatives ◽  
Redox Responsive ◽  
Poly Ethylene ◽  
Supramolecular Amphiphiles

A supramolecular photosensitizer delivery system has been established through the self-assembly of supramolecular amphiphiles constructed by the host–guest interaction between poly(ethylene glycol)-β-cyclodextrin (PEG-β-CD) and adamantane-terminated porphyrin derivatives bearing a disulfide bond (TPPC6-SS-Ada).

SELF-ASSEMBLY MORPHOLOGIES AND ELECTRORHEOLOGICAL PROPERTIES OF POLYANILINE-POLY(ETHYLENE GLYCOL)- POLYANILINE TRIBLOCK COPOLYMERS

2007 ◽  
Vol 21 (28n29) ◽  
pp. 4961-4966
Author(s):  
HUI-RU MA ◽  
JIAN-GUO GUAN ◽  
RUN-ZHANG YUAN
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Solubility Parameter ◽  
Triblock Copolymers ◽  
The Self ◽  
Poly Ethylene Glycol ◽  
Polarization Rate ◽  
Poly Ethylene ◽  
Electrorheological Properties

The self-assembly properties and ER effects of the Polyaniline-Poly(ethylene glycol)-Polyaniline (PAn-PEG-PAn) triblock copolymers were studied in this paper. The results indicate that with the increase of solubility parameter of the solvent, PAn-PEG-PAn copolymers form into different morphologies of spheriods, vesicles and rods. PAn-PEG-PAn copolymers with vesicles morphology show the highest polarization strength, while those with rods have the most rapid polarization rate. Among the PAn-PEG-PAn copolymers of different morphologies, the PAn-PEG-PAn copolymer vesicles show the strongest ER effect.

Controlling the aggregation of sodium dodecylsulphate in aqueous poly(ethylene glycol) solutions

RSC Advances ◽  
2015 ◽  
Vol 5 (91) ◽  
pp. 74744-74752 ◽  
Author(s):  
J. Dey ◽  
N. Sultana ◽  
S. Kumar ◽  
V. K. Aswal ◽  
S. Choudhury ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
The Self ◽  
Poly Ethylene Glycol ◽  
Sodium Dodecylsulphate ◽  
Molecular Weights ◽  
Poly Ethylene

The role of PEG's of different molecular weights on the self-assembly of SDS and the role of added NaCl has been addressed opening new scopes for further studies.

scholarly journals Unusual Effect of Iodine Ions on the Self-Assembly of Poly(ethylene glycol)-Capped Gold Nanoparticles

Langmuir ◽  
2019 ◽  
Vol 36 (1) ◽  
pp. 311-317 ◽  
Author(s):  
Wenjie Wang ◽  
Hyeong Jin Kim ◽  
Wei Bu ◽  
Surya Mallapragada ◽  
David Vaknin
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
The Self ◽  
Poly Ethylene Glycol ◽  
Unusual Effect ◽  
Poly Ethylene

Effects of the molecular weight and the valency of guest-modified poly(ethylene glycol)s on the stability, size and dynamics of supramolecular nanoparticles

2015 ◽  
Vol 3 (34) ◽  
pp. 6945-6952 ◽  
Author(s):  
Carmen Stoffelen ◽  
Eugenio Staltari-Ferraro ◽  
Jurriaan Huskens
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
The Self ◽  
Pronounced Effect ◽  
Poly Ethylene Glycol ◽  
Size Stability ◽  
Supramolecular Nanoparticles ◽  
Poly Ethylene ◽  
The Stability

The length and valency of PEG-based stopper molecules have a pronounced effect on the self-assembly, size, stability and dynamics of supramolecular nanoparticles.

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