scholarly journals Self-assembling α,γ-cyclic peptides that generate cavities with tunable properties

2016 ◽  
Vol 7 (1) ◽  
pp. 183-187 ◽  
Author(s):  
Nuria Rodríguez-Vázquez ◽  
Rebeca García-Fandiño ◽  
Manuel Amorín ◽  
Juan R. Granja
Keyword(s):  
Cyclic Peptides ◽  
Design And Synthesis ◽  
Self Assembling ◽  
Tunable Properties

The design and synthesis of self-assembling cyclic peptides with tunable cavity properties is described, allowing the incorporation of guests with different features.

scholarly journals Design and synthesis of macromolecular structures from self-assembling building blocks

1995 ◽  
Vol 98 (1) ◽  
pp. 483-490
Author(s):  
J. L. M. van Nunen ◽  
A. P. H. J. Schenning ◽  
R. J. H. Hafkamp ◽  
C. F. van Nostrum ◽  
M. C. Feiters ◽  
...  
Keyword(s):  
Building Blocks ◽  
Design And Synthesis ◽  
Self Assembling

β3R3-Peptides: design and synthesis of novel peptidomimetics and their self-assembling properties at the air–water interface

2013 ◽  
Vol 11 (33) ◽  
pp. 5399 ◽  
Author(s):  
Simone Mosca ◽  
Claudia Dannehl ◽  
Uwe Möginger ◽  
Gerald Brezesinski ◽  
Laura Hartmann
Keyword(s):  
Water Interface ◽  
Design And Synthesis ◽  
Self Assembling ◽  
Air Water Interface

Molecular Pom Poms from Self-Assembling α,γ-Cyclic Peptides

2014 ◽  
Vol 20 (33) ◽  
pp. 10260-10265 ◽  
Author(s):  
Michele Panciera ◽  
Manuel Amorín ◽  
Juan R. Granja
Keyword(s):  
Cyclic Peptides ◽  
Self Assembling

Molecular Design and Synthesis of Artificial Ion Channels Based on Cyclic Peptides Containing Unnatural Amino Acids

2001 ◽  
Vol 66 (9) ◽  
pp. 2978-2989 ◽  
Author(s):  
Hitoshi Ishida ◽  
Zhi Qi ◽  
Masahiro Sokabe ◽  
Kiyoshi Donowaki ◽  
Yoshihisa Inoue
Keyword(s):  
Amino Acids ◽  
Ion Channels ◽  
Unnatural Amino Acids ◽  
Cyclic Peptides ◽  
Molecular Design ◽  
Design And Synthesis

scholarly journals Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

Molecules ◽  
2014 ◽  
Vol 19 (10) ◽  
pp. 15391-15407 ◽  
Author(s):  
Lei Wang ◽  
Nathalie Gagey-Eilstein ◽  
Sylvain Broussy ◽  
Marie Reille-Seroussi ◽  
Florent Huguenot ◽  
...  
Keyword(s):  
Cyclic Peptides ◽  
Design And Synthesis

scholarly journals Self-Assembling Cyclic Peptides:  Molecular Dynamics Studies of Dimers in Polar and Nonpolar Solvents†

2006 ◽  
Vol 110 (38) ◽  
pp. 18965-18972 ◽  
Author(s):  
Ekta Khurana ◽  
Steven O. Nielsen ◽  
Bernd Ensing ◽  
Michael L. Klein
Keyword(s):  
Molecular Dynamics ◽  
Cyclic Peptides ◽  
Nonpolar Solvents ◽  
Self Assembling

scholarly journals Stability and growth mechanism of self-assembling putative antifreeze cyclic peptides

2017 ◽  
Vol 19 (29) ◽  
pp. 19032-19042 ◽  
Author(s):  
Z. Faidon Brotzakis ◽  
Mascha Gehre ◽  
Ilja K. Voets ◽  
Peter G. Bolhuis
Keyword(s):  
Growth Mechanism ◽  
Cyclic Peptides ◽  
Cyclic Peptide ◽  
Growth Mechanisms ◽  
Self Assembling ◽  
Peptide Nanotube ◽  
Cyclic Peptide Nanotube

From right to left: three distinct growth mechanisms of a pentamer to a hexamer putative antifreeze cyclic peptide nanotube.

scholarly journals A contorted nanographene shelter

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Huang Wu ◽  
Yu Wang ◽  
Bo Song ◽  
Hui-Juan Wang ◽  
Jiawang Zhou ◽  
...  
Keyword(s):  
Excited States ◽  
Materials Science ◽  
Theoretical Calculations ◽  
Binding Affinities ◽  
Binding Mechanism ◽  
Comprehensive Investigation ◽  
Design And Synthesis ◽  
Self Assembling ◽  
Artificial Receptors ◽  
Trigonal Prismatic

AbstractNanographenes have kindled considerable interest in the fields of materials science and supramolecular chemistry as a result of their unique self-assembling and optoelectronic properties. Encapsulating the contorted nanographenes inside artificial receptors, however, remains challenging. Herein, we report the design and synthesis of a trigonal prismatic hexacationic cage, which has a large cavity and adopts a relatively flexible conformation. It serves as a receptor, not only for planar coronene, but also for contorted nanographene derivatives with diameters of approximately 15 Å and thicknesses of 7 Å. A comprehensive investigation of the host-guest interactions in the solid, solution and gaseous states by experimentation and theoretical calculations reveals collectively an induced-fit binding mechanism with high binding affinities between the cage and the nanographenes. Notably, the photostability of the nanographenes is improved significantly by the ultrafast deactivation of their excited states within the cage. Encapsulating the contorted nanographenes inside the cage provides a noncovalent strategy for regulating their photoreactivity.

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