Graphene oxide wrapped gold nanorods for enhanced photo-thermal stability

RSC Advances ◽  
2015 ◽  
Vol 5 (68) ◽  
pp. 54971-54977 ◽  
Author(s):  
Qingli Wei ◽  
Hong Ni ◽  
Xue Jin ◽  
Jing Yuan
Keyword(s):  
Thermal Stability ◽  
Graphene Oxide ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Nir Laser

NanoGO wrapped Gold nanorods show enhanced photothermal stability under continuous NIR laser irradiation.

scholarly journals Plasmonic photothermal microneedle arrays and single needles for minimally-invasive deep in-skin hyperthermia

2020 ◽  
Vol 8 (25) ◽  
pp. 5425-5433 ◽  
Author(s):  
Álvaro Cárcamo-Martínez ◽  
Brónach Mallon ◽  
Juan Domínguez-Robles ◽  
A. Sara Cordeiro ◽  
Maurizio Celentano ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Skin Model ◽  
Thickness Skin ◽  
Microneedle Arrays ◽  
First Time ◽  
Nir Laser ◽  
Deep Hyperthermia

We report, for the first time, crosslinked polymeric microneedle (MN) arrays and single needles (2 mm and 4.5 mm length) coated with gold nanorods (GnRs) to induce deep hyperthermia in a 3 mm-thickness skin model upon near infrared (NIR) laser irradiation.

scholarly journals Doxorubicin loaded gold nanorods: a multifunctional chemo-photothermal nano-platform for cancer management

2020 ◽  
Author(s):  
Uzma Azeem Awan ◽  
Abida Raza ◽  
Shaukat Ali ◽  
Rida Fatima Saeed ◽  
Nosheen Akhtar
Keyword(s):  
Side Effects ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Drug Loading ◽  
Maximum Efficiency ◽  
High Dose ◽  
Laser Exposure ◽  
Cancer Management ◽  
Cell Inhibition ◽  
Nir Laser

One of the limitations associated with cancer treatment is low efficacy and high dose-related side effects of anticancer drugs. The purpose of the current study was to fabricate biocompatible multifunctional drug loaded nano-moieties for co-therapy (chemo-photothermal therapy) with maximum efficiency and minimum side effects. Herein, we report in vitro anticancerous effects of doxorubicin (DOX) loaded on polyelectrolyte-poly (sodium-4-styrenesulfonate) coated Gold nanorods (PSS-GNRs) with and without NIR laser (808 nm, power density = 1.5 W/cm2 for 2 min) exposure. Drug loading capacity of PSS-GNRs was about 76% with drug loading content of 3.2 mg DOX/mL. Cumulative DOX release significantly increased after laser exposure (1.5 W/cm2) compared to non-irradiated samples (p<0.05). Zeta potential of GNRs, PSS-GNRs and DOX-PSS-GNRs was recorded as +42 ±0.1 mV, – 40 ±0.3 mV and 39.3 ±0.6 mV, respectively. PSS-GNRs nano-complexes were found biocompatible and showed higher photothermal stability. DOX conjugated nano-complexes with NIR laser irradiation appear more efficient in cell inhibition (93%) than without laser exposure (65%) and doxorubicin alone (84%). The IC50 of PSS-GNRs-DOX and PSS-GNRs-DOX was recorded as 7.99 ±0.0032 and 3.12 ±0.0906 µg/mL with laser irradiation. Thus, a combinatorial approach based on chemo and photothermal strategy appears to be a promising platform in cancer management.

scholarly journals Doxorubicin-loaded gold nanorods: a multifunctional chemo-photothermal nanoplatform for cancer management

2021 ◽  
Vol 12 ◽  
pp. 295-303
Author(s):  
Uzma Azeem Awan ◽  
Abida Raza ◽  
Shaukat Ali ◽  
Rida Fatima Saeed ◽  
Nosheen Akhtar
Keyword(s):  
Side Effects ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Drug Loading ◽  
High Dose ◽  
Laser Exposure ◽  
Cancer Management ◽  
Cell Inhibition ◽  
Nir Laser

Two of the limitations associated with cancer treatment are the low efficacy and the high dose-related side effects of anticancer drugs. The purpose of the current study was to fabricate biocompatible multifunctional drug-loaded nanoscale moieties for co-therapy (chemo-photothermal therapy) with maximum efficacy and minimum side effects. Herein, we report in vitro anticancerous effects of doxorubicin (DOX) loaded on gold nanorods coated with the polyelectrolyte poly(sodium-4-styrenesulfonate) (PSS-GNRs) with and without NIR laser (808 nm, power density = 1.5 W/cm2 for 2 min) irradiation. The drug-loading capacity of PSS-GNRs was about 76% with a drug loading content of 3.2 mg DOX/mL. The cumulative DOX release significantly increased after laser exposure compared to non-irradiated samples (p < 0.05). The zeta potential values of GNRs, PSS-GNRs and DOX-PSS-GNRs were measured as 42 ± 0.1 mV, −40 ± 0.3 mV and 39.3 ± 0.6 mV, respectively. PSS-GNRs nanocomplexes were found to be biocompatible and showed higher photothermal stability. The DOX-conjugated nanocomplexes with NIR laser irradiation appear more efficient in cell inhibition (93%) than those without laser exposure (65%) and doxorubicin alone (84%). The IC50 values of PSS-GNRs-DOX and PSS-GNRs-DOX were measured as 7.99 and 3.12 µg/mL, respectively, with laser irradiation. Thus, a combinatorial approach based on chemotherapy and photothermal strategies appears to be a promising platform in cancer management.

scholarly journals Ultra-high thermally stable gold nanorods/radial mesoporous silica and their application in enhanced chemo-photothermal therapy

RSC Advances ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 10416-10424
Author(s):  
Chun Shan ◽  
Yuting Huang ◽  
Junhao Wei ◽  
Min Chen ◽  
Limin Wu
Keyword(s):  
Thermal Stability ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Conversion Efficiency ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
High Thermal Stability ◽  
Loading Capacity ◽  
On Demand ◽  
Nir Laser

AuNRs coated with ultra-thick SiO2 shells exhibited ultra-high thermal stability (800 °C), excellent photothermal conversion efficiency (70%) and outstanding loading capacity. The drug release could be nicely controlled by acidity and NIR laser to achieve the “On-demand” mode.

scholarly journals Thermal-Recoverable Tough Hydrogels Enhanced by Porphyrin Decorated Graphene Oxide

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1487 ◽  
Author(s):  
Wang ◽  
Wei ◽  
Su ◽  
Qiu ◽  
Hu ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Graphene Oxide ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Mechanical Performance ◽  
The Body ◽  
Compressive Property ◽  
Photothermal Method ◽  
Nir Laser

Artificial tissue materials usually suffer properties and structure loss over time. As a usual strategy, a new substitution is required to replace the worn one to maintain the functions. Although several approaches have been developed to restore the mechanical properties of hydrogels, they require direct heating or touching, which cannot be processed within the body. In this manuscript, a photothermal method was developed to restore the mechanical properties of the tough hydrogels by using near infrared (NIR) laser irradiation. By adding the porphyrin decorated graphene oxide (PGO) as the nanoreinforcer and photothermal agent into carrageenan/polyacrylamide double network hydrogels (PDN), the compressive strength of the PDN was greatly improved by 104%. Under a short time of NIR laser irradiation, the PGO effectively converts light energy to thermal energy to heat the PDN hydrogels. The damaged carrageenan network was rebuilt, and a 90% compressive strength recovery was achieved. The PGO not only significantly improves the mechanical performance of PDN, but also restores the compressive property of PDN via a photothermal method. These tough hydrogels with superior photothermal recovery may work as promising substitutes for load-bearing tissues.

Enhanced Thermal Stability and Biocompatibility of Gold Nanorods by Graphene Oxide

Plasmonics ◽  
2017 ◽  
Vol 13 (5) ◽  
pp. 1585-1594 ◽  
Author(s):  
Vahid Shirshahi ◽  
Shadie Hatamie ◽  
Seyed Nasrollah Tabatabaei ◽  
Marzieh Salimi ◽  
Reza Saber
Keyword(s):  
Thermal Stability ◽  
Graphene Oxide ◽  
Gold Nanorods

scholarly journals Extraordinary thermal behavior of graphene oxide in air for electrode applications

2021 ◽  
Author(s):  
Joong Tark Han ◽  
Joon Young Cho ◽  
Jeong Hoon Kim
Keyword(s):  
Thermal Stability ◽  
Graphene Oxide ◽  
Physical Properties ◽  
Thermal Behavior ◽  
Stability Of Solution ◽  
Exfoliated Graphene ◽  
Potential Applications ◽  
Thermal Stability Of

The thermal stability of solution-exfoliated graphene oxide (GO) in air is one of the most important physical properties influencing its potential applications. To date, majority of the GO prepared by...

Optoporation and Recovery of Living Cells under Au Nanoparticle Layer-Mediated NIR-Laser Irradiation

2021 ◽  
Author(s):  
Timofey E. Pylaev ◽  
Yuri Efremov ◽  
Elena S. Avdeeva ◽  
Artem A. Antoshin ◽  
Anastasiia I. Shpichka ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Living Cells ◽  
Au Nanoparticle ◽  
Nanoparticle Layer ◽  
Nir Laser
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