Catalytic system for pyridine oxidation to N-oxides under mild conditions based on polyoxomolybdate

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36809-36812 ◽  
Author(s):  
Chunxia Yang ◽  
Wei Zhao ◽  
Zhiguo Cheng ◽  
Baomin Luo ◽  
Dongqin Bi
Keyword(s):  
Catalytic System ◽  
Room Temperature ◽  
Mild Conditions ◽  
High Yields

A reusable and effective catalytic system has been developed for oxidation of pyridines catalyzed by Keplerate polyoxomolybdate ({Mo132}) at room temperature. Pyridine compounds could be oxidized in high yields under mild conditions.

Direct catalytic synthesis of densely substituted 3-formylpyrroles from imines and 1,4-ketoaldehydes

RSC Advances ◽  
2014 ◽  
Vol 4 (65) ◽  
pp. 34548-34551 ◽  
Author(s):  
Indresh Kumar ◽  
Nisar A. Mir ◽  
Panduga Ramaraju ◽  
Deepika Singh ◽  
Vivek K. Gupta ◽  
...  
Keyword(s):  
Room Temperature ◽  
Catalytic Synthesis ◽  
Mild Conditions ◽  
High Yields

An organocatalytic formal [3 + 2] cycloaddition have been developed between 1,4-ketoaldehydes and imines to synthesize densely substituted 3-formylpyrroles in high yields (up to 70%) under mild conditions at room temperature.

[bmim]PF6/KOH: A Recyclable Catalytic System for an Azide–Arylacetaldehyde [3 + 2] Cycloaddition

2017 ◽  
Vol 41 (11) ◽  
pp. 631-635
Author(s):  
Yuqin Jiang ◽  
Kai Wu ◽  
Xuxia Tan ◽  
Dandan Zhang ◽  
Wenpei Dong ◽  
...  
Keyword(s):  
Transition Metal ◽  
Organic Solvent ◽  
Catalytic System ◽  
Room Temperature ◽  
Reaction Medium ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Green Protocol ◽  
Mild Conditions

A fast and green protocol for the synthesis of 1,4-disubstituted 1,2,3-triazoles from azides and arylacetaldehydes at room temperature was developed using [bmim]PF6/KOH as the reaction medium. It was found that the in situ-generated carbene from [bmim]PF6/KOH acted as the catalyst. In the absence of a transition-metal catalyst and organic solvent, this azide–arylacetaldehyde [3 + 2] cycloaddition proceeds efficiently, with high levels of regioselectivity, broad range of substrates, excellent yields and simple operation under mild conditions.

scholarly journals Cs2CO3/[bmim]Br as an Efficient, Green, and Reusable Catalytic System for the Synthesis of N-Alkyl Derivatives of Phthalimide under Mild Conditions

2008 ◽  
Vol 2008 ◽  
pp. 1-4 ◽  
Author(s):  
Alireza Hasaninejad ◽  
Abdolkarim Zare ◽  
Ahmad Reza Moosavi-Zare ◽  
Fatemeh Khedri ◽  
Rahimeh Rahimi ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Conjugate Addition ◽  
Reaction Conditions ◽  
Mild Conditions ◽  
Alkyl Derivatives ◽  
High Yields ◽  
Derivatives Of

Aza-conjugate addition of phthalimide to α,β-unsaturated esters efficiently achieves in the presence of catalytic amount of Cs2CO3 and ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under mild reaction conditions (70°C) to afford N-alkyl phthalimides in high yields and relatively short reaction times.

scholarly journals An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Diego M. Ruiz ◽  
Juan C. Autino ◽  
Nancy Quaranta ◽  
Patricia G. Vázquez ◽  
Gustavo P. Romanelli
Keyword(s):  
Room Temperature ◽  
Incipient Wetness Impregnation ◽  
Reaction Conditions ◽  
Commercial Alumina ◽  
Mild Conditions ◽  
Quinoxaline Derivatives ◽  
Incipient Wetness ◽  
High Yields ◽  
Catalytic Test

We report a suitable quinoxaline synthesis using molybdophosphovanadates supported on commercial alumina cylinders as catalysts. These catalysts were prepared by incipient wetness impregnation. The catalytic test was performed under different reaction conditions in order to know the performance of the synthesized catalysts. The method shows high yields of quinoxaline derivatives under heterogeneous conditions. Quinoxaline formation was obtained using benzyl,o-phenylenediamine, and toluene as reaction solvent at room temperature. The CuH2PMo11VO40supported on alumina showed higher activity in the tested reaction. Finally, various quinoxalines were prepared under mild conditions and with excellent yields.

Michael Addition of Aryl Thiols to 3-(2,2,2-Trifluoroethylidene)Oxindoles under Catalyst-Free Conditions: The Rapid Synthesis of Sulfur-Containing Oxindole Derivatives

2018 ◽  
Vol 42 (4) ◽  
pp. 210-214
Author(s):  
Bo Chen ◽  
Jiaheng Lei ◽  
Junling Zhao
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Rapid Synthesis ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Catalyst Free ◽  
Wide Range ◽  
High Yields ◽  
The Michael Addition ◽  
Sulfur Containing

A mild and efficient catalyst-free method for the rapid synthesis at room temperature of 3-thiomethylated oxindole derivatives has been achieved via the Michael addition of aryl thiols to ring and 1-substituted 3-(2,2,2-trifluoroethylidene)oxindoles in dichloromethane. The method was applicable to a wide range of thiols and variously substituted 3-(2,2,2-trifluoroethylidene)oxindoles under mild conditions as demonstrated by the synthesis in high yields with good diastereoselectivities of 30 3-thiomethylated oxindoles bearing a trifluoromethyl group.

Cu(II)/vasicine promoted intramolecular C-O formation: synthesis of benzoxazoles in EtOH

2020 ◽  
Vol 17 ◽  
Author(s):  
Minxin Li ◽  
Meiling Li ◽  
Yanling Tang ◽  
Yun Sun ◽  
Lu Qu ◽  
...  
Keyword(s):  
Catalytic System ◽  
Aromatic Compounds ◽  
Bond Formation ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Mild Conditions ◽  
Cross Coupling Reactions ◽  
High Yields

Aim and Objective: Benzoxazoles are valuable bicyclic aromatic compounds, the construction of benzoxazoles via C-O cross-coupling reactions has attracted more and more attention. Materials and Methods: The best condition of C-O bond formation from o-haloanilides was carried out taking Cu(OTf)2 (5 mol%) and vasicine (10 mol%) as the catalyst in EtOH in present of K2CO3 (2 eq.) for 12 h at 90oC. Results: A series of 2-substituted benzoxazoles have been prepared in high yields from 2-bromoanilides and 2-iodioanilides under mild conditions. Conclusion: We have developed an efficient Cu-vasicine catalytic system for intramolecular C-O bond formation. This strategy is applicable to synthesis of a wide variety of 2-substituted benzoxazoles by intramolecular O-arylation of o-haloanilides.

scholarly journals Recyclable and reusable PdCl2(PPh3)2/PEG-400/H2O system for the hydrophenylation of alkynes with sodium tetraphenylborate

2020 ◽  
pp. 174751982093437
Author(s):  
Rong Liu ◽  
Tingli Zhang ◽  
Bin Huang ◽  
Mingzhong Cai
Keyword(s):  
Catalytic Activity ◽  
Petroleum Ether ◽  
Catalytic System ◽  
Room Temperature ◽  
Sodium Tetraphenylborate ◽  
Peg 400 ◽  
Apparent Loss ◽  
Internal Alkynes ◽  
High Yields

A stable and efficient PdCl2(PPh3)2/PEG-400/H2O catalytic system for the hydrophenylation reaction of alkynes has been developed. In the presence of 3 mol% PdCl2(PPh3)2 and 2 equiv. of HOAc, the hydrophenylation of both terminal and internal alkynes with sodium tetraphenylborate proceeded smoothly in a mixture of PEG-400 and water at room temperature or 50 °C to afford a variety of phenyl-substituted alkenes in moderate to high yields. The isolation of the products was easily performed by extraction with petroleum ether, and the PdCl2(PPh3)2/PEG-400/H2O system could be readily recycled and reused six times without apparent loss of catalytic activity.

scholarly journals SbCl3-Catalyzed conversion of ketones and aldehydes into gem-dihydroperoxides (DHPs) with 30% H2O2

2015 ◽  
Vol 11 (5) ◽  
pp. 3547-3553 ◽  
Author(s):  
Davood Azarifar ◽  
Boshra Mahmoudi ◽  
Kaveh Khosravi
Keyword(s):  
Present Method ◽  
Room Temperature ◽  
Reaction Times ◽  
Experimental Procedure ◽  
Mild Conditions ◽  
Efficient Conversion ◽  
High Yields ◽  
Catalyzed Oxidation

A simple and efficient conversion of ketones and aldehydes into corresponding gem-dihydroperoxides (DHPs) has been developed by SbCl3-catalyzed oxidation with 30% H2O2 at room temperature. The reactions proceeded smoothly under mild conditions at room temperature. Simple experimental procedure, use of inexpensive and non-toxic catalyst, high yields and low reaction times are the main merits of the present method.

Novel cyclization and reductive coupling of bicyclic olefins with alkyl propiolates catalyzed by nickel complexes

2002 ◽  
Vol 74 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Dinesh Kumar Rayabarapu ◽  
Chien-Hong Cheng
Keyword(s):  
Nickel Complex ◽  
Room Temperature ◽  
Nickel Complexes ◽  
Coupling Reaction ◽  
Coupling Reactions ◽  
Reductive Coupling ◽  
Mild Conditions ◽  
Reaction Proceeds ◽  
High Yields ◽  
Alkyl Propiolates

In this article, new metal-mediated cyclization and reductive coupling reactions of bicyclic olefins with alkynes are described. Oxabicyclic alkenes undergo cyclization with alkyl propiolates at 80 C catalyzed by nickel complexes to give benzocoumarin derivatives in high yields. The reaction of bicyclic alkenes (oxa- and azacyclic alkenes) with alkyl propiolates at room temperature in the presence of the same nickel complex gave 1,2-dihydro-napthelene derivatives in good-to-excellent yields. This reductive coupling reaction proceeds under very mild conditions in complete regio- and stereoselective fashion. A mechanism to account for the coumarin formation and the reductive coupling is proposed.

scholarly journals Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and of pyrrolo[1,2-a]phenanthrolines under mild conditions

2014 ◽  
Vol 10 ◽  
pp. 692-700 ◽  
Author(s):  
Rupankar Paira ◽  
Tarique Anwar ◽  
Maitreyee Banerjee ◽  
Yogesh P Bharitkar ◽  
Shyamal Mondal ◽  
...  
Keyword(s):  
Catalytic System ◽  
Cycloaddition Reaction ◽  
Regioselective Synthesis ◽  
Azomethine Ylides ◽  
Dipolar Cycloaddition ◽  
General Applicability ◽  
Mild Conditions ◽  
Stabilized Azomethine Ylides ◽  
High Yields

A new series of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and pyrrolo[1,2-a]phenanthrolines were efficiently built up from an 8-hydroxyquinoline derivative or phenanthroline via 1,3-dipolar cycloaddition reaction involving non-stabilized azomethine ylides, generated in situ from the parent furo[3,2-h]quinoliniums/phenanthroliums, in presence of a copper(II) chloride–phenanthroline catalytic system. The methodology combines general applicability with high yields.

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