Chronic dosing of a simulated pond ecosystem in indoor aquatic mesocosms: fate and transport of CeO2 nanoparticles

2015 ◽  
Vol 2 (6) ◽  
pp. 653-663 ◽  
Author(s):  
M. Tella ◽  
M. Auffan ◽  
L. Brousset ◽  
E. Morel ◽  
O. Proux ◽  
...  
Keyword(s):  
Point Source ◽  
Cerium Oxide ◽  
Fate And Transport ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Pond Ecosystem ◽  
Aquatic Mesocosms ◽  
Continuous Point ◽  
Pond Ecosystems

Indoor aquatic mesocosms were designed to mimic pond ecosystems contaminated by a continuous point-source discharge of cerium oxide nanoparticles (CeO2-NPs).

scholarly journals Физико-химические свойства и антиоксидантная активность наночастиц оксида церия, стабилизированных мальтодекстрином

2021 ◽  
Vol 63 (12) ◽  
pp. 2020
Author(s):  
С.А. Маслова ◽  
И.Н. Бажукова ◽  
А.В. Мышкина ◽  
Е.О. Бакшеев ◽  
М.О. Пронина ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Surface Structure ◽  
Cerium Oxide ◽  
Hydroxyl Radicals ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Structure And Properties ◽  
Peroxidase Enzymes

The study on physicochemical properties of maltodextrin-coated cerium oxide nanoparticles was carried out. The surface structure and properties of CeO2 nanoparticles were investigated. The ability of CeO2 nanoparticles to perform the functions of catalase and peroxidase enzymes, as well as to inactivate hydroxyl radicals was shown.

scholarly journals Cerium Oxide Nanoparticles: Synthesis and Characterization for Biosafe Applications

2021 ◽  
Vol 1 (3) ◽  
pp. 176-189
Author(s):  
Prathima Prabhu Tumkur ◽  
Nithin Krisshna Gunasekaran ◽  
Babu R. Lamani ◽  
Nicole Nazario Bayon ◽  
Krishnan Prabhakaran ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Cerium Oxide ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Diphenyltetrazolium Bromide ◽  
Scanning Electron

Due to its excellent physicochemical properties, cerium oxide (CeO2) has attracted much attention in recent years. CeO2 nanomaterials (nanoceria) are widely being used, which has resulted in them getting released to the environment, and exposure to humans (mostly via inhalation) is a major concern. In the present study, CeO2 nanoparticles were synthesized by hydroxide-mediated method and were further characterized by Scanning Electron Microscopy (SEM), Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersive X-ray Spectroscopy (EDX), Fourier Transform Infrared Spectroscopy (FTIR), and X-ray Diffraction Spectroscopy (XRD). Human lung epithelial (Beas-2B) cells were used to assess the cytotoxicity and biocompatibility activity of CeO2 nanoparticles. 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) and Live/Dead assays were performed to determine the cytotoxicity and biocompatibility of CeO2 nanoparticles. Generation of reactive oxygen species (ROS) by cerium oxide nanoparticles was assessed by ROS assay. MTT assay and Live/Dead assays showed no significant induction of cell death even at higher concentrations (100 μg per 100 μL) upon exposure to Beas-2B cells. ROS assay revealed that CeO2 nanoparticles did not induce ROS that contribute to the oxidative stress and inflammation leading to various disease conditions. Thus, CeO2 nanoparticles could be used in various applications including biosensors, cancer therapy, catalytic converters, sunscreen, and drug delivery.

scholarly journals Protective Effects of Cerium Oxide Nanoparticles on MC3T3-E1 Osteoblastic Cells Exposed to X-Ray Irradiation

2016 ◽  
Vol 38 (4) ◽  
pp. 1510-1519 ◽  
Author(s):  
Cuifen Wang ◽  
Eric Blough ◽  
Xiaoniu Dai ◽  
Omolola Olajide ◽  
Henry Driscoll ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cerium Oxide ◽  
Molecular Mechanisms ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Protective Effects ◽  
X Rays ◽  
Effective Prevention ◽  
X Ray

Background/Aims: Exposure to ionizing radiation can result in bone damage, including decreased osteocyte number and suppressed osteoblastic activity. However, molecular mechanisms remain to be elucidated, and effective prevention strategies are still limited. This study was to investigate whether cerium oxide nanoparticles (CeO2 NP) can protect MC3T3-E1 osteoblast-like cells from damaging effects of X-ray irradiation, and to study the underpinning mechanism(s). Methods: MC3T3-E1, a osteoblast-like cell line, was exposed to X-ray irradiation and treated with different concentration of CeO2 nanoparticles. The micronucleus frequency was counted under a fluorescence microscope. Cell viability was evaluated using MTT assay. The effects of irradiation and CeO2 nanoparticles on alkaline phosphatase activity and MC3T3-E1 mineralization were further assayed. Results: We found that the ratio of micronuclei to binuclei was dose-dependently increased with X-ray irradiation (from 2 to 6 Gy), but diminished with the increased concentration of CeO2 NP treatment (from 50 to 100 nM). Exposure to X-rays (6 Gy) decreased cell viability, differentiation and the mineralization, but CeO2 NP treatment (100 nM) attenuated the deteriorative effects of irradiation. Both intracellular reactive oxygen species (ROS) production and extracellular H2O2 concentration were increased after X-ray irradiation, but reduced following CeO2 NP treatment. Similar to irradiation, exposure to H2O2 (10 µM) elevated the frequency of micronuclei and diminished cell viability and mineralization, while these changes were ameliorated following CeO2 NP treatment. Conclusions: Taken together, our findings suggest that CeO2 nanoparticles exhibit astonishing protective effects on irradiation-induced osteoradionecrosis in MC3T3-E1 cells, and the protective effects appear to be mediated, at least partially, by reducing oxidative stress.

scholarly journals Recent insights into the impact, fate and transport of cerium oxide nanoparticles in the plant-soil continuum

2021 ◽  
Vol 221 ◽  
pp. 112403
Author(s):  
Ved Prakash ◽  
Jose Peralta-Videa ◽  
Durgesh Kumar Tripathi ◽  
Xingmao Ma ◽  
Shivesh Sharma
Keyword(s):  
Cerium Oxide ◽  
Fate And Transport ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Plant Soil ◽  
The Impact

Polyacrylic Acid Modified Cerium Oxide Nanoparticles: Synthesis and Characterization as a Peroxidase Mimic for Non-Enzymatic H2O2 Sensor

2020 ◽  
Vol 16 (5) ◽  
pp. 816-828
Author(s):  
Gurdeep Rattu ◽  
Nishtha Khansili ◽  
Prayaga M. Krishna
Keyword(s):  
Hydrogen Peroxide ◽  
Cerium Oxide ◽  
Polyacrylic Acid ◽  
Spectroscopic Analysis ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Peroxidase Mimic ◽  
Ft Ir ◽  
H2o2 Sensing ◽  
Fluorescence Spectrometer

Background: Cerium oxide nanoparticles (nanoceria) are efficient free-radical scavengers due to their dual valence state and thus exhibit optical and catalytic properties. Therefore, the main purpose of this work was to understand the peroxidase mimic activity of polymer-stabilized nanoceria for enzyme-less H2O2 sensing by fluorescence spectrometer. Objective: This research revealed the development of fluorescence hydrogen peroxide nanosensor based on the peroxidase-like activity of polyacrylic acid stabilized nanoceria (PAA-CeO2 Nps). Methods: PAA-CeO2 Nps were synthesized by simple cross-linking reaction at a low temperature and characterized by XRD, SEM, Zeta potential, TGA, FT-IR and UV-VIS spectroscopic analysis. H2O2 sensing was performed by a fluorescence spectrometer. Results:: The synthesized polymer nanocomposite was characterized by XRD, SEM, TGA, FT-IR and UV-VIS spectroscopic analysis. The XRD diffraction patterns confirmed the polycrystalline nature and SEM micrograph showed nanoparticles having hexagonal symmetry and crystallite size of 32 nm. The broad peak of Ce–O bond appeared at 508 cm-1. UV-VIS measurements revealed a welldefined absorbance peak around 315 nm and an optical band-gap of 3.17 eV. As synthesized PAACeO2 Nps effectively catalysed the decomposition of hydrogen peroxide (H2O2) into hydroxyl radicals. Then terephthalic acid was oxidized by hydroxyl radical to form a highly fluorescent product. Under optimized conditions, the linear range for determination of hydrogen peroxide was 0.01 - 0.2 mM with a limit of detection (LOD) of 1.2 μM. Conclusion: The proposed method is ideally suited for the sensing of H2O2 at a low cost and this detection system enabled the sensing of analytes (sugars), which can enzymatically generate hydrogen peroxide.

Radiosensitizing Effect of Cerium Oxide Nanoparticles on Human Leukemia Cells

2018 ◽  
Vol 6 (2) ◽  
pp. 111-115 ◽  
Author(s):  
Azadeh Montazeri ◽  
Zohreh Zal ◽  
Arash Ghasemi ◽  
Hooman Yazdannejat ◽  
Hossein Asgarian-Omran ◽  
...  
Keyword(s):  
Cerium Oxide ◽  
Leukemia Cells ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Human Leukemia ◽  
Radiosensitizing Effect ◽  
Human Leukemia Cells

Cerium oxide nanoparticles acts as a novel therapeutic agent for ulcerative colitis through anti-oxidative mechanism

Life Sciences ◽  
2021 ◽  
pp. 119500
Author(s):  
Fereshteh Asgharzadeh ◽  
Alireza Hashemzadeh ◽  
Farzad Rahmani ◽  
Atieh Yaghoubi ◽  
Seyedeh Elnaz Nazari ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Cerium Oxide ◽  
Therapeutic Agent ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Novel Therapeutic
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