Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors

Ahmed Kamal; Md. Ashraf; Shaik Thokhir Basha; S. M. Ali Hussaini; Shamshair Singh; M. V. P. S. Vishnuvardhan; Boppana Kiran; Balasubramanian Sridhar

doi:10.1039/c5ob02022k

Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors

Organic & Biomolecular Chemistry ◽

10.1039/c5ob02022k ◽

2016 ◽

Vol 14 (4) ◽

pp. 1382-1394 ◽

Cited By ~ 11

Author(s):

Ahmed Kamal ◽

Md. Ashraf ◽

Shaik Thokhir Basha ◽

S. M. Ali Hussaini ◽

Shamshair Singh ◽

...

Keyword(s):

Antiproliferative Activity ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Amine Conjugates

A new class of (E)-N-phenyl-3-styrylpyridin-2-amine conjugates were designed and synthesized on the basis of E7010 and resveratrol scaffolds.

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Design, synthesis and biological evaluation of 2-phenylquinoline-4-carboxamide derivatives as a new class of tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.09.004 ◽

2017 ◽

Vol 25 (21) ◽

pp. 5939-5951 ◽

Cited By ~ 6

Author(s):

Li Zhu ◽

Kaixiu Luo ◽

Ke Li ◽

Yi Jin ◽

Jun Lin

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of (E)-3-(3,4-dihydroxyphenyl)acrylylpiperazine derivatives as a new class of tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.05.029 ◽

2014 ◽

Vol 22 (15) ◽

pp. 4285-4292 ◽

Cited By ~ 9

Author(s):

Yong Yin ◽

Fang Qiao ◽

Lu-Yi Jiang ◽

She-Feng Wang ◽

Shao Sha ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.02.002 ◽

2013 ◽

Vol 21 (21) ◽

pp. 6844-6854 ◽

Cited By ~ 38

Author(s):

Guangcheng Wang ◽

Fei Peng ◽

Dong Cao ◽

Zhuang Yang ◽

Xiaolei Han ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

New Class ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms160510173 ◽

2015 ◽

Vol 16 (12) ◽

pp. 10173-10184 ◽

Cited By ~ 1

Author(s):

Ling Zhang ◽

Yunlong Song ◽

Jingjing Huang ◽

Jia Liu ◽

Wenwen Zhu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Novel Acridine and Quinoline Derivatives as Tubulin Polymerization Inhibitors with Anticancer Activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116376 ◽

2021 ◽

pp. 116376

Author(s):

Yichang Ren ◽

Yong Ruan ◽

Binbin Cheng ◽

Ling Li ◽

Jin Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Quinoline Derivatives ◽

Anticancer Activities ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.053 ◽

2019 ◽

Vol 168 ◽

pp. 426-435 ◽

Cited By ~ 14

Author(s):

Min'an Zhai ◽

Shiyuan Liu ◽

Meiqi Gao ◽

Long Wang ◽

Jun Sun ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Design, Synthesis, and Antiproliferative Activity of Some New Pyrazole-Fused Amino Derivatives of the Pyranoxanthenone, Pyranothioxanthenone, and Pyranoacridone Ring Systems: A New Class of Cytotoxic Agents.

ChemInform ◽

10.1002/chin.200238213 ◽

2010 ◽

Vol 33 (38) ◽

pp. no-no

Author(s):

Ioannis K. Kostakis ◽

Prokopios Magiatis ◽

Nicole Pouli ◽

Panagiotis Marakos ◽

Alexios-Leandros Skaltsounis ◽

...

Keyword(s):

Antiproliferative Activity ◽

Cytotoxic Agents ◽

Design Synthesis ◽

Ring Systems ◽

New Class ◽

Amino Derivatives ◽

Derivatives Of

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Design, Synthesis and Evaluation of 2,4‐Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors

ChemMedChem ◽

10.1002/cmdc.202000185 ◽

2020 ◽

Vol 15 (19) ◽

pp. 1802-1812

Author(s):

Frida S. Herrera‐Vázquez ◽

Félix Matadamas‐Martínez ◽

Rodrigo Aguayo‐Ortiz ◽

Laura Dominguez ◽

Teresa Ramírez‐Apan ◽

...

Keyword(s):

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors

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Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111577 ◽

2019 ◽

Vol 181 ◽

pp. 111577 ◽

Cited By ~ 8

Author(s):

Romeo Romagnoli ◽

Paola Oliva ◽

Maria Kimatrai Salvador ◽

Maria Encarnacion Camacho ◽

Chiara Padroni ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112448 ◽

2020 ◽

Vol 200 ◽

pp. 112448 ◽

Cited By ~ 2

Author(s):

Paola Oliva ◽

Romeo Romagnoli ◽

Stefano Manfredini ◽

Andrea Brancale ◽

Salvatore Ferla ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Furan Derivatives ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors

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