An ultrasensitive sandwich-type electrochemical immunosensor based on δ-MnO2 and palladium nanoparticles covered natural halloysite nanotubes for the detection of hepatitis B surface antigen

2016 ◽  
Vol 40 (1) ◽  
pp. 558-563 ◽  
Author(s):  
Yueyuan Li ◽  
Lihui Tian ◽  
Li Liu ◽  
Lei Liu ◽  
Jingjing Li ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Palladium Nanoparticles ◽  
Hepatitis B Surface Antigen ◽  
Halloysite Nanotubes ◽  
Electrochemical Immunosensor ◽  
Halloysite Nanotube ◽  
Sandwich Type

An ultrasensitive sandwich-type immunosensor for the detection of HBsAg based on the multifunctional natural halloysite nanotube nanocomposites (Pd/δ-MnO2/HNTs).

An Electrochemical Immunosensor with Graphene-Oxide-Ferrocene-based Nanocomposites for Hepatitis B Surface Antigen Detection

2018 ◽  
Vol 30 (11) ◽  
pp. 2774-2780 ◽  
Author(s):  
Feijun Zhao ◽  
Yan Bai ◽  
Ruosheng Zeng ◽  
Liangli Cao ◽  
Jianming Zhu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Electrochemical Immunosensor ◽  
Antigen Detection

An electrochemical immunosensor for ultrasensitive detection of HBsAg based on platinum nanoparticles loaded on natural montmorillonite

2015 ◽  
Vol 7 (21) ◽  
pp. 9150-9157 ◽  
Author(s):  
Yueyuan Li ◽  
Lihui Tian ◽  
Hongying Jia ◽  
Xuehui Pang ◽  
Wei Cao ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Platinum Nanoparticles ◽  
Hepatitis B Surface Antigen ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Platinum Nanoparticle ◽  
Amino Silane

A sensitive and facile electrochemical immunosensor for ultrasensitive detection of Hepatitis B surface antigen (HBsAg) was designed, which was based on platinum nanoparticle decorated amino silane functionalized montmorillonite (Pt–NH2–MMT).

Sensitive electrogravimetric immunoassay of hepatitis B surface antigen through hyperbranched polymer bridge linked to multiple secondary antibodies

2016 ◽  
Vol 70 (8) ◽  
Author(s):  
Li-Qiu Zhang ◽  
Hong-Xia Shen ◽  
Qiong Cheng ◽  
Li-Chun Liu
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Hyperbranched Polymer ◽  
Quartz Crystal ◽  
Immune Reaction ◽  
Limit Of Detection ◽  
Hepatitis B Surface Antigen ◽  
Sandwich Type ◽  
Detection Response ◽  
Secondary Antibodies

AbstractA method for using a hyperbranched polymer (HBP) as a bridge to link multiple secondary antibodies at HBP branches to amplify the detection response signal on a quartz crystal microbalance (QCM)-based sandwich-type immunosensor is reported. Carboxyl groups were prepared at multiple branches of HBP to make possible chemical binding between HBP and secondary antibodies via the carboxyl–amine reaction. The total mass ovcry antibodies were used to enhance the signal on a QCM chip in comparison with a simple sandwich-type immune reaction. By contrast, the proposed method could cause one antigen to analogously react with multiple secondary antibodies as a result of the branch structure of HBP. The strategy of using HBP as a bridge to link multiple secondary antibodies succeeded in quantitatively detecting the hepatitis B surface antigen (HBsAg). By employing demonstrated HBP bridge-linking, the frequency shift on a QCM chip was approximately 5 times greater than conventional methods without modification at secondary antibodies. The limit of detection of HBsAg was achieved as 2.0 ng mL

A novel label-free electrochemical immunosensor for the detection of hepatitis B surface antigen

2016 ◽  
Vol 8 (40) ◽  
pp. 7380-7386 ◽  
Author(s):  
Lihui Tian ◽  
Li Liu ◽  
Yueyuan Li ◽  
Xue Feng ◽  
Qin Wei ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Hepatitis B ◽  
Reduced Graphene Oxide ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Label Free ◽  
Graphene Oxide Nanosheets ◽  
Reduced Graphene

A novel label-free electrochemical immunosensor based on trimetallic NiAuPt nanoparticles on reduced graphene oxide nanosheets (NiAuPt–NGs) was developed for the quantitative detection of hepatitis B surface antigen (HBsAg).

IL10 Promotorpolymorphismen beeinflussen die Hepatitis B Surface Antigen und die Hepatitis A spezifische Immunantwort

2015 ◽  
Vol 41 (08) ◽  
Author(s):  
E Reuss ◽  
N Evers ◽  
N Dietrich ◽  
J Vollmar ◽  
PM Schneider ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis A ◽  
Hepatitis B Surface Antigen

Effects of Vancomycin on Platelets, Plasma Proteins and Hepatitis B Surface Antigen

1975 ◽  
Vol 34 (01) ◽  
pp. 083-093 ◽  
Author(s):  
Barry S Coller ◽  
W. B Lundberg ◽  
Harvey R Gralnick
Keyword(s):  
Hepatitis B ◽  
Factor Viii ◽  
Surface Antigen ◽  
Plasma Proteins ◽  
Hepatitis B Surface Antigen ◽  
Infusion Site ◽  
Vancomycin Therapy ◽  
Intravenous Injections ◽  
Low Concentrations ◽  
High Doses

SummaryThe antibiotic vancomycin shares many similarities with ristocetin, an agent noted for its effects on platelets and plasma fibrinogen. Vancomycin did not aggregate platelets as ristocetin, but platelets were incorporated into precipitates induced by vancomycin. Fibrinogen and factor VIII were precipitated from plasma at low concentrations of vancomycin. The precipitated fibrinogen remained clottable. Hepatitis B surface antigen was selectively precipitated from serum and could be recovered from the precipitate. Rabbits receiving bolus intravenous injections of high doses of vancomycin developed hypofibrinogenemia and thrombocytopenia within minutes and often went on to die. Studies with 125I-vancomycin revealed little stable binding of the antibiotic to platelets or fibrinogen. A relationship is suggested between the potent protein precipitating effects and phlebitis at the infusion site commonly associated with vancomycin therapy.

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