Development of novel small peptide ligands for antibody purification

RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 67093-67101 ◽  
Author(s):  
Yuping Wei ◽  
Jiandong Xu ◽  
Liang Zhang ◽  
Yankai Fu ◽  
Xia Xu
Keyword(s):  
Immunoglobulin G ◽  
Molecular Simulations ◽  
Peptide Ligands ◽  
Human Immunoglobulin ◽  
Small Peptide ◽  
Antibody Purification ◽  
Human Immunoglobulin G ◽  
Elution Condition ◽  
Potential Alternative

Small peptide ligands which were designed based on the interactions with human immunoglobulin G (IgG) using the molecular simulations, can offer a potential alternative for mAb purification with elution condition at pH 9 and pH 3.

Cleavage of Human Immunoglobulin G by Treponema denticola

Anaerobe ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Daniel Grenier ◽  
Denis Mayrand
Keyword(s):  
Immunoglobulin G ◽  
Human Immunoglobulin ◽  
Treponema Denticola ◽  
Human Immunoglobulin G

Fractionation of human immunoglobulin G by chromatography on Remazol Yellow GGL-Sepharose

1982 ◽  
Vol 10 (2) ◽  
pp. 104-104 ◽  
Author(s):  
PETER G. H. BYFIELD ◽  
SUE COPPING ◽  
WILLIAM A. BARTLETT
Keyword(s):  
Immunoglobulin G ◽  
Human Immunoglobulin ◽  
Human Immunoglobulin G

Heat-polymerization of human immunoglobulin G

1973 ◽  
Vol 10 (9) ◽  
pp. 583-589
Author(s):  
Ryuichi Yokohari ◽  
Koyo Takeda ◽  
Yukio Imamura
Keyword(s):  
Immunoglobulin G ◽  
Human Immunoglobulin ◽  
Human Immunoglobulin G ◽  
Heat Polymerization

Suppression of liver uptake of orally fed liposomes by injection (I.P.) of dextran sulfate 500

1987 ◽  
Vol 7 (6) ◽  
pp. 465-470 ◽  
Author(s):  
Nirmalendu Das ◽  
Mukul Kumar Basu ◽  
Manoj Kumar Das
Keyword(s):  
Gastrointestinal Tract ◽  
Immunoglobulin G ◽  
Dextran Sulfate ◽  
Portal Blood ◽  
Human Immunoglobulin ◽  
Liver Uptake ◽  
Human Immunoglobulin G

125Iodine labelled human immunoglobulin-G encapsulated liposomes were administered orally to rats. Distribution of radioactivity was checked in various tissues and in portal blood. The effect of dextran sulfate (DS 500,000 m. wt., liver blockade agent) injection (i.p.) on the liver uptake of liposomes and on the amount of liposomes appearing in the portal blood from the gastrointestinal tract have been studied. An increased amount of radioactivity was observed in the portal blood and the amount of radioactivity in the liver decreased appreciably after injection of dextran sulfate. In both the cases the action of dextran sulfate started 2 hours after injection and reached maximum at 12 hour, falling slightly at 24 hour.

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