scholarly journals Design considerations for the synthesis of polymer coated iron oxide nanoparticles for stem cell labelling and tracking using MRI

2015 ◽  
Vol 44 (19) ◽  
pp. 6733-6748 ◽  
Author(s):  
Michael Barrow ◽  
Arthur Taylor ◽  
Patricia Murray ◽  
Matthew J. Rosseinsky ◽  
Dave J. Adams
Keyword(s):  
Stem Cell ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cell Tracking ◽  
Polymer Coatings ◽  
Mri Contrast Agents ◽  
Cell Labelling ◽  
Oxide Nanoparticles ◽  
Mri Contrast ◽  
Design Considerations

This tutorial review provides an introduction to the design, polymer selection and synthesis strategies that can be used to develop biocompatible polymer coatings for iron oxide nanoparticles as MRI contrast agents for stem cell tracking.

Stem cell tracking using effective self-assembled peptide-modified superparamagnetic nanoparticles

Nanoscale ◽  
2018 ◽  
Vol 10 (34) ◽  
pp. 15967-15979 ◽  
Author(s):  
Lei Gu ◽  
Xue Li ◽  
Jing Jiang ◽  
Gang Guo ◽  
Haoxing Wu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Tracking ◽  
Superparamagnetic Iron Oxide ◽  
Mri Contrast Agents ◽  
Superparamagnetic Nanoparticles ◽  
Cell Labeling ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Peptide modified superparamagnetic iron oxide nanoparticles (SPIONs) have been developed as excellent magnetic resonance imaging (MRI) contrast agents for stem cell labeling and tracking due to their biocompatibility.

Synthesis of Iron Oxide Nanoparticles Used as MRI Contrast Agents: A Parametric Study

1999 ◽  
Vol 212 (2) ◽  
pp. 474-482 ◽  
Author(s):  
Lucia Babes ◽  
Benoı̂t Denizot ◽  
Gisèle Tanguy ◽  
Jean Jacques Le Jeune ◽  
Pierre Jallet
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Parametric Study ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Mri Contrast

scholarly journals Stem cell tracking using iron oxide nanoparticles

2014 ◽  
pp. 1641 ◽  
Author(s):  
Alexander Seifalian ◽  
Elizabeth Bull ◽  
Madani ◽  
Sheth ◽  
Mark Green ◽  
...  
Keyword(s):  
Stem Cell ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cell Tracking ◽  
Oxide Nanoparticles ◽  
Stem Cell Tracking

scholarly journals Iron oxide nanoparticles stabilized with dendritic polyglycerols as selective MRI contrast agents

Nanoscale ◽  
2014 ◽  
Vol 6 (16) ◽  
pp. 9646-9654 ◽  
Author(s):  
Daniel Nordmeyer ◽  
Patrick Stumpf ◽  
Dominic Gröger ◽  
Andreas Hofmann ◽  
Sven Enders ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Iron Oxide ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Mri Contrast Agents ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Mri Contrast

Superparamagnetic iron oxide nanoparticles with a dendritic polyglycerol (dPG) sulfate strongly bind to L- and P-selectin. Shielding of leukocytes reduces cell extravasation and binding to endothelial cells indicate inflammation specificity and thus, applicability as selective MRI contrast agent.

scholarly journals PEG-copolymer-coated iron oxide nanoparticles that avoid the reticuloendothelial system and act as kidney MRI contrast agents

Nanoscale ◽  
2018 ◽  
Vol 10 (29) ◽  
pp. 14153-14164 ◽  
Author(s):  
Vanessa Gómez-Vallejo ◽  
María Puigivila ◽  
Sandra Plaza-García ◽  
Boguslaw Szczupak ◽  
Rafael Piñol ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Reticuloendothelial System ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Mri Contrast ◽  
Gamma Counting ◽  
Magnetic Nanocarriers

PEG coated magnetic nanocarriers avoid the reticuloendothelial system, and show an MRI contrast in the kidneys. The results are supported by SPECT, gamma-counting, MRI and TEM histology.

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