Unusual denaturation trajectory of bovine gamma globulin studied by fluorescence correlation spectroscopy

2015 ◽  
Vol 17 (29) ◽  
pp. 19139-19148 ◽  
Author(s):  
Moupriya Nag ◽  
Debajyoti Das ◽  
Diptankar Bandyopadhyay ◽  
Soumen Basak

FCS study of GdnHCl-induced denaturation of the multi-domain protein, gamma globulin, showed unexpected features such as initial compactification followed by electrostatic interaction-driven expansion before disintegration into small fragments.

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lutz Langguth ◽  
Agata Szuba ◽  
Sander A. Mann ◽  
Erik C. Garnett ◽  
Gijsje H. Koenderink ◽  
...  

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