Mesoporous silica-coated quantum dots functionalized with folic acid for lung cancer cell imaging

2015 ◽  
Vol 7 (22) ◽  
pp. 9649-9654 ◽  
Author(s):  
Shang Zhou ◽  
Danqun Huo ◽  
Changjun Hou ◽  
Mei Yang ◽  
Huanbao Fa ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Folic Acid ◽  
Mesoporous Silica ◽  
Tumor Cells ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Lung Cancer Cell ◽  
Normal Cells ◽  
Functionalized Mesoporous Silica

A folate-functionalized mesoporous silica-coated CdTe QD fluorescent probe is developed to distinguish tumor cells from normal cells. It exhibited superior selectivity and lower cytotoxicity than the unfunctionalized probe.

Functionalization of upconverted luminescent NaYF4 : Yb/Er nanocrystals by folic acid–chitosan conjugates for targeted lung cancer cell imaging

2011 ◽  
Vol 21 (21) ◽  
pp. 7661 ◽  
Author(s):  
Qingtao Chen ◽  
Xin Wang ◽  
Fenghua Chen ◽  
Qingbin Zhang ◽  
Bing Dong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Folic Acid ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Lung Cancer Cell ◽  
Cancer Cell Imaging

pH-sensitive tangeretin-ZnO quantum dots exert apoptotic and anti-metastatic effects in metastatic lung cancer cell line

2018 ◽  
Vol 92 ◽  
pp. 477-488 ◽  
Author(s):  
A. Roshini ◽  
Srikanth Jagadeesan ◽  
Lakshmi Arivazhagan ◽  
Young-Jae Cho ◽  
Jong-Hwan Lim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Ph Sensitive ◽  
Lung Cancer Cell Line ◽  
Metastatic Lung Cancer ◽  
Lung Cancer Cell ◽  
Metastatic Lung

Folic Acid-Conjugated Mesoporous Silica Nanoparticles and MicroRNA-128-3p Combined with Adriamycin Alleviates the Progression of Non-Small Cell Lung Cancer

2021 ◽  
Vol 11 (9) ◽  
pp. 1714-1721
Author(s):  
Zhijun Zhu ◽  
Da Ni ◽  
Jiping Teng ◽  
Youshuang Cheng ◽  
Bufeng Zhuang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Folic Acid ◽  
Side Effects ◽  
Mesoporous Silica ◽  
Mesoporous Silica Nanoparticles ◽  
Small Cell ◽  
Small Cell Lung ◽  
Low Toxicity

Non-small cell lung cancer (NSCLC) is still a threat to people worldwide. In the current study, we aimed to investigate the effect of folic acid (FA) and Adriamycin on NSCLC. Our work modified Adriamycin with microRNA (miR)-128-3p-loaded FA-mesoporous silica nanoparticles (MSN) (Adriamycin/miR/MSN-FA) or with Adriamycin/miR/MSN. The synthesized nanoparticles’ in vitro drug release and hydrodynamic characteristics were detected. Then Adriamycin and nanoparticles were applied to treat NSCLC cells followed by analysis of cell proliferation by MTT, cytometry and clone formation assay, apoptosis-related proteins by Western blot, and in vitro absorption by Rhodamine B staining. Animal model was set up to detect in vivo impact of nanoparticles. Adriamycin/miR/MSN-FA nanoparticles released Adriamycin in a controlled manner, inhibited colony formation and cell proliferation. Besides, nanoparticles promoted cell apoptosis and upregulated cleaved Caspase-3 and PARP. Moreover, Adriamycin/miR/MSN-FA significantly aggregated in tumor with high concentration of Adriamycin, thereby inhibiting NSCLC tumor progression with low toxicity and side effects. Adriamycin/miR/MSN-FA nanoparticles could effectively inhibit the progression of NSCLC with low toxicity and side effects.

Immobilization of gold nanoparticles on folate-conjugated dendritic mesoporous silica-coated reduced graphene oxide nanosheets: a new nanoplatform for curcumin pH-controlled and targeted delivery

Soft Matter ◽  
2018 ◽  
Vol 14 (12) ◽  
pp. 2400-2410 ◽  
Author(s):  
Samira Malekmohammadi ◽  
Hassan Hadadzadeh ◽  
Hossein Farrokhpour ◽  
Zahra Amirghofran
Keyword(s):  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Folic Acid ◽  
Mesoporous Silica ◽  
Reduced Graphene Oxide ◽  
Targeted Delivery ◽  
Cell Imaging ◽  
Graphene Oxide Nanosheets ◽  
Reduced Graphene ◽  
Gold Nps

A nanocarrier for curcumin targeted delivery and cell imaging was prepared by immobilization of gold NPs on the folic acid-modified dendritic mesoporous silica-coated reduced graphene oxide nanosheets.

A rapid response “Turn-On” fluorescent probe for nitroreductase detection and its application in hypoxic tumor cell imaging

The Analyst ◽  
2015 ◽  
Vol 140 (2) ◽  
pp. 574-581 ◽  
Author(s):  
Jian Xu ◽  
Shaobo Sun ◽  
Qian Li ◽  
Ying Yue ◽  
Yingdong Li ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Rapid Response ◽  
Indirect Detection ◽  
Turn On ◽  
Hypoxic Tumor

A novel “Turn-On” fluorescent probe, quaternarized 4-pyridinyl-substituted BODIPY dye by incorporating a 5-nitrofuran moiety, was developed and applied for imaging the hypoxic status of tumor cells by the indirect detection of nitroreductase.

scholarly journals Folic acid targeted Mn:ZnS quantum dots for theranostic applications of cancer cell imaging and therapy

2016 ◽  
pp. 413 ◽  
Author(s):  
Faruq Mohammad ◽  
Ibrahim birma Bwatanglang ◽  
Nor Azah Yusof ◽  
Jaafar Abdullah ◽  
Mohd Zobir Hussein ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Folic Acid ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Cancer Cell Imaging ◽  
Theranostic Applications

AIEgen-Functionalized Mesoporous Silica Gated by Cyclodextrin-Modified CuS for Cell Imaging and Chemo-Photothermal Cancer Therapy

2017 ◽  
Vol 10 (15) ◽  
pp. 12155-12163 ◽  
Author(s):  
Qing-Lan Li ◽  
Duo Wang ◽  
Yuanzheng Cui ◽  
Zhiying Fan ◽  
Li Ren ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Cell Imaging ◽  
Functionalized Mesoporous Silica
Sign in / Sign up

Export Citation Format

Share Document