Comparisons between gelatin-tussah silk fibroin/hydroxyapatite and gelatin-Bombyx mori silk fibroin/hydroxyapatite nano-composites for bone tissue engineering

RSC Advances ◽  
2015 ◽  
Vol 5 (93) ◽  
pp. 76526-76537 ◽  
Author(s):  
Jiabing Ran ◽  
Jingxiao Hu ◽  
Guanglin Sun ◽  
Si Chen ◽  
Li Chen ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bombyx Mori ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Nano Composites ◽  
Enhancement Mechanism ◽  
Hydroxyapatite Composite ◽  
Bombyx Mori Silk ◽  
Tussah Silk Fibroin

Enhancement mechanism of tussah silk fibroin to gelatin-tussah silk fibroin/hydroxyapatite composite.

scholarly journals Silk Fibroin-Alginate-Hydroxyapatite Composite Particles in Bone Tissue Engineering Applications In Vivo

2017 ◽  
Vol 18 (4) ◽  
pp. 858 ◽  
Author(s):  
You-Young Jo ◽  
Seong-Gon Kim ◽  
Kwang-Jun Kwon ◽  
HaeYong Kweon ◽  
Weon-Sik Chae ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Composite Particles ◽  
Engineering Applications ◽  
Hydroxyapatite Composite

scholarly journals Oxygen Permeability of Silk Fibroin Hydrogels and Their Use as Materials for Contact Lenses: A Purposeful Analysis

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 58
Author(s):  
Traian V. Chirila
Keyword(s):  
Tissue Engineering ◽  
Bombyx Mori ◽  
Silk Fibroin ◽  
Biomedical Applications ◽  
Oxygen Permeability ◽  
Contact Lenses ◽  
The Past ◽  
Fibrous Protein ◽  
Silk Moth ◽  
Bombyx Mori Silk

Fibroin is a fibrous protein that can be conveniently isolated from the silk cocoons produced by the larvae of Bombyx mori silk moth. In its form as a hydrogel, Bombyx mori silk fibroin (BMSF) has been employed in a variety of biomedical applications. When used as substrates for biomaterial-cells constructs in tissue engineering, the oxygen transport characteristics of the BMSF membranes have proved so far to be adequate. However, over the past three decades the BMSF hydrogels have been proposed episodically as materials for the manufacture of contact lenses, an application that depends on substantially elevated oxygen permeability. This review will show that the literature published on the oxygen permeability of BMSF is both limited and controversial. Additionally, there is no evidence that contact lenses made from BMSF have ever reached commercialization. The existing literature is discussed critically, leading to the conclusion that BMSF hydrogels are unsuitable as materials for contact lenses, while also attempting to explain the scarcity of data regarding the oxygen permeability of BMSF. To the author’s knowledge, this review covers all publications related to the topic.

Development of silk fibroin/nanohydroxyapatite composite hydrogels for bone tissue engineering

2015 ◽  
Vol 67 ◽  
pp. 66-77 ◽  
Author(s):  
Marta Ribeiro ◽  
Mariana A. de Moraes ◽  
Marisa M. Beppu ◽  
Mónica P. Garcia ◽  
Maria H. Fernandes ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Composite Hydrogels

Chitosan/β-TCP composites scaffolds coated with silk fibroin: a bone tissue engineering approach

2021 ◽  
Vol 17 (1) ◽  
pp. 015003
Author(s):  
Lya Piaia ◽  
Simone S Silva ◽  
Joana M Gomes ◽  
Albina R Franco ◽  
Emanuel M Fernandes ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Cellular Proliferation ◽  
Mechanical Performance ◽  
Tissue Growth ◽  
Polymeric Scaffolds ◽  
Bioactive Agents

Abstract Bone regeneration and natural repair are long-standing processes that can lead to uneven new tissue growth. By introducing scaffolds that can be autografts and/or allografts, tissue engineering provides new approaches to manage the major burdens involved in this process. Polymeric scaffolds allow the incorporation of bioactive agents that improve their biological and mechanical performance, making them suitable materials for bone regeneration solutions. The present work aimed to create chitosan/beta-tricalcium phosphate-based scaffolds coated with silk fibroin and evaluate their potential for bone tissue engineering. Results showed that the obtained scaffolds have porosities up to 86%, interconnectivity up to 96%, pore sizes in the range of 60–170 μm, and a stiffness ranging from 1 to 2 MPa. Furthermore, when cultured with MC3T3 cells, the scaffolds were able to form apatite crystals after 21 d; and they were able to support cell growth and proliferation up to 14 d of culture. Besides, cellular proliferation was higher on the scaffolds coated with silk. These outcomes further demonstrate that the developed structures are suitable candidates to enhance bone tissue engineering.

Silk Fibroin-Based Scaffold for Bone Tissue Engineering

2018 ◽  
pp. 371-387 ◽  
Author(s):  
Joo Hee Choi ◽  
Do Kyung Kim ◽  
Jeong Eun Song ◽  
Joaquim Miguel Oliveira ◽  
Rui Luis Reis ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Silk Fibroin
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