Paramagnetic, pH and temperature-sensitive polymeric particles for anticancer drug delivery and brain tumor magnetic resonance imaging

RSC Advances ◽  
2015 ◽  
Vol 5 (106) ◽  
pp. 87512-87520 ◽  
Author(s):  
Ruiqing Liu ◽  
Shuang Liang ◽  
Cun Jiang ◽  
Xin Wang ◽  
Ying Gong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Anticancer Drug ◽  
Temperature Sensitive ◽  
Resonance Imaging ◽  
Anticancer Drug Delivery ◽  
Polymeric Particles

Dually responsive polymeric particles for brain tumor (glioma) MR imaging and anticancer drug delivery.

Luminescent magnetic hollow mesoporous silica nanotheranostics for camptothecin delivery and multimodal imaging

2014 ◽  
Vol 2 (24) ◽  
pp. 3799-3808 ◽  
Author(s):  
Swagatika Sahu ◽  
Niharika Sinha ◽  
Sujit K. Bhutia ◽  
Megharay Majhi ◽  
Sasmita Mohapatra
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Contrast Agent ◽  
Anticancer Drug ◽  
Multimodal Imaging ◽  
Resonance Imaging ◽  
Anticancer Drug Delivery ◽  
Hollow Mesoporous Silica

The synthesis of a novel and specific nanoplatform for anticancer drug delivery, fluorescence imaging and contrast agent in magnetic resonance imaging has been described.

Correlation of the relationships of brain—tumor interfaces, magnetic resonance imaging, and angiographic findings to predict cleavage of meningiomas

1999 ◽  
Vol 91 (3) ◽  
pp. 384-390 ◽  
Author(s):  
Faruk İldan ◽  
Metin Tuna ◽  
Alp İskender Göcer ◽  
Bülent Boyar ◽  
Hüseyin Bağdatoğlu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Vascular Supply ◽  
Peritumoral Edema ◽  
Resonance Imaging ◽  
Content Type ◽  
Angiographic Findings ◽  
Fine Print

Object. The authors examined the relationships of brain—tumor interfaces, specific magnetic resonance (MR) imaging features, and angiographic findings in meningiomas to predict tumor cleavage and difficulty of resection.Methods. Magnetic resonance imaging studies, angiographic data, operative reports, clinical data, and histopathological findings were examined retrospectively in this series, which included 126 patients with intracranial meningiomas who underwent operations in which microsurgical techniques were used. The authors have identified three kinds of brain—tumor interfaces characterized by various difficulties in microsurgical dissection: smooth type, intermediate type, and invasive type. The signal intensity on T1-weighted MR images was very similar regardless of the type of brain—tumor interface (p > 0.1). However, on T2-weighted images the different interfaces seemed to correlate very precisely with the signal intensity and the amount of peritumoral edema (p < 0.01), allowing the prediction of microsurgical effort required during surgery. On angiographic studies, the pial—cortical arterial supply was seen to participate almost equally with the meningeal—dural arterial supply in vascularizing the tumor in 57.9% of patients. Meningiomas demonstrating hypervascularization on angiography, particularly those fed by the pial—cortical arteries, exhibited significantly more severe edema compared with those supplied only from meningeal arteries (p < 0.01). Indeed, a positive correlation was found between the vascular supply from pial—cortical arteries and the type of cleavage (p < 0.05).Conclusions. In this analysis the authors proved that there is a strong correlation between the amount of peritumoral edema, hyperintensity of the tumor on T2-weighted images, cortical penetration, vascular supply from pial—cortical arteries, and cleavage of the meningioma. Therefore, the consequent difficulty of microsurgical dissection can be predicted preoperatively by analyzing MR imaging and angiographic studies.

Magnetic nanoscale metal organic frameworks for potential targeted anticancer drug delivery, imaging and as an MRI contrast agent

2016 ◽  
Vol 45 (7) ◽  
pp. 2963-2973 ◽  
Author(s):  
Angshuman Ray Chowdhuri ◽  
Dipsikha Bhattacharya ◽  
Sumanta Kumar Sahu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Anticancer Drug ◽  
Cell Imaging ◽  
Metal Organic Frameworks ◽  
Mri Contrast Agent ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Anticancer Drug Delivery ◽  
Metal Organic

The development of a novel multifunctional porous nanoplatform for targeted anticancer drug delivery with cell imaging and magnetic resonance imaging has been realised.

TEA-assistant synthesis of MOF-74 nanorods for drug delivery and in-vitro magnetic resonance imaging

2021 ◽  
Vol 315 ◽  
pp. 110900
Author(s):  
Jiaqi Hu ◽  
Yi Chen ◽  
Hui Zhang ◽  
Zhenxia Chen ◽  
Yun Ling ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Resonance Imaging
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