Process characterization of epithelial–mesenchymal transition in alveolar epithelial type II cells using surface-enhanced Raman scattering spectroscopy

RSC Advances ◽  
2016 ◽  
Vol 6 (17) ◽  
pp. 14321-14328 ◽  
Author(s):  
Xiaowei Cao ◽  
Xiang Chen ◽  
Chaowen Shi ◽  
Mingyue Zhang ◽  
Wenbo Lu ◽  
...  

Here we present a sensitive, non-invasive, and label-free detection method for successful identification and discrimination of the BLM-induced EMT in ATII cells, which is based on the TAT-functionalized AuNSs as intracellular SERS probes.

RSC Advances ◽  
2019 ◽  
Vol 9 (23) ◽  
pp. 13304-13315 ◽  
Author(s):  
Xiaowei Cao ◽  
Shuai Chen ◽  
Zhenyu Wang ◽  
Yong Liu ◽  
Xiaowei Luan ◽  
...  

A AuNPs–AgNWs decorated silicon wafer was used as a non-destructive and label-free tool in SERS spectroscopy to detect and distinguish the cellular composition of CYP2C9-expressing cells (293T-Mig-2C9) and non-expressing cells (293T-Mig-R1).


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