Dietary nucleotides protect against alcoholic liver injury by attenuating inflammation and regulating gut microbiota in rats

2016 ◽  
Vol 7 (6) ◽  
pp. 2898-2908 ◽  
Author(s):  
Xiaxia Cai ◽  
Lei Bao ◽  
Nan Wang ◽  
Jinwei Ren ◽  
Qihe Chen ◽  
...  
Keyword(s):  
Liver Injury ◽  
Gut Microbiota ◽  
Alcoholic Liver Injury ◽  
Dietary Nucleotides

The present study aims to investigate whether nucleotides ameliorate alcoholic liver injury and explores the possible mechanism.

Crosstalk between gut microbiota and host lipid metabolism in a mouse model of alcoholic liver injury by chronic baijiu or ethanol feeding

2022 ◽  
Author(s):  
Cheng Fang ◽  
Qingwu Zhou ◽  
Qingyang Liu ◽  
Wei Jia ◽  
Yan Xu
Keyword(s):  
Lipid Metabolism ◽  
Liver Injury ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Alcoholic Beverage ◽  
Alcoholic Liver Injury ◽  
Ethanol Feeding

This study demonstrates that compounds in baijiu, a traditional Chinese alcoholic beverage, can attenuate the development of ethanol-induced liver injury by regulating the crosstalk between gut microbiota and host lipid metabolism.

Gut dysbiosis correction contributes to the hepatoprotective effects of Thymus quinquecostatus Celak extract against alcohol through the gut–liver axis

2021 ◽  
Author(s):  
Xin Yan ◽  
Yu Wang ◽  
Xue-Yang Ren ◽  
Xiao-Yun Liu ◽  
Jia-Mu Ma ◽  
...  
Keyword(s):  
Liver Injury ◽  
Gut Microbiota ◽  
Alcoholic Liver Injury ◽  
Gut Dysbiosis ◽  
Hepatoprotective Effects ◽  
Gut Microbiota Dysbiosis

Gut microbiota dysbiosis correction contributes to the hepatoprotective effects of Thymus quinquecostatus Celak extract (TQE) against alcoholic liver injury through gut–liver axis modulation.

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice

2019 ◽  
Vol 10 (9) ◽  
pp. 5566-5573 ◽  
Author(s):  
Jingjing Fan ◽  
Yushan Wang ◽  
Ying You ◽  
Zhiyi Ai ◽  
Weichang Dai ◽  
...  
Keyword(s):  
Liver Injury ◽  
Gut Microbiota ◽  
Intestinal Flora ◽  
Alcoholic Liver Injury ◽  
Fermented Ginseng

Fermented ginseng can alleviate alcoholic liver injury by adjusting the intestinal flora.

scholarly journals The Prebiotic-Like Effects of Coprinus comatus Polysaccharides on Gut Microbiota in Normal Mice and Those with Acute Alcoholic Liver Injury: A Comparative Study

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Weidong Li ◽  
Yongxia Wang ◽  
Min Sun ◽  
Yuting Liang ◽  
Xiaoqing Cai ◽  
...  
Keyword(s):  
Liver Injury ◽  
Gut Microbiota ◽  
Comparative Study ◽  
Relative Abundance ◽  
Alcohol Intake ◽  
Alcoholic Liver Injury ◽  
Alcohol Group ◽  
Coprinus Comatus ◽  
Positive Effects ◽  
Microbiota Structure

This study aims to investigate the prebiotic-like effects of Coprinus comatus polysaccharides (CCP) on gut microbiota. Mice were divided into four groups: normal group (NG), alcohol group (AG), polysaccharides group (PG), and alcohol + polysaccharides group (APG). The gut microbiota structure of feces was analyzed by determining the V3-V4 region sequence in 16S rDNA. The results showed CCP could increase the diversity of gut microbiota. Compared with NG, PG had a significantly higher relative abundance of Firmicutes and Lactobacillaceae and a lower abundance of Rikenellaceae. These changes in gut microbiota result in positive effects on gut due to a series of prebiotic-like effects of CCP. At the same time, CCP could improve some adverse changes in gut microbiota caused by acute alcohol intake, such as the increased proportion of Firmicutes, Bacteroidetes, Muribaculaceae, and Lachnospiraceae and the decreased proportion of Rikenellaceae. In conclusion, the CCP has certain prebiotic effects not only on normal mice but also on mice with acute alcoholic liver injury.

scholarly journals S16 * GUT MICROBIOTA, INTESTINAL BARRIER FUNCTION, ENDOTOXEMIA AND ALCOHOLIC LIVER INJURY

2013 ◽  
Vol 48 (suppl 1) ◽  
pp. i17-i17
Author(s):  
S. Barve ◽  
R. Rao ◽  
K. Chaudhry ◽  
G. Samak ◽  
R. Gangwar ◽  
...  
Keyword(s):  
Liver Injury ◽  
Gut Microbiota ◽  
Barrier Function ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function ◽  
Alcoholic Liver Injury
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