A theoretical study of potentially observable chirality-sensitive NMR effects in molecules

2015 ◽  
Vol 17 (35) ◽  
pp. 22642-22651 ◽  
Author(s):  
Piotr Garbacz ◽  
Janusz Cukras ◽  
Michał Jaszuński
Keyword(s):  
Theoretical Study ◽  
Direct Determination ◽  
Nmr Analysis ◽  
Fluorine Nucleus ◽  
Shielding Tensor ◽  
Derivatives Of

Derivatives of fluorocyclopropene have large antisymmetric parts of the fluorine nucleus shielding tensor, thus they are promising molecules for direct determination of chirality by NMR analysis.

THE SIGNIFICANCE OF HUMAN BLOOD TRYPSIN; DIRECT DETERMINATION OF THROMBIN AND PLASMIN IN HUMAN PLASMA

1962 ◽  
Vol 40 (12) ◽  
pp. 1725-1735 ◽  
Author(s):  
Edward Ronwin
Keyword(s):  
Human Plasma ◽  
Human Blood ◽  
Direct Determination ◽  
Precursor Protein ◽  
Common Precursor ◽  
Conversion System ◽  
Human Thrombin ◽  
Derivatives Of

The previously described method for human plasmin determination has been simplified and applied directly to plasma. A virtually identical method for the direct determination of human thrombin in plasma is also presented. Both procedures are quantitative and clinically feasible. The existence in plasma of a non-clotting, only slightly fibrinolytic, active tryptic enzyme, Human Blood Trypsin, is firmly established by the data. The suggestion is made that human blood trypsin may be the activator in the proenzyme to enzyme conversion system for both plasmin and thrombin. Further, both enzymes may arise from different derivatives of a common precursor protein.

THE SIGNIFICANCE OF HUMAN BLOOD TRYPSIN; DIRECT DETERMINATION OF THROMBIN AND PLASMIN IN HUMAN PLASMA

1962 ◽  
Vol 40 (1) ◽  
pp. 1725-1735
Author(s):  
Edward Ronwin
Keyword(s):  
Human Plasma ◽  
Human Blood ◽  
Direct Determination ◽  
Precursor Protein ◽  
Common Precursor ◽  
Conversion System ◽  
Human Thrombin ◽  
Derivatives Of

The previously described method for human plasmin determination has been simplified and applied directly to plasma. A virtually identical method for the direct determination of human thrombin in plasma is also presented. Both procedures are quantitative and clinically feasible. The existence in plasma of a non-clotting, only slightly fibrinolytic, active tryptic enzyme, Human Blood Trypsin, is firmly established by the data. The suggestion is made that human blood trypsin may be the activator in the proenzyme to enzyme conversion system for both plasmin and thrombin. Further, both enzymes may arise from different derivatives of a common precursor protein.

scholarly journals The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide

Microbiology ◽  
2006 ◽  
Vol 152 (4) ◽  
pp. 989-1000 ◽  
Author(s):  
Michael J. Allen ◽  
Graham F. White ◽  
Andrew P. Morby
Keyword(s):  
Escherichia Coli ◽  
Nucleic Acids ◽  
Transcriptional Profiling ◽  
Direct Determination ◽  
Open Reading Frames ◽  
E Coli ◽  
Polyhexamethylene Biguanide ◽  
Wide Range ◽  
Derivatives Of

The global response of Escherichia coli to the broad-spectrum biocide polyhexamethylene biguanide (PHMB) was investigated using transcriptional profiling. The transcriptional analyses were validated by direct determination of the PHMB-tolerance phenotypes of derivatives of E. coli MG1655 carrying either insertionally inactivated genes and/or plasmids expressing the cognate open reading frames from a heterologous promoter in the corresponding chromosomally inactivated strains. The results showed that a wide range of genes was altered in transcriptional activity and that all of the corresponding knockout strains subsequently challenged with biocide were altered in tolerance. Of particular interest was the induction of the rhs genes and the implication of enzymes involved in the repair/binding of nucleic acids in the generation of tolerance, suggesting a novel dimension in the mechanism of action of PHMB based on its interaction with nucleic acids.

The Direct Determination of I131 in Heterogeneous Fecal Specimens

1961 ◽  
Vol 41 (4) ◽  
pp. 380-384 ◽  
Author(s):  
Arthur F. Dratz ◽  
James C. Coberly
Keyword(s):  
Direct Determination

A New Method for Direct Determination of the Recoilless Fraction with Application to Magnetic Nanoparticles

2002 ◽  
Vol 721 ◽  
Author(s):  
Monica Sorescu
Keyword(s):  
Room Temperature ◽  
Average Particle Size ◽  
Direct Determination ◽  
Average Particle ◽  
Lattice Method ◽  
Recoilless Fraction ◽  
Single Room ◽  
Magnetite Particles ◽  
Physical Mixtures

AbstractWe propose a two-lattice method for direct determination of the recoilless fraction using a single room-temperature transmission Mössbauer measurement. The method is first demonstrated for the case of iron and metallic glass two-foil system and is next generalized for the case of physical mixtures of two powders. We further apply this method to determine the recoilless fraction of hematite and magnetite particles. Finally, we provide direct measurement of the recoilless fraction in nanohematite and nanomagnetite with an average particle size of 19 nm.

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