Stability behaviour of antiretroviral drugs and their combinations. 1: characterization of tenofovir disoproxil fumarate degradation products by mass spectrometry

RSC Advances ◽  
2015 ◽  
Vol 5 (116) ◽  
pp. 96117-96129 ◽  
Author(s):  
Moolchand Kurmi ◽  
Vijaya Madhyanapu Golla ◽  
Sanjay Kumar ◽  
Archana Sahu ◽  
Saranjit Singh
Keyword(s):  
Mass Spectrometry ◽  
Tenofovir Disoproxil Fumarate ◽  
Degradation Products ◽  
Antiretroviral Drugs ◽  
Degradation Behaviour ◽  
Stability Behaviour ◽  
Intrinsic Degradation

The investigation established the intrinsic degradation behaviour of tenofovir disoproxil fumarate in solid and solution states.

Forced degradation of lafutidine and characterization of its non-volatile and volatile degradation products using LC-MS/TOF, LC-MSn and HS-GC-MS

2015 ◽  
Vol 39 (12) ◽  
pp. 9679-9692 ◽  
Author(s):  
Shah Kinalkumar Pravinchandra ◽  
Moolchand Kurmi ◽  
Sanjay Kumar ◽  
Saranjit Singh
Keyword(s):  
Degradation Products ◽  
Forced Degradation ◽  
Degradation Behaviour ◽  
Intrinsic Degradation

The study involved establishment of the intrinsic degradation behaviour of lafutidine under hydrolytic, oxidative and photolytic conditions.

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