Manipulation of silver nanoparticles in a droplet for label-free detection of biological molecules using surface-enhanced Raman scattering

Author(s):  
Mustafa Çulha ◽  
Mine Altunbek ◽  
Sercan Keskin ◽  
Deniz Saatçi
RSC Advances ◽  
2019 ◽  
Vol 9 (23) ◽  
pp. 13304-13315 ◽  
Author(s):  
Xiaowei Cao ◽  
Shuai Chen ◽  
Zhenyu Wang ◽  
Yong Liu ◽  
Xiaowei Luan ◽  
...  

A AuNPs–AgNWs decorated silicon wafer was used as a non-destructive and label-free tool in SERS spectroscopy to detect and distinguish the cellular composition of CYP2C9-expressing cells (293T-Mig-2C9) and non-expressing cells (293T-Mig-R1).


2020 ◽  
Vol 15 (11) ◽  
pp. 1321-1326
Author(s):  
Aning Ma ◽  
Wenjing Wei ◽  
Zhongqiang Zhang ◽  
Sichang Peng ◽  
Yurong Wang ◽  
...  

An efficient surface-enhanced Raman scattering substrate based on silver nanoparticles/silicon pyramid arrays structure is theoretically investigated and experimentally demonstrated. The electric field distributions using finite-element-method are calculated. The surface-enhanced Raman scattering behaviors of sensitivity, uniformity and stability are emphatically discussed and compared by the detection of crystal violet. These theoretical and experimental results reveal that the silver nanoparticles/silicon pyramid arrays substrate is expected to be an effective surface-enhanced Raman scattering platform for label-free sensitive surfaceenhanced Raman spectroscopy detection in areas of biotechnology, medicine and food safety.


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