Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T2 contrast enhancement in magnetic resonance imaging

2015 ◽  
Vol 51 (56) ◽  
pp. 11194-11197 ◽  
Author(s):  
Alexandre D. A. Zottis ◽  
Jeovandro M. Beltrame ◽  
Luciano R. S. Lara ◽  
Thiago G. Costa ◽  
Mateus J. Feldhaus ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Water Soluble ◽  
Resonance Imaging ◽  
Promising Candidate ◽  
Magnetite Nanoparticle ◽  
Iron Oxide Magnetic Nanoparticles ◽  
Environmentally Friendly Approach

We describe herein a novel type of monodisperse water-soluble magnetite nanoparticle coated with pheomelanin using an environmentally-friendly approach in aqueous medium.

scholarly journals Immobilization of Iron Oxide Magnetic Nanoparticles for Enhancement of Vessel Wall Magnetic Resonance Imaging—AnEx VivoFeasibility Study

2010 ◽  
Vol 21 (8) ◽  
pp. 1408-1412 ◽  
Author(s):  
Binh Thai Nguyen ◽  
Praveen Kumar Vemula ◽  
Dimitrios Mitsouras ◽  
Peng Yu ◽  
Ming Tao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Vessel Wall ◽  
Resonance Imaging ◽  
Iron Oxide Magnetic Nanoparticles

Magnetic Resonance Imaging of Tumors with the Use of Iron Oxide Magnetic Nanoparticles as a Contrast Agent

2017 ◽  
Vol 162 (6) ◽  
pp. 808-811 ◽  
Author(s):  
A. S. Semkina ◽  
M. A. Abakumov ◽  
N. F. Grinenko ◽  
A. A. Lipengolts ◽  
N. V. Nukolova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Resonance Imaging ◽  
Iron Oxide Magnetic Nanoparticles

Magnetic iron oxide nanoparticles asT1contrast agents for magnetic resonance imaging

2018 ◽  
Vol 6 (6) ◽  
pp. 1280-1290 ◽  
Author(s):  
Y. Bao ◽  
J. A. Sherwood ◽  
Z. Sun
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Synthesis Parameters

This review discusses several aspects regarding ultrasmall magnetic nanoparticles asT1contrast agents, including synthesis, parameters affectingT1, and applications.

One-pot synthesis of water-soluble and biocompatible superparamagnetic gadolinium-doped iron oxide nanoclusters

2020 ◽  
Vol 8 (7) ◽  
pp. 1432-1444 ◽  
Author(s):  
Huijing Xiang ◽  
Pingli Dong ◽  
Lei Pi ◽  
Zhijie Wang ◽  
Tingting Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Water Soluble ◽  
Resonance Imaging ◽  
One Pot ◽  
One Pot Synthesis ◽  
Magnetic Resonance Imaging Mri

The synthesis of superparamagnetic nanoclusters is critical for ultra-sensitive magnetic resonance imaging (MRI).

scholarly journals Intracellular labeling and quantification process by magnetic resonance imaging using iron oxide magnetic nanoparticles in rat C6 glioma cell line

2012 ◽  
Vol 10 (2) ◽  
pp. 216-221 ◽  
Author(s):  
Javier Bustamante Mamani ◽  
Lorena Favaro Pavon ◽  
Liza Aya Mabuchi Miyaki ◽  
Tatiana Tais Sibov ◽  
Fabiana Rossan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Glioma Cells ◽  
C6 Glioma ◽  
C6 Glioma Cells ◽  
Resonance Imaging ◽  
Iron Oxide Magnetic Nanoparticles ◽  
Transfection Agent ◽  
Rat C6 Glioma

OBJECTIVE: To assess intracellular labeling and quantification by magnetic resonance imaging using iron oxide magnetic nanoparticles coated with biocompatible materials in rat C6 glioma cells in vitro. These methods will provide direction for future trials of tumor induction in vivo as well as possible magnetic hyperthermia applications. METHODS: Aminosilane, dextran, polyvinyl alcohol, and starch-coated magnetic nanoparticles were used in the qualitative assessment of C6 cell labeling via light microscopy. The influence of the transfection agent poly-L-lysine on cellular uptake was examined. The quantification process was performed by relaxometry analysis in T1 and T2weighted phantom images. RESULTS: Light microscopy revealed that the aminosilane-coated magnetic nanoparticles alone or complexed with poly-L-lysine showed higher cellular uptake than did the uncoated magnetic particles. The relaxivities of the aminosilane-coated magnetic nanoparticles with a hydrodynamic diameter of 50nm to a 3-T field were r1=(6.1±0.3)×10-5 ms-1mL/µg, r2=(5.3±0.1)× 10-4 ms-1mL/µg, with a ratio of r2 / r1 ≅ 9. The iron uptake in the cells was calculated by analyzing the relaxation rates (R1 and R2) using a mathematical relationship. CONCLUSIONS: C6 glioma cells have a high uptake efficiency for aminosilane-coated magnetic nanoparticles complexed with the transfection agent poly-L-lysine. The large ratio r2 / r1 ≅ 9 indicates that these magnetic nanoparticles are ideal for quantification by magnetic resonance imaging with T2-weighted imaging techniques.

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