An environmentally friendly preparation and characterization of waterborne polyurethane hydrogels by polyvinyl alcohol physical cross-linking to improve water absorption

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73882-73891 ◽  
Author(s):  
Cai Wang ◽  
Yudong Zheng ◽  
Kun Qiao ◽  
Yajie Xie ◽  
Xiaoteng Zhou

The PU/PVA hydrogels had three stages of water absorption. The quick absorption kinetics and high equilibrium water absorption of 70% PU/PVA as​ wound dressing material could absorb excess exudate and create a moist wound healing environment.

e-Polymers ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Ying Wu ◽  
Qing Yang ◽  
Yali Gi ◽  
Yueting Zhang

AbstractA novel hydrogel wound dressing with semi-interpenetrating polymer network structure (semi-IPN) was prepared by radical polymerization of acrylic acid with potassium persulfate (K2S2O8) as initiator and N, N'-methylenebisacrylamide (MBA) as cross-linking agent in the presence of chitosan (CTS) and polyvinyl pyrrolidone (PVP). Hydrogels were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). SEM displayed semi- IPN hydrogels' creased surface with some scale-like wrinkles, thus improving the absorptive capability which has been considered as a most important characteristic of wound dressings. It was found that the content of cross-linking agent and the mass ratio of PVP and CTS had much influence on the mechanical properties of the hydrogel, varying from brittle plastics to elastomer due to the different degrees of cross linking. Since tensile strength is partly in inverse ratio to the hydrogel absorbent capability, the article offers an analysis of varying material proportion in order to obtain an optimum properties of the hydrogel wound dressing .


2016 ◽  
Vol 4 (11) ◽  
pp. 1682-1690 ◽  
Author(s):  
Hongye Hao ◽  
Jingyu Shao ◽  
Ya Deng ◽  
Shan He ◽  
Feng Luo ◽  
...  

Light-crosslinking waterborne polyurethanes (LWPUs) based on lysine possess appropriate elasticity for soft tissue repair, and can induce macrophages into a wound healing phenotype.


2015 ◽  
Vol 3 (7) ◽  
pp. 1415-1425 ◽  
Author(s):  
N. Duraipandy ◽  
Rachita Lakra ◽  
Kunnavakkam Vinjimur Srivatsan ◽  
Usha Ramamoorthy ◽  
Purna Sai Korrapati ◽  
...  

Wound dressing material based on nano-biotechnological intervention by caging plumbagin on silver nanoparticle (PCSN) as a multi-site cross-linking agent of collagen scaffolds with potent anti-microbial and wound healing activity.


2007 ◽  
Vol 342-343 ◽  
pp. 69-72 ◽  
Author(s):  
Min Suk Lee ◽  
In Bum Song ◽  
Gil Son Khang ◽  
Moon Suk Kim ◽  
Hai Bang Lee

To develop a wound dressing that can be removed from the injured skin without the damage and supporting rapid healing, we made hybrid dressing of small intestinal submucosa (SIS) and hydrogels. Alginate and gelatin used as a dressing material in hydrogels were selected to coat SIS sheets. Characteristics and tendency of wound healing of prepared sheets were investigated. Water uptake ability was greater when the sheets were coated with gelatin than alginate although both showed higher water absorption than the native SIS sheets, but the degradation rate of alginate/gelatin coated SIS was slower than that of native SIS because both polymers may delay contact time of enzyme to the SIS surface in solution. It was observed that less of fibroblasts attached to the natural polymer coated SIS sheets. This property will make easy for the detachment of the sheet from the defected tissue. Wound closure examination showed that prepared sheets enhanced wound healing. It was concluded that prepared alginate/gelatin coated SIS sheets are positively regarded as an appropriate biodegradable wound dressing that is reducing patient’s pain during change of the dressing.


2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Erika Adomavičiūtė ◽  
Sigitas Stanys ◽  
Modestas Žilius ◽  
Vaida Juškaitė ◽  
Alvydas Pavilonis ◽  
...  

Antibacterial, antiviral, antifungal, antioxidant, anti-inflammatory, and anticancer activities of propolis and its ability to stimulate the immune system and promote wound healing make it a proper component for wound dressing materials. Silver nanoparticles are recognized to demonstrate strong antiseptic and antimicrobial activity; thus, it also could be considered in the development of products for wound healing. Combining propolis and silver nanoparticles can result in improved characteristics of products designed for wound healing and care. The aim of this study was to formulate electrospun fast dissolving mats for wound dressing containing propolis ethanolic extract and silver nanoparticles. Produced electrospun nano/microfiber mats were evaluated studying their structure, dissolution rate, release of propolis phenolic compounds and silver nanoparticles, and antimicrobial activity. Biopharmaceutical characterization of electrospun mats demonstrated fast release of propolis phenolic compounds and silver nanoparticles. Evaluation of antimicrobial activity onStaphylococcus aureus,Staphylococcus epidermidis,Enterococcus faecalis,Escherichia coli,Pseudomonas aeruginosa,Proteus vulgaris,Bacillus subtilis,Bacillus cereus, andCandida albicansstrains confirmed the ability of electrospun mats to inhibit the growth of the tested microorganisms.


2011 ◽  
Vol 287-290 ◽  
pp. 2721-2724 ◽  
Author(s):  
Ching Wen Lou ◽  
Jin Jia Hu ◽  
Chao Chiung Huang ◽  
Chao Tsang Lu ◽  
Cheng Tien Hsieh ◽  
...  

In this study, the polyester fiber (PET) and absorbent cotton (AC) blend was needle-bonded to make the nonwoven PET/AC composite wound dressing matrix fabrics. The combined advantages of mechanical strength due to PET and water absorption due to AC make the composite nonwoven an attracting wound dressing matrix fabric. We examined physical features, such as mechanical properties, air permeability, softness, water imbibition, and water absorption rate, of the nonwovens made of different blending ratios of PET and AC. We found that while the strength and air permeability were slightly reduced at blending ratio of 80:20, the water imbibition increased about 1.6 cm for the same nonwoven. The results suggested that the optimal blending ratio for the nonwoven to be used as a wound dressing matrix is 80:20.


2017 ◽  
Vol 898 ◽  
pp. 2095-2100 ◽  
Author(s):  
Zhi Hua Lu ◽  
Dong Mei Zhao ◽  
Cheng Shun Li

A novel silk fibroin (SF) based bi-layered wound dressing was successfully developed by spraying chitosan (CS) solution on the ring spun silk fibroin fabric. SEM micrographs showed that chitosan solution formed a thin film on the degummed silk fibroin fabric, which had a connective porous structure. The antibacterial property, indirect cytotoxicity and the wound healing properties of the materials were investigated. Comparing with the commercial wound dressing, the bi-layered SF/CS wound dressing could accelerate the wound healing, and may be a potential choice for skin regeneration.


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