Conducting polymer based electrochemical biosensors

2016 ◽  
Vol 18 (12) ◽  
pp. 8264-8277 ◽  
Author(s):  
Nihan Aydemir ◽  
Jenny Malmström ◽  
Jadranka Travas-Sejdic
Keyword(s):  
Conducting Polymer ◽  
High Sensitivity ◽  
Cost Effective ◽  
Electrochemical Biosensors ◽  
Sensitivity And Selectivity ◽  
Biological Analytes

Conducting polymer (CP)-based electrochemical biosensors have gained great attention as such biosensor platforms are easy and cost-effective to fabricate, and provide a direct electrical readout of the presence of biological analytes with high sensitivity and selectivity.

Easy-to-Fabricate K2Pd(SO3)2-Dyed Polyester Fabric with Highly Selective and Fast Response to Carbon Monoxide

2021 ◽  
Vol 21 (8) ◽  
pp. 4400-4405
Author(s):  
Junyeop Lee ◽  
Nam Gon Do ◽  
Dong Hyuk Jeong ◽  
Sae-Wan Kim ◽  
Maeum Han ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Color Change ◽  
High Sensitivity ◽  
Cost Effective ◽  
Fast Response ◽  
Polyester Fabric ◽  
High Porosity ◽  
Sensing Material ◽  
Sensitivity And Selectivity ◽  
And Performance

Carbon monoxide (CO) is an odorless, colorless, tasteless, extremely flammable, and highly toxic gas. It is produced when there is insufficient oxygen supply during the combustion of carbon to produce carbon dioxide (CO2). CO is produced from operating engines, stoves, or furnaces. CO poisoning occurs when CO accumulates in the bloodstream and can result in severe tissue damage or even death. Many types of CO sensors have been reported, including electrochemical, semiconductor metal-oxide, catalytic combustion, thermal conductivity, and infrared absorption-type for the detection of CO. However, despite their excellent selectivity and sensitivity, issues such as complexity, power consumption, and calibration limit their applications. In this study, a fabricbased colorimetric CO sensor is proposed to address these issues. Potassium disulfitopalladate (II) (K2Pd(SO3)2) is dyed on a polyester fabric as a sensing material for selective CO detection. The sensing characteristics and performance are investigated using optical instruments such as RGB sensor and spectrometer. The sensor shows immediate color change when exposed to CO at a concentration that is even lower than 20 ppm before 2 min. The fast response time of the sensor is attributed to its high porosity to react with CO. This easy-to-fabricate and cost-effective sensor can detect and prevent the leakage of CO simultaneously with high sensitivity and selectivity toward CO.

Zinc phthalocyanines with fluorinated substituents for direct sensing of carbamate and organophosphate pesticides in water

2013 ◽  
Vol 17 (10) ◽  
pp. 989-995 ◽  
Author(s):  
Dilek D. Erbahar ◽  
Mika Harbeck ◽  
Ilke Gürol ◽  
Gülay Gümüş ◽  
Emel Musluoǧlu ◽  
...  
Keyword(s):  
Chemical Sensor ◽  
High Sensitivity ◽  
Cost Effective ◽  
Negative Consequences ◽  
Aqueous Samples ◽  
Zinc Phthalocyanines ◽  
Pesticides In Water ◽  
Sensitivity And Selectivity ◽  
Quartz Crystal Microbalances ◽  
Liquid Sensing

Water pollution by pesticides as the result of intensive agriculture and horticulture has brought many negative consequences to humans and ecosystems. Among others, chemical sensor systems are under intense development for direct pesticide analysis in aqueous samples as a cost effective and simple alternative analytical method. In this work, a set of zinc phthalocyanines is studied in its liquid sensing properties using quartz crystal microbalances. Four different species selected from the two most common organophosphorus and carbamate classes of pesticides are used as test analytes. The phthalocyanines are chemically modified with different fluorinated substituents to increase sensor sensitivity and govern pesticide selectivity in order to create sensors with widely diverging analyte responses. By this means, sensors with a general high sensitivity and selectivity for the two pesticide classes were obtained and detection limits down to 0.03 mg.L-1 could be achieved. The response data of the sensors are analyzed in detail using exploratory multivariate data evaluation methods. The results show that phthalocyanine based sensors are a truly capable platform for chemical analysis systems of aqueous samples.

AMPLIFIED BIOSENSING STRATEGIES FOR THE DETECTION OF BIOLOGICALLY RELATED MOLECULES WITH SILICA NANOPARTICLES AND CONJUGATED POLYELECTROLYTES

COSMOS ◽  
2010 ◽  
Vol 06 (02) ◽  
pp. 207-219
Author(s):  
LIHUA WANG ◽  
YANYAN WANG ◽  
JIE ZOU ◽  
BIN LIU ◽  
CHUNHAI FAN
Keyword(s):  
Silica Nanoparticles ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
High Sensitivity ◽  
Cost Effective ◽  
High Specific Surface Area ◽  
Conjugated Polyelectrolytes ◽  
Signal Amplifier ◽  
Biomedical Diagnostics ◽  
Sensitivity And Selectivity

Development of rapid, field-portable and cost-effective sensors with high sensitivity and selectivity is of great importance for biomedical diagnostics, food safety and environmental monitoring. Silica nanoparticles (SiNPs) have great potential in sensor application due to their biocompatibility, controllable surface modification, excellent chemical stability and high specific surface area. On the other hand, conjugated polyelectrolytes (CPEs) have been widely used in sensor design due to their efficient Förster resonance energy transfer (FRET) to dyes and unique interaction with biomolecules. In this contribution, we briefly summarize the recent development of silica-related NP-based assays that incorporate CPEs as the signal amplifier or reporter. The silica-related NPs are used for probe immobilization, target recognition and separation, while CPEs provide amplified fluorescence signals and high sensitivity. These assays have been proven efficient for the detection of DNA, proteins, and small molecules through specific biorecognition events, such as DNA hybridization, antibody–antigen recognition and target–aptamer binding.

scholarly journals Conducting Polymer-Based Nanohybrid Transducers: A Potential Route to High Sensitivity and Selectivity Sensors

Sensors ◽  
2014 ◽  
Vol 14 (2) ◽  
pp. 3604-3630 ◽  
Author(s):  
Seon Park ◽  
Oh Kwon ◽  
Ji Lee ◽  
Jyongsik Jang ◽  
Hyeonseok Yoon
Keyword(s):  
Conducting Polymer ◽  
High Sensitivity ◽  
Sensitivity And Selectivity

scholarly journals Prospects of Organic Conducting Polymer Modified Electrodes: Enzymosensors

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Ravindra P. Singh
Keyword(s):  
Public Health ◽  
Aqueous Solution ◽  
Conducting Polymer ◽  
Modified Electrodes ◽  
High Sensitivity ◽  
Biological Molecules ◽  
Electrochemical Biosensors ◽  
Preparation Methods ◽  
Neutral Aqueous Solution ◽  
Polymer Modified Electrodes

Organic conducting polymer modified electrodes (OCPMEs) have emerged as potential candidates for electrochemical biosensors due to their easy preparation methods along with unique properties, like stability in air and being compatible with biological molecules in a neutral aqueous solution. OCPMEs are playing an important role in the improvement of public health and environment for the detection of desired analytes with high sensitivity and specificity. In this paper, we highlight the prospects of OCMEs-based electrochemical enzymosensors.

scholarly journals Recent Advances in MXene Nanocomposite-Based Biosensors

Biosensors ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 185 ◽  
Author(s):  
Jinho Yoon ◽  
Minkyu Shin ◽  
Joungpyo Lim ◽  
Ji-Young Lee ◽  
Jeong-Woo Choi
Keyword(s):  
Inorganic Compounds ◽  
High Sensitivity ◽  
High Conductivity ◽  
Optical Biosensors ◽  
Electrochemical Biosensors ◽  
Synthesis Methods ◽  
Two Dimensional ◽  
Recent Advances ◽  
Sensitivity And Selectivity

The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop biosensors for achieving high sensitivity and selectivity. Among the latest nanomaterials attracting attention, MXene is one of the best materials for the development of biosensors because of its various superior properties. MXenes are two-dimensional inorganic compounds with few atomic layers that possess excellent characteristics including high conductivity and superior fluorescent, optical, and plasmonic properties. In this review, advanced biosensors developed on the basis of the MXene nanocomposite are discussed with the selective overview of recently reported studies. For this, introduction of the MXene including the definition, synthesis methods, and its properties are discussed. Next, MXene-based electrochemical biosensors and MXene-based fluorescent/optical biosensors are provided, which are developed on the basis of the exceptional properties of the MXene nanocomposite. This review will suggest the direction for use of the Mxene nanocomposite to develop advanced biosensors with high sensitivity and selectivity.

scholarly journals Electrochemical Biosensors Based on Nanomaterials for Early Detection of Alzheimer’s Disease

Sensors ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 4748 ◽  
Author(s):  
Celia Toyos-Rodríguez ◽  
Francisco Javier García-Alonso ◽  
Alfredo de la Escosura-Muñiz
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Early Detection ◽  
High Sensitivity ◽  
Cost Effective ◽  
Diagnostic Techniques ◽  
Electrochemical Biosensing ◽  
Biological Recognition ◽  
Sensitivity And Selectivity ◽  
Cost Effective Alternative

Alzheimer’s disease (AD) is an untreatable neurodegenerative disease that initially manifests as difficulty to remember recent events and gradually progresses to cognitive impairment. The incidence of AD is growing yearly as life expectancy increases, thus early detection is essential to ensure a better quality of life for diagnosed patients. To reach that purpose, electrochemical biosensing has emerged as a cost-effective alternative to traditional diagnostic techniques, due to its high sensitivity and selectivity. Of special relevance is the incorporation of nanomaterials in biosensors, as they contribute to enhance electron transfer while promoting the immobilization of biological recognition elements. Moreover, nanomaterials have also been employed as labels, due to their unique electroactive and electrocatalytic properties. The aim of this review is to add value in the advances achieved in the detection of AD biomarkers, the strategies followed for the incorporation of nanomaterials and its effect in biosensors performance.

scholarly journals Recent Development of Morphology Controlled Conducting Polymer Nanomaterial-Based Biosensor

2020 ◽  
Vol 10 (17) ◽  
pp. 5889
Author(s):  
Sunghun Cho ◽  
Jun Seop Lee
Keyword(s):  
Conducting Polymer ◽  
High Surface ◽  
Volume Ratio ◽  
High Sensitivity ◽  
Cycle Stability ◽  
Working Temperature ◽  
Transfer Processes ◽  
Widespread Implementation ◽  
Low Concentrations ◽  
Biological Analytes

Biosensors are of particular importance for the detection of biological analytes at low concentrations. Conducting polymer nanomaterials, which often serve as sensing transducers, are renowned for their small dimensions, high surface-to-volume ratio, and amplified sensitivity. Despite these traits, the widespread implementation of conventional conducting polymer nanomaterials is hampered by their scarcity and lack of structural uniformity. Herein, a brief overview of the latest developments in the synthesis of morphologically tunable conducting polymer-based biosensors is discussed. Research related to the dimensional (0, 1, 2, and 3D) hetero-nanostructures of conducting polymers are highlighted in this paper, and how these structures affect traits such as the speed of charge transfer processes, low-working temperature, high sensitivity and cycle stability are discussed.

One-pot synthesis of dendritic Pt3Ni nanoalloys as nonenzymatic electrochemical biosensors with high sensitivity and selectivity for dopamine detection

Nanoscale ◽  
2017 ◽  
Vol 9 (31) ◽  
pp. 10998-11003 ◽  
Author(s):  
Ge Gao ◽  
Zongkui Zhang ◽  
Kai Wang ◽  
Qiang Yuan ◽  
Xun Wang
Keyword(s):  
High Sensitivity ◽  
Electrochemical Biosensors ◽  
Facile Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
Dopamine Detection ◽  
Sensitivity And Selectivity

We report a facile synthesis of dendritic Pt3Ni nanoalloys and their applications for dopamine biosensors. The LOD of dopamine on dendritic Pt3Ni nanoalloy microelectrodes can decrease down to 0.01 μM.

scholarly journals Colorimetric detection of individual biothiols by tailor made reactions with silver nanoprisms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pei Li ◽  
Sang Mo Lee ◽  
Hyo Yong Kim ◽  
Soohyun Kim ◽  
Steve Park ◽  
...  
Keyword(s):  
Human Serum ◽  
Colorimetric Detection ◽  
Chloride Ion ◽  
High Sensitivity ◽  
Cost Effective ◽  
Colorimetric Sensing ◽  
Practical Applications ◽  
Silver Nanoprisms ◽  
Sensing Platform ◽  
Sensitivity And Selectivity

AbstractWe herein described a rapid, sensitive, and selective colorimetric sensing platform for biothiols in human serum, which relies on the dual functions of biothiols as anti-etching and aggregating agent for silver nanoprisms (AgNPRs). In principle, the target biothiols that bind to the surface of AgNPRs through Ag–S covalent interactions protect the AgNPRs from being etched by chloride ion (Cl−) in human serum, thus exhibiting the blue/purple color that is indicative of AgNPRs. On the other hand, the color of AgNPRs turned to yellow in the absence of biothiols or the presence of non-sulfur-containing amino acids, indicating the formation of small silver nanoparticles (AgNPs). Importantly, we found that individual biothiols (Hcy, Cys, and GSH) exert not only the anti-etching effect, but also the aggregating effect on AgNPRs, which can be modulated by simply tuning the pH conditions, and this consequently allows for the discriminative detection of each biothiol. Based on this simple and cost-effective strategy, we successfully determined the Hcy, Cys, and GSH in human serum with high sensitivity and selectivity within 10 min, demonstrating the diagnostic capability and potential in practical applications.

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