Self-assembly and characterization of transferrin–gold nanoconstructs and their interaction with bio-interfaces

Nanoscale ◽  
2015 ◽  
Vol 7 (17) ◽  
pp. 8062-8070 ◽  
Author(s):  
Birgitte H. McDonagh ◽  
Sondre Volden ◽  
Sina M. Lystvet ◽  
Gurvinder Singh ◽  
Marit-Helen G. Ese ◽  
...  

Transferrin (Tf) conjugated to gold nanoparticles and clusters combine the protein's site-specific receptor targeting capabilities with the optical properties imparted by the nano-sized gold.

2011 ◽  
Vol 13 (9) ◽  
pp. 3923-3928 ◽  
Author(s):  
Dong-Feng Zhang ◽  
Qian Zhang ◽  
Li-Ya Niu ◽  
Li Jiang ◽  
Peng-Gang Yin ◽  
...  

2019 ◽  
Vol 294 ◽  
pp. 3-10
Author(s):  
E.A. Dawi ◽  
A. Abdelkader

In this paper, the deposition and optical properties of charge-stabilized gold nanoparticles on silicon oxide substrates is studied, which have been derivatised with (aminopropyl) triemethoxysilane. Monodispersed charged-stabilized colloidal gold nanoparticles with diameters between 20-150 nm were prepared and their self-assembly and optical properties on silica substrates is studied. Atomic force microscopy (AFM) is employed to investigate the nanoparticle monolayers ex situ. Analysis of AFM images provide evidence that the formation of the colloidal nanoparticle monolayers is governed by random sequential adsorption. The results indicate that the ionic strength of the suspension influences the spatial distribution of the nanoparticles. For all sizes of the Au nanoparticles tested, optical simulations of extinction coefficients made by finite-difference time domain (FDTD) indicate a resonance peak in the range of 510-600 nm wavelength of the visible range of the electromagnetic spectrum. The results indicate a simple and inexpensive approach of assembly of plasmonic nanostructures that can find applications in metamaterials and light waveguides.


2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Wan-Joong Kim ◽  
JaeTae Seo ◽  
Chil Seong Ah ◽  
Jasmine Austin ◽  
Shanghee Kim ◽  
...  

Gold nanoparticles exhibited strong surface plasmon absorption and couplings between neighboring particles within bioactivated self-assembly modified their optical properties. Colorimetric analysis on the optical modification of surface plasmon resoanance (SPR) shift and flocculation parameter functionalized bioinspired gold assembly for biophotonic application. The physical origin of bioinspired gold aggregation-induced shifting, decreasing, or broadening of the plasmon absorption spectra could be explained in terms of dynamic depolarization, collisional damping, and shadowing effects.


RSC Advances ◽  
2015 ◽  
Vol 5 (52) ◽  
pp. 42081-42087 ◽  
Author(s):  
Ramesh Raliya ◽  
Pratim Biswas

The synthesis and characterization of stable gold nanoparticles (Au NPs) from gold chloride in soluble protein extracts of tomato (Solanum lycopersicum L.) leaves is demonstrated.


RSC Advances ◽  
2015 ◽  
Vol 5 (122) ◽  
pp. 101101-101109 ◽  
Author(s):  
Birgitte H. McDonagh ◽  
Gurvinder Singh ◽  
Sulalit Bandyopadhyay ◽  
Sina M. Lystvet ◽  
Joseph A. Ryan ◽  
...  

While the size-dependent optical properties of BSA-stabilized gold nanoclusters are well known, the time-dependent growth mechanism remains to be described.


2018 ◽  
Author(s):  
Tao Zhang ◽  
Ingemar André

AbstractRecent advances in protein engineering have enabled methods to control the self-assembly of protein on various length-scales. One attractive application for designed proteins is to direct the spatial arrangement of nanomaterials of interest. Until now, however, a reliable conjugation method is missing to facilitate site-specific positioning. In particular, bare inorganic nanoparticles tend to aggregate in the presence of buffer conditions that are often required for the formation of stable proteins. Here, we demonstrated a DNA mediated conjugation method to link gold nanoparticles with protein structures. To achieve this, we constructed de novo designed protein fibers based on previously published uniform alpha-helical units. DNA modification rendered gold nanoparticles with increased stability against ionic solutions and the use of complementary strands hybridization guaranteed the site-specific binding to the protein. The combination of high resolution placement of anchor points in designed protein assemblies with the increased control of covalent attachment through DNA binding can enable investigations of multilevel physical coupling events of nanocomponents on protein templates and expand the application of protein structures to material sciences.


2015 ◽  
Vol 135 (11) ◽  
pp. 474-475
Author(s):  
Koji Sugano ◽  
Ryoji Hiraoka ◽  
Toshiyuki Tsuchiya ◽  
Osamu Tabata

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