Direct and quantitative detection of dicyandiamide (DCD) in milk using surface-enhanced Raman spectroscopy

2015 ◽  
Vol 7 (9) ◽  
pp. 3869-3875 ◽  
Author(s):  
Xiang Lin ◽  
Wu-Li-Ji Hasi ◽  
Xiu-Tao Lou ◽  
Si-qin-gao-wa Han ◽  
Dian-Yang Lin ◽  
...  

A SERS method has been developed to directly and quantitatively detect dicyandiamide in milk without any sample pretreatment through an internal standard method.

2005 ◽  
Vol 77 (11) ◽  
pp. 3563-3569 ◽  
Author(s):  
Dongmao Zhang ◽  
Yong Xie ◽  
Shirshendu K. Deb ◽  
V. Jo Davison ◽  
Dor Ben-Amotz

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.


2020 ◽  
Vol 8 (21) ◽  
pp. 7051-7058
Author(s):  
Weng-I Katherine Chio ◽  
Suresh Moorthy ◽  
Jayakumar Perumal ◽  
Dinish U. S. ◽  
Ivan P. Parkin ◽  
...  

A novel nanosensing platform was developed for the quantitative detection of creatinine of clinically relevant concentrations via UV-Vis spectroscopy and surface-enhanced Raman spectroscopy.


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