Preparation of fluorescent mesoporous hollow silica–fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy

Nanoscale ◽  
2015 ◽  
Vol 7 (28) ◽  
pp. 11894-11898 ◽  
Author(s):  
Yannan Yang ◽  
Meihua Yu ◽  
Hao Song ◽  
Yue Wang ◽  
Chengzhong Yu
Keyword(s):  
Photodynamic Therapy ◽  
Selective Etching ◽  
Particle Sizes ◽  
Combined Chemotherapy ◽  
Excellent Performance ◽  
Hollow Silica ◽  
Fullerene Nanoparticles

Fluorescent mesoporous hollow silica–fullerene nanoparticles with particle sizes of ∼50 nm have been successfully prepared, showing excellent performance in combined chemo-photodynamic therapy.

scholarly journals Folic acid functionalized hollow nanoparticles for selective photodynamic therapy of cutaneous squamous cell carcinoma

2019 ◽  
Vol 3 (6) ◽  
pp. 1113-1122 ◽  
Author(s):  
Duncan Hieu M. Dam ◽  
Lingzhi Zhao ◽  
Sophia A. Jelsma ◽  
Yanli Zhao ◽  
Amy S. Paller
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Folic Acid ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Zinc Phthalocyanine ◽  
Hollow Nanoparticles ◽  
Hollow Silica

Folic acid conjugated hollow silica nanocarriers loaded with zinc phthalocyanine are employed for selective photodynamic therapy of cutaneous squamous cell carcinoma.

scholarly journals Photodynamic Therapy of Human Hepatoma by Photosan-Ii Loaded Hollow Silica Nanoparticles

2014 ◽  
Vol 25 ◽  
pp. v45
Author(s):  
Dongni Pei ◽  
Li Xiong ◽  
Liangwu Lin ◽  
Xiongying Miao ◽  
Xiaofeng Deng ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Silica Nanoparticles ◽  
Human Hepatoma ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles

COFs-confined catalysts: From nanoparticle and nanocluster to single atoms

2021 ◽  
Author(s):  
MengYi Xu ◽  
Cui Lai ◽  
Xigui Liu ◽  
Bisheng Li ◽  
Mingming Zhang ◽  
...  
Keyword(s):  
Catalytic Reaction ◽  
Electronic Structures ◽  
Particle Sizes ◽  
Heterogeneous Catalytic Reaction ◽  
Excellent Performance ◽  
Geometric Shapes ◽  
Heterogeneous Catalytic ◽  
Single Atoms ◽  
Nano Scale

Abstract: In the heterogeneous catalytic reaction, nano-scale particles (nanoparticle, nanocluster, and single atoms) display excellent performance due to its different electronic structures, particle sizes, and geometric shapes. However, nano-scale particles...

Poly(amidoamine) dendrimer-grafted porous hollow silica nanoparticles for enhanced intracellular photodynamic therapy

2013 ◽  
Vol 9 (5) ◽  
pp. 6431-6438 ◽  
Author(s):  
Xia Tao ◽  
Yun-Jie Yang ◽  
Song Liu ◽  
Yan-Zhen Zheng ◽  
Jing Fu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles

Preparation, Characterization and Phototoxicity of Photosan-Loaded Hollow Silica Nanospheres for Photodynamic Therapy

2012 ◽  
Vol 622-623 ◽  
pp. 930-938
Author(s):  
Xiao Feng Deng ◽  
Yu Wen ◽  
Liang Wu Lin ◽  
Li Xiong ◽  
Xiong Ying Miao
Keyword(s):  
Photodynamic Therapy ◽  
Culture Medium ◽  
Red Light ◽  
Light Dose ◽  
Silica Nanospheres ◽  
Hollow Silica ◽  
One Step ◽  
Wet Chemical ◽  
Hollow Silica Nanospheres ◽  
Phosphate Buffered Saline

In this study, Photosan (PS) was loaded onto hollow silica nanospheres using one-step wet chemical-based synthetic route method. Polydispersive index of the Photosan-loaded hollow Silica Nanospheres (PS-loaded NSs) is 0.121±0.01. The photobiological activity of the PS-loaded NSs was evaluated on human cholangiocarcinoma QBC939 cells. Cells were incubated with free PS or PS-loaded NSs for 2 h and then washed with phosphate-buffered saline. Culture medium was added to the wells containing the cells. Finally, the cells were exposed to red light (630 nm) with a light dose of 10J/cm2. The cellular viability was determined after 24 h of incubation. PS-loaded NSs and free PS eliminated about 96.4%±2.0% and 54.7%±1.9% of QBC939 cells, respectively. The phototoxicity was time dependent up to 2 h and concentration dependent at 1-7.5 mg/l. The cells viability decreased with the increase of the light dose in the range of 5-15 J/cm2. In conclusion, PS-loaded NSs are the release systems that promise photodynamic therapy use.

Combined chemotherapy and ALA-based photodynamic therapy in leukemic murine cells

2012 ◽  
Vol 36 (9) ◽  
pp. 1179-1184 ◽  
Author(s):  
Berenice Diez ◽  
Glenda Ernst ◽  
María Julieta Teijo ◽  
Alcira Batlle ◽  
Silvia Hajos ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Combined Chemotherapy
Sign in / Sign up

Export Citation Format

Share Document