scholarly journals Endoplasmic reticulum targeting tumour selective photocytotoxic oxovanadium(iv) complexes having vitamin-B6 and acridinyl moieties

2016 ◽  
Vol 45 (2) ◽  
pp. 783-796 ◽  
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

Vitamin-B6 Schiff base complexes of oxovanadium(iv) having (acridinyl)dipyridophenazine show tumor selective visible light-induced photocytotoxicity by endoplasmic reticulum targeting1O2-mediated apoptosis.

2014 ◽  
Vol 50 (42) ◽  
pp. 5590-5592 ◽  
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Radhika N. Shridharan ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

An oxovanadium(iv) Schiff base vitamin-B6 complex of (acridinyl)dipyridophenazine shows ER-targeted photo-induced anticancer activity while being non-toxic in the dark and to normal cells.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Samik Gupta

Abstract Pyridoxal and Pyridoxal 5-phosphate are two among the six aqua soluble vitamers of vitamin B6. They can form Schiff bases readily due to the presence of aldehyde group. Schiff bases can offer diverse coordination possibilities for many transition metals as has been found in a large volume of research till now. The coordination complexes thus formed gives insight into the active core structure and enzymatic activities of vit B6 containing enzymes. Apart from that, these complexes have been found useful as catalysts for synthesis of fine chemicals, as sensors and for their diverse biological activities.


2015 ◽  
Vol 44 (32) ◽  
pp. 14483-14493 ◽  
Author(s):  
Chuanjun Wang ◽  
Yong Chen ◽  
Wen-Fu Fu

New Pt(ii) and Ru(ii) complexes with Schiff base ligands display effective visible-light catalytic water reduction and Ce4+-driven oxidation activities, respectively.


2019 ◽  
Vol 55 (85) ◽  
pp. 12877-12878
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Radhika N. Shridharan ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

Correction for ‘Endoplasmic reticulum targeted chemotherapeutics: the remarkable photo-cytotoxicity of an oxovanadium(iv) vitamin-B6 complex in visible light’ by Samya Banerjee et al., Chem. Commun., 2014, 50, 5590–5592.


ChemPlusChem ◽  
2015 ◽  
Vol 80 (10) ◽  
pp. 1541-1546 ◽  
Author(s):  
Deepak Prakash Shelar ◽  
Ting-Ting Li ◽  
Yong Chen ◽  
Wen-Fu Fu

2019 ◽  
Vol 48 (42) ◽  
pp. 16124-16125
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

Correction for ‘Endoplasmic reticulum targeting tumour selective photocytotoxic oxovanadium(iv) complexes having vitamin-B6 and acridinyl moieties’ by Samya Banerjee et al., Dalton Trans., 2016, 45, 783–796.


2018 ◽  
Vol 15 (8) ◽  
pp. 3020-3031 ◽  
Author(s):  
Mun Juinn Chow ◽  
Maria V. Babak ◽  
Kwan Wei Tan ◽  
Mei Chi Cheong ◽  
Giorgia Pastorin ◽  
...  

Author(s):  
V.J. Montpetit ◽  
S. Dancea ◽  
L. Tryphonas ◽  
D.F. Clapin

Very large doses of pyridoxine (vitamin B6) are neurotoxic in humans, selectively affecting the peripheral sensory nerves. We have undertaken a study of the morphological and biochemical aspects of pyridoxine neurotoxicity in an animal model system. Early morphological changes in dorsal root ganglia (DRG) associated with pyridoxine megadoses include proliferation of neurofilaments, ribosomes, rough endoplasmic reticulum, and Golgi complexes. We present in this report evidence of the formation of unique aggregates of microtubules and membranes in the proximal processes of DRG which are induced by high levels of pyridoxine.


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