Endoplasmic reticulumtargeted chemotherapeutics: the remarkable photo-cytotoxicity of an oxovanadium(iv) vitamin-B6 complex in visible light

2014 ◽  
Vol 50 (42) ◽  
pp. 5590-5592 ◽  
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Radhika N. Shridharan ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

An oxovanadium(iv) Schiff base vitamin-B6 complex of (acridinyl)dipyridophenazine shows ER-targeted photo-induced anticancer activity while being non-toxic in the dark and to normal cells.

2016 ◽  
Vol 45 (2) ◽  
pp. 783-796 ◽  
Author(s):  
Samya Banerjee ◽  
Akanksha Dixit ◽  
Anjali A. Karande ◽  
Akhil R. Chakravarty

Vitamin-B6 Schiff base complexes of oxovanadium(iv) having (acridinyl)dipyridophenazine show tumor selective visible light-induced photocytotoxicity by endoplasmic reticulum targeting1O2-mediated apoptosis.


2021 ◽  
Vol 157 ◽  
pp. 106329
Author(s):  
Tanlong Xue ◽  
Yang Li ◽  
Xiangchen Zhao ◽  
Jun Nie ◽  
Xiaoqun Zhu

2021 ◽  
Author(s):  
Nazanin Kordestani ◽  
Hadi Amiri Rudbari ◽  
Alexandra R Fernandes ◽  
Luís R Raposo ◽  
André Luz ◽  
...  

To investigate the effect of different halogen substituents, leaving groups and the flexibility of ligand on the anticancer activity of copper complexes, sixteen copper(II) complexes with eight different tridentate Schiff-base...


Nanoscale ◽  
2021 ◽  
Author(s):  
Hu Liu ◽  
Mengqi Shen ◽  
Peng Zhou ◽  
Zhi Guo ◽  
Xinyang Liu ◽  
...  

Developing an efficient single component photocatalyst for overall water splitting under visible-light irradiation is extremely challenging. Herein, we report a metal-free graphitic carbon nitride (g-CxN4)-based nanosheet photocatalyst (x = 3.2,...


2021 ◽  
Vol 505 ◽  
pp. 111528
Author(s):  
Abdollah Neshat ◽  
Mohammad Gholinejad ◽  
Hafize Özcan ◽  
Faezeh Khosravi ◽  
Ali Mousavizadeh Mobarakeh ◽  
...  

INDIAN DRUGS ◽  
2019 ◽  
Vol 56 (03) ◽  
pp. 12-17
Author(s):  
Manpreet Kaur ◽  
S. Singh ◽  

A new series of 2,5-disubstituted-1,3,4-oxadiazole derivatives has been synthesized with the help of different aromatic benzaldehydes and final compounds were characterized by FTIR and 1H NMR. 2,5- disubstituted-1,3,4-oxadiazole derivatives were synthesized by the reaction of Schiff base derivatives with 2,5-disubstituted-1,3,4-oxadiazoles. All the synthesized compounds were screened for their anticancer activity. These compounds were evaluated for their anticancer activity against various cancer cell lines. Five of the compounds possessed good to moderate anti-cancer activity. Three of the synthesized compounds i.e. 6a, 6f and 6g were found to possess maximum growth inhibition. The order for the % control growth inhibition of MCF-7 was found to be 6a>6f>6g>5b>6h, as shown in Table II-VI.


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