Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection

2015 ◽  
Vol 17 (15) ◽  
pp. 9951-9958 ◽  
Author(s):  
Yuri Kamon ◽  
Yukiya Kitayama ◽  
Akiko N. Itakura ◽  
Kyoko Fukazawa ◽  
Kazuhiko Ishihara ◽  
...  

We studied the effects of layer thickness and grafting density of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) thin layers as specific ligands for the highly sensitive binding of C-reactive protein (CRP).

2014 ◽  
Vol 456 ◽  
pp. 32-37 ◽  
Author(s):  
Sandeep Kumar Vashist ◽  
Gregor Czilwik ◽  
Thomas van Oordt ◽  
Felix von Stetten ◽  
Roland Zengerle ◽  
...  

2017 ◽  
Vol 9 (6) ◽  
pp. 994-1003 ◽  
Author(s):  
Robert Nooney ◽  
Valerie Rebello ◽  
Gemma Keegan ◽  
Claire L. O'Connell ◽  
Daragh Byrne ◽  
...  

A novel dissolution approach was used to achieve enhanced sensitivity in a nanoparticle (NP) immunoassay for the detection of a cardiovascular disease marker, C-reactive protein (CRP).


2006 ◽  
Vol 153 (3) ◽  
pp. 54 ◽  
Author(s):  
K.-K. Sin ◽  
C.P.-Y. Chan ◽  
W.-M. Leung ◽  
M. Seydack ◽  
R. Renneberg

2016 ◽  
Vol 52 (20) ◽  
pp. 3883-3886 ◽  
Author(s):  
Ryo Matsuura ◽  
Keiko Tawa ◽  
Yukiya Kitayama ◽  
Toshifumi Takeuchi

A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence.


RSC Advances ◽  
2014 ◽  
Vol 4 (55) ◽  
pp. 29022-29031 ◽  
Author(s):  
Yi Zhang ◽  
Denise E. Charles ◽  
Deirdre M. Ledwith ◽  
Damian Aherne ◽  
Stephen Cunningham ◽  
...  

Rapid, wash-free highly sensitive detection of C-reactive protein is reported using nanoplate biosensor sols.


2014 ◽  
Author(s):  
Sandeep Kumar Vashist ◽  
Sandeep Kumar Vashist ◽  
Gregor Czilwik ◽  
Thomas van Oordt ◽  
Felix von Stetten ◽  
...  

2017 ◽  
Vol 5 (45) ◽  
pp. 23794-23804 ◽  
Author(s):  
Donghua Xie ◽  
Yue Ma ◽  
Yue Gu ◽  
Hongjian Zhou ◽  
Haimin Zhang ◽  
...  

Bifunctional NH2-MIL-88(Fe) nanooctahedra have been successfully fabricated for highly sensitive and specific recognition as well as efficient removal of arsenate.


2021 ◽  
Author(s):  
Nguyen Thanh Thao ◽  
Thi Xoan Hoang ◽  
Thang Bach Phan ◽  
Jae Young Kim ◽  
Hanh Kieu Thi Ta ◽  
...  

Potential applications of metal enhanced fluorescence (MEF) devices are associated with biosensors for the detection of trace amounts of biosciences, biotechnology, and pathogens that are relevant to medical diagnostics and...


2017 ◽  
Vol 5 (21) ◽  
pp. 3919-3926 ◽  
Author(s):  
Yan Xing ◽  
Qin Gao ◽  
Yanmin Zhang ◽  
Le Ma ◽  
Kang Yong Loh ◽  
...  

Monodispersed PAA-Au/Fe3O4 NPs were engineered for highly sensitive CRP assay with zwitterionic glycerophosphoryl choline as the co-blocking agent.


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