scholarly journals Design and development of a nanoemulsion system containing copper peptide by D-optimal mixture design and evaluation of its physicochemical properties

RSC Advances ◽  
2016 ◽  
Vol 6 (22) ◽  
pp. 17845-17856 ◽  
Author(s):  
Shazwani Samson ◽  
Mahiran Basri ◽  
Hamid Reza Fard Masoumi ◽  
Roghayeh Abedi Karjiban ◽  
Emilia Abdul Malek

The particle size of Virgin coconut oil nanoemulsions was optimized using D-optimal mixture design and the optimum formulation was physicochemically characterized.

Molecules ◽  
2014 ◽  
Vol 19 (7) ◽  
pp. 9187-9202 ◽  
Author(s):  
Yih Khor ◽  
Soo Koh ◽  
Kamariah Long ◽  
Shariah Long ◽  
Sharifah Ahmad ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0157737 ◽  
Author(s):  
Shazwani Samson ◽  
Mahiran Basri ◽  
Hamid Reza Fard Masoumi ◽  
Emilia Abdul Malek ◽  
Roghayeh Abedi Karjiban

Author(s):  
Alex Y ◽  
Roji George Roy

Biodiesel has become more attractive recently, because of its environmental benefits and the fact that it is made from renewable resources. Over the past few decades, most of the countries depending on diesel engines for transportation. Some of its valuable advantages like highest thermal efficiency made it very popular. At the same time, the cost of diesel fuel is increasing, due to the depletion of fossil fuels. In this current scenario, we need an alternative fuel instead of diesel fuel. Many of the researchers have successfully placed several works on generating energy from different types of alternative sources including solar and some kind of conversion processes including renewable agricultural products into liquid fuel. One of the biggest challenges for developing countries in relation to energy consumption is to develop and implement technologies that help to improve efficiency of automobile engines, also to reduce the emissions of harmful gases and particulate matters. In order to avoid environmental impacts, emissions are reduced or eliminated by introducing renewable energy resources. The present research chronicles the production and testing of renewable biodiesel fuel derived from virgin coconut oil on a diesel engine, to analyses the engine performance and emission characteristics. In the first phase of work, production of biodiesel fuel from virgin coconut oil using transeterification process with two types of catalysts (homogenous and heterogeneous). The preliminary results shows that, with the addition of homogenous catalyst called Potassium Hydroxide (KOH) with methanol shows much higher activity than that of heterogeneous catalysts, and it shows more similar properties with diesel fuel. The results obtained from the chemical test and physicochemical properties of transesterified biodiesel fuel clearly proves the above-mentioned statement. The chemical tests such as GCMS and FT-IR clearly shows that the biodiesel fuel has sufficient amount of volatile components and functional groups. Then, physicochemical properties include, Fire point, Flashpoint, density, and viscosity were analyzed. Finally, Engine performance and Emission characteristics were analysed to confirm, whether this biodiesel fuel is suitable for diesel engines, without any engine modifications. It was found to be, the transesterified virgin coconut oil biodiesel has similar properties to that of the diesel fuel. From the physiochemical properties and engine performance clearly shows that, coconut oil biodiesel is suitable for diesel engine on blending, at a blending percentage level of 20% with conventional diesel fuel. Since the obtained transesterified biofuel can be used as an alternative fuel for diesel engines. The several journal reports and find outs from experimental investigation clearly depicts that the efficiency of the transesterified biofuel mainly depends upon the amount of catalyst adding and type of catalysts present in the biofuel, whether it is homogenous or heterogeneous catalyst is suitable with methanol. Finally, from the analysis made from biodiesel fuel. Coconut Oil Biodiesel fuel has less emission characteristics than that of the diesel fuels.


2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Silvi Putri Irawati ◽  
Dina Rahmawanty ◽  
Mia Fitriana

ABSTRAK Minyak nilam (Pogostemon cablin Benth.) mengandung patchouli alcohol yang berpotensi sebagai antioksidan. Pembuatan mikroemulsi dapat membantu minyak nilam menembus lapisan kulit untuk menghindari kerutan pada kulit. Mikroemulsi terdiri dari surfaktan, kosurfaktan, minyak dan air. Polisorbat 80 digunakan sebagai surfaktan yang apabila dikombinasikan dengan VCO akan membentuk ukuran globul mikroemulsi yang kecil. Sorbitol sebagai kosurfaktan untuk membantu menurunkan tegangan antarmuka. Tujuan penelitian ini untuk menetapkan konsentrasi Virgin Coconut Oil (VCO), polisorbat 80 dan sorbitol yang dapat diformulasikan sebagai sediaan mikroemulsi minyak nilam yang memenuhi karaketristik fisik yang baik. Karakterisasi dilakukan dengan pengujian organoleptis, ukuran partikel, tipe emulsi, bobot jenis, pH, viskositas dan uji stabilitas mekanik dengan sentrifugasi. Hasil pengamatan menunjukkan formula mikroemulsi yang optimum adalah F1 dengan komponen 1,96%b/b VCO, 15,68%b/b polisorbat 80, dan 1,96%b/b sorbitol. Mikroemulsi minyak nilam secara organoleptis tidak berwarna, beraroma nilam dan transparan. Ukuran partikel yang diperoleh yaitu 4,691±0,08 µm, tipe mikroemulsi adalah tipe M/A, bobot jenis sebesar 1,0278±0,0004, nilai pH yaitu 7,273±0,015 dan nilai viskositas adalah 15cPs. Hasil uji sentrifugasi menunjukkan sediaan mikroemulsi transparan dan tidak terjadi pemisahan fase. Kesimpulannya adalah konsentrasi VCO, polisorbat 80 dan sorbitol pada F1 dapat diformulasikan sediaan mikroemulsi yang memenuhi sifat fisik yang baik. Kata kunci: minyak nilam, mikroemulsi, VCO, polisorbat 80, sorbitol ABSTRACT Patchouli oil (Pogostemon cablin Benth.) containing patchouli alcohol that has potential antioxidant effect. Patchouli oil have to be formulated in microemulsion dosage forms to increase the stability and to help its penetration through human skin. Microemulsion consisting of surfactant, co-surfactant, oil and water. Polysorbate 80 was used as surfactant, the combine of polysorbate 80 and VCO can produce smaller microemulsion globule. Sorbitol was used as co-surfactant to help decrease interfacial tension. The purpose of this study was to assign the concentration of Virgin Coconut Oil (VCO), polysorbate 80 and sorbitol that could be processed as microemulsion of patchouli oil which had the best characteristic. The microemulsion characterization were includes organoleptic test, particle size measurement, specific gravity, type of emulsion, pH, viscosity and mechanical stability with centrifugation test. The results of observations showed that optimum formula was F1 with 1.96%w/w VCO, 15.68%w/w polysorbate 80, and 1.96%w/w sorbitol. This formula had clear, colorless organoleptic, and aromatic patchouli oil. The average particle size was 4.691±0.08 µm, the type of microemulsion was o/w, the specific gravity was 1,0278±0,0004, pH 7,273±0,015 and theviscosity was 15cPs. The microemulsion was stable with centrifugation test. The conclusion of this study was the microemulsion could be made by F1 formula. Keywords: patchouli oil, microemulsions, VCO, polysorbate 80, sorbitol


2018 ◽  
Vol 6 (5) ◽  
pp. 1298-1306 ◽  
Author(s):  
Nurul Aqilah A. Ghani ◽  
Amy-Arniza Channip ◽  
Phoebe Chok Hwee Hwa ◽  
Fairuzeta Ja'afar ◽  
Hartini M. Yasin ◽  
...  

2018 ◽  
Vol 23 (1) ◽  
pp. 40
Author(s):  
Wira Noviana Suhery ◽  
Mira Febrina ◽  
Ivone Permatasari

Research on micro emulsion formulation of combination of virgin coconut oil (VCO) and rice bran oil (RBO) as a hair growth promoter has been done. The purpose of this study was to formulate and produce the best formula that is physically stable and optimally promoting the hair growth by varying the content of VCO and RBO in the form of micro emulsions. These dosage formulations were prepared in three formulas using 45% tween 80 as surfactants and 20% glycerin as co surfactant i.e.: F,I containing a combination of VCO and RBO 1:1; FII (1:2) and FIII (2:1). Physical evaluation of the preparation was carried out for 8 weeks of storage which included organoleptic examination, pH, homogeneity, density, globule particle size, phase freeze thaw, and rabbit hair growth activity test for 18 days. Based on the results of the evaluation, it was found that the FI, FII and FIII micro emulsion formulations were physically stable for 8 weeks of storage with a pH ranging from 6.7 to 7.0, density of 1.085-1.088 g/mL, average globul particle size of FI (34.6 nm ), FII (54 nm) and FIII (68.8 nm). The best formulas is FIII for hair growth length of 1.26 cm for 18 days.


2019 ◽  
Vol 37 (1) ◽  
pp. 46-66 ◽  
Author(s):  
Abdul Rohman ◽  
Irnawati ◽  
Yuny Erwanto ◽  
Endang Lukitaningsih ◽  
Muhamad Rafi ◽  
...  

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