Design of core–shell magnetic mesoporous silica hybrids for pH and UV light stimuli-responsive cargo release

RSC Advances ◽  
2016 ◽  
Vol 6 (35) ◽  
pp. 29106-29115 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Hak-Bong Kim ◽  
Jae-Ho Bae ◽  
Sun-Hee Kim ◽  
Chang-Sik Ha
Keyword(s):  
Targeted Delivery ◽  
Uv Light ◽  
Drug Carrier ◽  
Core Shell ◽  
Stimuli Responsive ◽  
Carrier System ◽  
Light Stimuli ◽  
Silica Hybrids ◽  
Drug Carrier System ◽  
Magnetic Mesoporous Silica

The drug carrier system proposed here efficiently works under UV light and pH triggers for controlled release of model cargoes. The nanocarrier can be used in the targeted delivery of cargoes by the ‘ON’ and ‘OFF’ command by the UV light trigger.

Targeted Delivery of Rolipram to the Liver Using Novel Drug Carrier System for the Treatment of Alcoholic Liver Disease

2017 ◽  
Vol 152 (5) ◽  
pp. S1114
Author(s):  
Walter Rodriguez-Alvarez ◽  
Jingwen Zhang ◽  
Gustavo Perez-Abadia ◽  
Craig J. McClain ◽  
Shirish Barve ◽  
...  
Keyword(s):  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Targeted Delivery ◽  
Drug Carrier ◽  
Carrier System ◽  
Drug Carrier System ◽  
Novel Drug

Improving the genistein oral bioavailability via its formulation into the metal–organic framework MIL-100(Fe)

2021 ◽  
Vol 9 (9) ◽  
pp. 2233-2239
Author(s):  
Adrià Botet-Carreras ◽  
Cristina Tamames-Tabar ◽  
Fabrice Salles ◽  
Sara Rojas ◽  
Edurne Imbuluzqueta ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Metal Organic Framework ◽  
Drug Carrier ◽  
Aqueous Solubility ◽  
Carrier System ◽  
System P ◽  
Metal Organic ◽  
Drug Carrier System ◽  
Organic Framework

Despite the interesting chemopreventive, antioxidant and antiangiogenic effects of the natural bioflavonoid genistein (GEN), its low aqueous solubility and bioavailability make it necessary to administer it using a suitable drug carrier system.

scholarly journals Light-triggered reversible disassembly of stimuli-responsive coordination metallosupramolecular Pd2L4 cages mediated by azobenzene-containing ligands

2019 ◽  
Vol 3 (6) ◽  
pp. 1238-1243 ◽  
Author(s):  
Shuang Fu ◽  
Quan Luo ◽  
Mingsong Zang ◽  
Jun Tian ◽  
Zherui Zhang ◽  
...  
Keyword(s):  
Uv Light ◽  
Light Irradiation ◽  
Stimuli Responsive ◽  
Uv Light Irradiation ◽  
Light Stimuli ◽  
Azo Ligand

A light-stimuli-responsive supramolecular azobenzene-containing M2L4 cage has been designed and synthesized. This cage can be reversibly disassembled/reassembled mediated by the azo-ligand under visible and UV light irradiation.

Functionalized Magnetic Nanoparticles for Selective Targeting of Cells

2008 ◽  
Vol 1140 ◽  
Author(s):  
Wolfgang Tremel ◽  
Mohammed Ibrahim Shukoor ◽  
Filipe Natalio ◽  
Muhammad Nawaz Tahir ◽  
Matthias Wiens ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Magnetic Nanoparticles ◽  
Drug Carrier ◽  
Optical Detection ◽  
Cpg Odn ◽  
Carrier System ◽  
Functionalized Magnetic Nanoparticles ◽  
Selective Targeting ◽  
Target Molecules ◽  
Drug Carrier System

ABSTRACTMnO nanoparticles were conjugated to single stranded DNA (ssDNA), Cytosin-phosphatidyl-Guanosin oligonucleotide (CpG ODN) to detect and activate Toll-like (TLR9) receptors in cells and to follow nanoparticle cellular trafficking by different means of imaging while at the same time serving as a drug carrier system. By virtue of their magnetic properties these nanoparticles may serve as vehicles for the transport of target molecules into cells, while the fluorescent target ligand allows optical detection simultaneously.x

Studies on a bioerodible drug carrier system based on polyphosphazene Part I. Synthesis

1986 ◽  
Vol 3 (1-4) ◽  
pp. 143-154 ◽  
Author(s):  
C.W.J. Grolleman ◽  
A.C. de Visser ◽  
J.G.C. Wolke ◽  
H. van der Goot ◽  
H. Timmerman
Keyword(s):  
Drug Carrier ◽  
Carrier System ◽  
Drug Carrier System
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